Double bromodomain-containing gene Brd2 is essential for embryonic development in mouse - Wikidata - awgldk - TriplyDB

Double bromodomain-containing gene Brd2 is essential for embryonic development in mouse

Double bromodomain-containing gene Brd2 is essential for embryonic development in mouse

http://www.wikidata.org/entity/Q37407183

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The role of human bromodomains in chromatin biology and gene transcription Epigenetic regulators as promising therapeutic targets in acute myeloid leukemia The Bromodomain and Extra-Terminal Domain (BET) Family: Functional Anatomy of BET Paralogous Proteins Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes Functions of BET proteins in erythroid gene expression BET domain co-regulators in obesity, inflammation and cancer A combination of H2A.Z and H4 acetylation recruits Brd2 to chromatin during transcriptional activation Control of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genes The C-terminal domain of Brd2 is important for chromatin interaction and regulation of transcription and alternative splicing.Characterization of BRD4 during mammalian postmeiotic sperm development.Bromodomain and extraterminal proteins suppress NF-E2-related factor 2-mediated antioxidant gene expression.Brd2 disruption in mice causes severe obesity without Type 2 diabetes.Pleiotrophin antagonizes Brd2 during neuronal differentiation.Writers and readers of histone acetylation: structure, mechanism, and inhibition GABAergic neuron deficit as an idiopathic generalized epilepsy mechanism: the role of BRD2 haploinsufficiency in juvenile myoclonic epilepsy.An emerging role for bromodomain-containing proteins in chromatin regulation and transcriptional control of adipogenesis.The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis Inhibition of BET bromodomain targets genetically diverse glioblastoma Sex-specific behavioral traits in the Brd2 mouse model of juvenile myoclonic epilepsy Double-bromo and extraterminal (BET) domain proteins regulate dendrite morphology and mechanosensory function Bromodomain coactivators in cancer, obesity, type 2 diabetes, and inflammation Genetics and development of neural tube defects.Brd4 marks select genes on mitotic chromatin and directs postmitotic transcription A loss of function screen of identified genome-wide association study Loci reveals new genes controlling hematopoiesis The BET family member BRD4 interacts with OCT4 and regulates pluripotency gene expression.The bromodomain-containing gene BRD2 is regulated at transcription, splicing, and translation levels.The first bromodomain of the testis-specific double bromodomain protein Brdt is required for chromocenter organization that is modulated by genetic background Histone H4 acetylation and the epigenetic reader Brd4 are critical regulators of pluripotency in embryonic stem cells Targeting epigenetic regulations in cancer Development of neurodevelopmental disorders: a regulatory mechanism involving bromodomain-containing proteins BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses.When are the BET factors the most sensitive to bromodomain inhibitors?The role of the double bromodomain-containing BET genes during mammalian spermatogenesis.The double bromodomain protein Brd2 promotes B cell expansion and mitogenesis.BET inhibitors block pancreatic stellate cell collagen I production and attenuate fibrosis in vivo.Epigenetic Modulation of Stem Cells in Neurodevelopment: The Role of Methylation and Acetylation.Bromodomains as therapeutic targets.Bromodomains and their pharmacological inhibitors.Bromodomain and extraterminal (BET) proteins regulate biliary-driven liver regeneration.Mechanisms underlying the biological changes induced by isocitrate dehydrogenase-1 mutation in glioma cells.

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Double bromodomain-containing gene Brd2 is essential for embryonic development in mouse

http://www.wikidata.org/entity/Q37407183

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on April 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Double bromodomain-containing gene Brd2 is essential for embryonic development in mouse

@en

Double bromodomain-containing gene Brd2 is essential for embryonic development in mouse.

@nl

type

label

Double bromodomain-containing gene Brd2 is essential for embryonic development in mouse

@en

Double bromodomain-containing gene Brd2 is essential for embryonic development in mouse.

@nl

prefLabel

Double bromodomain-containing gene Brd2 is essential for embryonic development in mouse

@en

Double bromodomain-containing gene Brd2 is essential for embryonic development in mouse.

@nl

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Developmental Dynamics

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Double bromodomain-containing gene Brd2 is essential for embryonic development in mouse

@en

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David A Greenberg

http://www.w3.org/2001/XMLSchema#string

Debra J Wolgemuth

http://www.w3.org/2001/XMLSchema#string

Duancheng Wen

http://www.w3.org/2001/XMLSchema#string

Enyuan Shang

http://www.w3.org/2001/XMLSchema#string

Xiangyuan Wang

http://www.w3.org/2001/XMLSchema#string

P2860

The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription

BRD2 (RING3) is a probable major susceptibility gene for common juvenile myoclonic epilepsy

Interaction between acetylated MyoD and the bromodomain of CBP and/or p300

RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F

The bromodomain: a conserved sequence found in human, Drosophila and yeast proteins

Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation

The bromodomain: a chromatin-targeting module?

Activation-induced nuclear translocation of RING3

brahma: a regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2

Bromodomain: an acetyl-lysine binding domain

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908-917

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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10.1002/DVDY.21911

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4

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238

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2009-04-01T00:00:00Z

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24215088

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19301389

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2771124

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