Blockade of SDF-1 after irradiation inhibits tumor recurrences of autochthonous brain tumors in rats.
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Impacts of Ionizing Radiation on the Different Compartments of the Tumor MicroenvironmentAptamers: A promising chemical antibody for cancer therapyTherapies targeting cancer stem cells: Current trends and future challengesVasculogenesis: a crucial player in the resistance of solid tumours to radiotherapyTherapeutic aptamers: developmental potential as anticancer drugsCXCL12 modulation of CXCR4 and CXCR7 activity in human glioblastoma stem-like cells and regulation of the tumor microenvironment.Selection of Nucleic Acid Aptamers Targeting Tumor Cell-Surface Protein BiomarkersDistinct luminal-type mammary carcinomas arise from orthotopic Trp53-null mammary transplantation of juvenile versus adult mice.Hypoxia-inducible factor 1α (HIF-1α) and reactive oxygen species (ROS) mediates radiation-induced invasiveness through the SDF-1α/CXCR4 pathway in non-small cell lung carcinoma cells.Recurrence of glioblastoma after radio-chemotherapy is associated with an angiogenic switch to the CXCL12-CXCR4 pathway.Radiation-induced lung damage promotes breast cancer lung-metastasis through CXCR4 signaling.Targeting CXCR4 by a selective peptide antagonist modulates tumor microenvironment and microglia reactivity in a human glioblastoma modelColony stimulating factor 1 receptor inhibition delays recurrence of glioblastoma after radiation by altering myeloid cell recruitment and polarization.SDF-1 Blockade Enhances Anti-VEGF Therapy of Glioblastoma and Can Be Monitored by MRI.Inhibition of CXCR7 extends survival following irradiation of brain tumours in mice and rats.CXCR4 increases in-vivo glioma perivascular invasion, and reduces radiation induced apoptosis: A genetic knockdown study.Aptamers as targeted therapeutics: current potential and challenges.CXCL12/CXCR4: a symbiotic bridge linking cancer cells and their stromal neighbors in oncogenic communication networks.Irradiation induces glioblastoma cell senescence and senescence-associated secretory phenotype.The Promise of Targeting Macrophages in Cancer Therapy.(68)Ga-Pentixafor-PET/CT for Imaging of Chemokine Receptor 4 Expression in Glioblastoma.M2 macrophages are more resistant than M1 macrophages following radiation therapy in the context of glioblastoma.Getting more out of radiation therapy in glioblastoma.Inhibition of SDF-1-induced migration of oncogene-driven myeloid leukemia by the L-RNA aptamer (Spiegelmer), NOX-A12, and potentiation of tyrosine kinase inhibition.Multifaceted C-X-C Chemokine Receptor 4 (CXCR4) Inhibition Interferes with Anti-Vascular Endothelial Growth Factor Therapy-Induced Glioma Dissemination.Therapeutic targeting of tumor-associated macrophages and microglia in glioblastoma.The role of macrophage phenotype in regulating the response to radiation therapy.Aptamer Therapeutics in Cancer: Current and Future.CXCR7 Targeting and Its Major Disease Relevance.Microglia/Astrocytes-Glioblastoma Crosstalk: Crucial Molecular Mechanisms and Microenvironmental Factors
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Blockade of SDF-1 after irradiation inhibits tumor recurrences of autochthonous brain tumors in rats.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 10 December 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Blockade of SDF-1 after irradi ...... hthonous brain tumors in rats.
@en
Blockade of SDF-1 after irradi ...... hthonous brain tumors in rats.
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Blockade of SDF-1 after irradi ...... hthonous brain tumors in rats.
@en
Blockade of SDF-1 after irradi ...... hthonous brain tumors in rats.
@nl
prefLabel
Blockade of SDF-1 after irradi ...... hthonous brain tumors in rats.
@en
Blockade of SDF-1 after irradi ...... hthonous brain tumors in rats.
@nl
P2093
P2860
P356
P1433
P1476
Blockade of SDF-1 after irradi ...... hthonous brain tumors in rats.
@en
P2093
Anna Kruschinski
Dirk Zboralski
Fred Lartey
J Martin Brown
Jason Stafford
Lawrence Recht
Milton Merchant
Reem Alomran
Shie-Chau Liu
Stefan Zöllner
P2860
P356
10.1093/NEUONC/NOT149
P577
2013-12-10T00:00:00Z