AAV2/8 vectors purified from culture medium with a simple and rapid protocol transduce murine liver, muscle, and retina efficiently.

AAV2/8 vectors purified from culture medium with a simple and rapid protocol transduce murine liver, muscle, and retina efficiently.

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http://www.wikidata.org/entity/Q37406911
Scalable downstream strategies for purification of recombinant adeno- associated virus vectors in light of the properties.Naturally enveloped AAV vectors for shielding neutralizing antibodies and robust gene delivery in vivo.Improved dual AAV vectors with reduced expression of truncated proteins are safe and effective in the retina of a mouse model of Stargardt disease.Rhodopsin targeted transcriptional silencing by DNA-binding.A Comprehensive Map of CNS Transduction by Eight Recombinant Adeno-associated Virus Serotypes Upon Cerebrospinal Fluid Administration in Pigs.Effective delivery of large genes to the retina by dual AAV vectors.Copackaging of multiple adeno-associated viral vectors in a single production step.Manufacturing of recombinant adeno-associated viruses using mammalian expression platforms.Targeted delivery of AAV-transduced mesenchymal stromal cells to hepatic tissue for ex vivo gene therapy.Simple downstream process based on detergent treatment improves yield and in vivo transduction efficacy of adeno-associated virus vectors.Retinal transduction profiles by high-capacity viral vectors.Efficient gene delivery to the cone-enriched pig retina by dual AAV vectors.AAV-mediated transcription factor EB (TFEB) gene delivery ameliorates muscle pathology and function in the murine model of Pompe Disease.Dual AAV Vectors for Stargardt Disease.Triple Vectors Expand AAV Transfer Capacity in the Retina.Ultrafiltered recombinant AAV8 vector can be safely administered in vivo and efficiently transduces liver.High-throughput screening identifies kinase inhibitors that increase dual AAV vectors transduction <i>in vitro</i> and in mouse retina.
P2860

AAV2/8 vectors purified from culture medium with a simple and rapid protocol transduce murine liver, muscle, and retina efficiently.

Item
http://www.wikidata.org/entity/Q37406911
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 11 October 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
AAV2/8 vectors purified from c ...... uscle, and retina efficiently.
@en
AAV2/8 vectors purified from c ...... uscle, and retina efficiently.
@nl
type
label
AAV2/8 vectors purified from c ...... uscle, and retina efficiently.
@en
AAV2/8 vectors purified from c ...... uscle, and retina efficiently.
@nl
prefLabel
AAV2/8 vectors purified from c ...... uscle, and retina efficiently.
@en
AAV2/8 vectors purified from c ...... uscle, and retina efficiently.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
AAV2/8 vectors purified from c ...... uscle, and retina efficiently.
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P932