Sponge-derived fijianolide polyketide class: further evaluation of their structural and cytotoxicity properties. - Wikidata - awgldk - TriplyDB

Sponge-derived fijianolide polyketide class: further evaluation of their structural and cytotoxicity properties.

Sponge-derived fijianolide polyketide class: further evaluation of their structural and cytotoxicity properties.

http://www.wikidata.org/entity/Q37409426

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Alternative and efficient extraction methods for marine-derived compounds Another Look at Pyrroloiminoquinone Alkaloids-Perspectives on Their Therapeutic Potential from Known Structures and Semisynthetic Analogues A selective account of effective paradigms and significant outcomes in the discovery of inspirational marine natural products.The marine sponge metabolite mycothiazole: a novel prototype mitochondrial complex I inhibitor.Natural product libraries to accelerate the high-throughput discovery of therapeutic leads Myxobacteria versus sponge-derived alkaloids: the bengamide family identified as potent immune modulating agents by scrutiny of LC-MS/ELSD libraries Using enzyme assays to evaluate the structure and bioactivity of sponge-derived meroterpenes Biostructural features of additional jasplakinolide (jaspamide) analogues.Woodylides A-C, new cytotoxic linear polyketides from the South China Sea sponge Plakortis simplex.Chemically diverse microtubule stabilizing agents initiate distinct mitotic defects and dysregulated expression of key mitotic kinases The aignopsanes, a new class of sesquiterpenes from selected chemotypes of the sponge Cacospongia mycofijiensis.Function-oriented synthesis: biological evaluation of laulimalide analogues derived from a last step cross metathesis diversification strategy.Taccalonolide binding to tubulin imparts microtubule stability and potent in vivo activity.Microtubule dynamics as a target in oncology.Interrogating the bioactive pharmacophore of the latrunculin chemotype by investigating the metabolites of two taxonomically unrelated sponges.Evaluating transition-metal-catalyzed transformations for the synthesis of laulimalide.Peloruside, laulimalide, and noscapine interactions with beta-tubulin.Microtubule stabilizing agents as potential treatment for Alzheimer's disease and related neurodegenerative tauopathies.Recent progress with microtubule stabilizers: new compounds, binding modes and cellular activities.Macrocycles as potential therapeutic agents in neglected diseases.Peloruside A: a lead non-taxoid-site microtubule-stabilizing agent with potential activity against cancer, neurodegeneration, and autoimmune disease.Assessing pressurized liquid extraction for the high-throughput extraction of marine-sponge-derived natural products.Vinylphosphonium and 2-aminovinylphosphonium salts - preparation and applications in organic synthesis.An Asymmetric Tandem Conjugative Addition-Intramolecular Cyclisation Process to Provide Functionalised 3,6-Dihydropyrans and 4,5-Epoxytetrahydropyrans

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P2860

Sponge-derived fijianolide polyketide class: further evaluation of their structural and cytotoxicity properties.

http://www.wikidata.org/entity/Q37409426

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 10 July 2007

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Sponge-derived fijianolide pol ...... l and cytotoxicity properties.

@en

Sponge-derived fijianolide pol ...... l and cytotoxicity properties.

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type

label

Sponge-derived fijianolide pol ...... l and cytotoxicity properties.

@en

Sponge-derived fijianolide pol ...... l and cytotoxicity properties.

@nl

prefLabel

Sponge-derived fijianolide pol ...... l and cytotoxicity properties.

@en

Sponge-derived fijianolide pol ...... l and cytotoxicity properties.

@nl

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Sponge-derived fijianolide pol ...... l and cytotoxicity properties.

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P2093

Balanehru Subramanian

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Brandon I Morinaka

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Frederick A Valeriote

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Joseph Media

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Karen Tenney

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Kimberly N White

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Phillip Crews

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Robert H Cichewicz

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Susan L Mooberry

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Taro Amagata

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P2860

Structures and cytotoxic properties of sponge-derived bisannulated acridines.

Lethal and sublethal effects of withanolides from Salpichroa origanifolia and analogues on Ceratitis capitata.

Microtubule-stabilizing agents based on designed laulimalide analogues.

A new paradigm for the development of anticancer agents from natural products

Microtubule-stabilizing marine metabolite laulimalide and its derivatives: synthetic approaches and antitumor activity.

A reassignment of (-)-mycothiazole and the isolation of a related diol

Tedanolide C: a potent new 18-membered-ring cytotoxic macrolide isolated from the Papua New Guinea marine sponge Ircinia sp.

Design, synthesis and biological evaluation of novel, simplified analogues of laulimalide: modification of the side chain.

Peloruside A does not bind to the taxoid site on beta-tubulin and retains its activity in multidrug-resistant cell lines.

Synthesis and biological evaluation of (-)-laulimalide analogues.

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3795-3803

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10.1021/JM070410Z

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