Mitogen-activated protein kinase-mediated phosphorylation of peroxiredoxin 6 regulates its phospholipase A(2) activity. - Wikidata - awgldk - TriplyDB

Mitogen-activated protein kinase-mediated phosphorylation of peroxiredoxin 6 regulates its phospholipase A(2) activity.

Mitogen-activated protein kinase-mediated phosphorylation of peroxiredoxin 6 regulates its phospholipase A(2) activity.

http://www.wikidata.org/entity/Q37406188

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Intracellular targeting of peroxiredoxin 6 to lysosomal organelles requires MAPK activity and binding to 14-3-3ε Stop the flow: a paradigm for cell signaling mediated by reactive oxygen species in the pulmonary endothelium The serpentine path to a novel mechanism-based inhibitor of acute inflammatory lung injury p67(phox) terminates the phospholipase A(2)-derived signal for activation of NADPH oxidase (NOX2)Peroxiredoxin VI oxidation in cerebrospinal fluid correlates with traumatic brain injury outcome Comparison of glutathione peroxidase 1 and peroxiredoxin 6 in protection against oxidative stress in the mouse lung.Proteomic profiling of differentially expressed proteins from Bax inhibitor-1 knockout and wild type mice.Peroxiredoxin 6 phosphorylation and subsequent phospholipase A2 activity are required for agonist-mediated activation of NADPH oxidase in mouse pulmonary microvascular endothelium and alveolar macrophages.Peroxiredoxins in plants and cyanobacteria.Deficiency of Prdx6 in lens epithelial cells induces ER stress response-mediated impaired homeostasis and apoptosis.Energy determinants GAPDH and NDPK act as genetic modifiers for hepatocyte inclusion formation.Solution structure of the reduced form of human peroxiredoxin-6 elucidated using zero-length chemical cross-linking and homology modelling.Protein glutathionylation in the regulation of peroxiredoxins: a family of thiol-specific peroxidases that function as antioxidants, molecular chaperones, and signal modulators.Membrane depolarization is the trigger for PI3K/Akt activation and leads to the generation of ROS.Probing structures of large protein complexes using zero-length cross-linking.Increased phospholipase A2 activity with phosphorylation of peroxiredoxin 6 requires a conformational change in the protein.Allelic variants of glutathione S-transferase P1-1 differentially mediate the peroxidase function of peroxiredoxin VI and alter membrane lipid peroxidation.A novel lysophosphatidylcholine acyl transferase activity is expressed by peroxiredoxin 6 A novel nontoxic inhibitor of the activation of NADPH oxidase reduces reactive oxygen species production in mouse lung.Peroxiredoxin 6 homodimerization and heterodimerization with glutathione S-transferase pi are required for its peroxidase but not phospholipase A2 activity.Proteomic analysis of the supernatant of red blood cell units: the effects of storage and leucoreduction The Antioxidant Peroxiredoxin 6 (Prdx6) Exhibits Different Profiles in the Livers of Seawater- and Fresh Water-Acclimated Milkfish, Chanos chanos, upon Hypothermal Challenge.The accumulation of lipids and proteins during red blood cell storage: the roles of leucoreduction and experimental filtration.Sumoylation-deficient Prdx6 gains protective function by amplifying enzymatic activity and stability and escapes oxidative stress-induced aberrant Sumoylation.Peroxiredoxin 6: a bifunctional enzyme with glutathione peroxidase and phospholipase A₂ activities.Novel roles of peroxiredoxins in inflammation, cancer and innate immunity.Binding sites for interaction of peroxiredoxin 6 with surfactant protein A.Critical role of peroxiredoxin 6 in the repair of peroxidized cell membranes following oxidative stress Peroxiredoxin 6 in the repair of peroxidized cell membranes and cell signaling.Phox activity of differentiated PLB-985 cells is enhanced, in an agonist specific manner, by the PLA2 activity of Prdx6-PLA2.Binding of peroxiredoxin 6 to substrate determines differential phospholipid hydroperoxide peroxidase and phospholipase A(2) activities.Erk1/2-dependent phosphorylation of PKCalpha at threonine 638 in hippocampal 5-HT(1A) receptor-mediated signaling.The phospholipase A2 activity of peroxiredoxin 6 modulates NADPH oxidase 2 activation via lysophosphatidic acid receptor signaling in the pulmonary endothelium and alveolar macrophages.Peroxiredoxin 6 mediates Gαi protein-coupled receptor inactivation by cJun kinase.The role of peroxiredoxin 6 in neutralization of X-ray mediated oxidative stress: effects on gene expression, preservation of radiosensitive tissues and postradiation survival of animals.

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Mitogen-activated protein kinase-mediated phosphorylation of peroxiredoxin 6 regulates its phospholipase A(2) activity.

http://www.wikidata.org/entity/Q37406188

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on May 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Mitogen-activated protein kina ...... regulates its phospholipase A

@nl

Mitogen-activated protein kina ...... s phospholipase A(2) activity.

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type

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Mitogen-activated protein kina ...... regulates its phospholipase A

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Mitogen-activated protein kina ...... s phospholipase A(2) activity.

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Mitogen-activated protein kina ...... regulates its phospholipase A

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Mitogen-activated protein kina ...... s phospholipase A(2) activity.

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Biochemical Journal

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Mitogen-activated protein kina ...... s phospholipase A(2) activity.

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P2093

Altaf Kazi

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Aron B Fisher

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Chandra Dodia

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David W Speicher

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Ibrul Chowdhury

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Jhang Ho Pak

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Sheldon I Feinstein

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Yefim Manevich

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Yongzheng Wu

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P2860

1-Cys peroxiredoxin, a bifunctional enzyme with glutathione peroxidase and phospholipase A2 activities

Regulation of peroxiredoxin I activity by Cdc2-mediated phosphorylation

cPLA2 is phosphorylated and activated by MAP kinase

1-Cys peroxiredoxin overexpression protects cells against phospholipid peroxidation-mediated membrane damage

Serine 727 phosphorylation and activation of cytosolic phospholipase A2 by MNK1-related protein kinases

Structure, mechanism and regulation of peroxiredoxins

AOP2 (antioxidant protein 2): structure and function of a unique thiol-specific antioxidant

Intracellular messenger function of hydrogen peroxide and its regulation by peroxiredoxins

Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles

Identification of a human cDNA clone for lysosomal type Ca2+-independent phospholipase A2 and properties of the expressed protein

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669-679

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scholarly article

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10.1042/BJ20082061

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3

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419

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2009-05-01T00:00:00Z

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23784328

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19140803

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phosphorylation

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2770719

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