The membrane protein ATPase class I type 8B member 1 signals through protein kinase C zeta to activate the farnesoid X receptor. - Wikidata - awgldk - TriplyDB

The membrane protein ATPase class I type 8B member 1 signals through protein kinase C zeta to activate the farnesoid X receptor.

The membrane protein ATPase class I type 8B member 1 signals through protein kinase C zeta to activate the farnesoid X receptor.

http://www.wikidata.org/entity/Q37415558

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Dynamic regulation of cardiolipin by the lipid pump Atp8b1 determines the severity of lung injury in experimental pneumonia Differential effects of progressive familial intrahepatic cholestasis type 1 and benign recurrent intrahepatic cholestasis type 1 mutations on canalicular localization of ATP8B1 Cholestatic liver disease in children Bile acids are nutrient signaling hormones Bridging cell surface receptor with nuclear receptors in control of bile acid homeostasis The role of inflammation in cholestasis: clinical and basic aspects Direct methylation of FXR by Set7/9, a lysine methyltransferase, regulates the expression of FXR target genes Phospholipase D2 mediates signaling by ATPase class I type 8B membrane 1 P4 ATPases: flippases in health and disease Poly(ADP-ribose) polymerase 1 promotes oxidative-stress-induced liver cell death via suppressing farnesoid X receptor α.Survey of phosphorylation near drug binding sites in the Protein Data Bank (PDB) and their effects.Progressive familial intrahepatic cholestasis.ATPase Class I Type 8B Member 1 and protein kinase C zeta induce the expression of the canalicular bile salt export pump in human hepatocytes.Bile acids regulate hepatic gluconeogenic genes and farnesoid X receptor via G(alpha)i-protein-coupled receptors and the AKT pathway.Ileal apical Na+-dependent bile acid transporter ASBT is upregulated in rats with diabetes mellitus induced by low doses of streptozotocin.ATP8B1 gene expression is driven by a housekeeping-like promoter independent of bile acids and farnesoid X receptor.Regulation of FXR transcriptional activity in health and disease: Emerging roles of FXR cofactors and post-translational modifications Bile acid pool dynamics in progressive familial intrahepatic cholestasis with partial external bile diversion.ATP8B1 deficiency disrupts the bile canalicular membrane bilayer structure in hepatocytes, but FXR expression and activity are maintained.FXR and PXR: potential therapeutic targets in cholestasis.General molecular biology and architecture of nuclear receptors.Bile acid signal-induced phosphorylation of small heterodimer partner by protein kinase Cζ is critical for epigenomic regulation of liver metabolic genes Bile acids as regulatory molecules.Modulation of ileal apical Na+-dependent bile acid transporter ASBT by protein kinase C c-Fos mediates repression of the apical sodium-dependent bile acid transporter by fibroblast growth factor-19 in mice Biochemical and cellular functions of P4 ATPases.Control of nuclear receptor activities in metabolism by post-translational modifications.miR-33 controls the expression of biliary transporters, and mediates statin- and diet-induced hepatotoxicity Posttranslational Modifications of Lipid-Activated Nuclear Receptors: Focus on Metabolism.Knockdown of ATP8B1 expression leads to specific downregulation of the bile acid sensor FXR in HepG2 cells: effect of the FXR agonist GW4064.Liver disease without flipping: new functions of ATP8B1, the protein affected in familial intrahepatic cholestasis type 1.Expression and localization of atypical PKC isoforms in liver parenchymal cells.Assessment of ATP8B1 Deficiency in Pediatric Patients With Cholestasis Using Peripheral Blood Monocyte-Derived Macrophages.Bile acids as global regulators of hepatic nutrient metabolism

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The membrane protein ATPase class I type 8B member 1 signals through protein kinase C zeta to activate the farnesoid X receptor.

http://www.wikidata.org/entity/Q37415558

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on December 2008

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

The membrane protein ATPase cl ...... vate the farnesoid X receptor.

@en

The membrane protein ATPase cl ...... vate the farnesoid X receptor.

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type

label

The membrane protein ATPase cl ...... vate the farnesoid X receptor.

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The membrane protein ATPase cl ...... vate the farnesoid X receptor.

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prefLabel

The membrane protein ATPase cl ...... vate the farnesoid X receptor.

@en

The membrane protein ATPase cl ...... vate the farnesoid X receptor.

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The membrane protein ATPase cl ...... vate the farnesoid X receptor.

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An-Qiang Sun

http://www.w3.org/2001/XMLSchema#string

Benjamin L Shneider

http://www.w3.org/2001/XMLSchema#string

Frank Y Chen

http://www.w3.org/2001/XMLSchema#string

Frederick J Suchy

http://www.w3.org/2001/XMLSchema#string

Irwin Arias

http://www.w3.org/2001/XMLSchema#string

Kenneth D R Setchell

http://www.w3.org/2001/XMLSchema#string

Meena Ananthanarayanan

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Natarajan Balasubramaniyan

http://www.w3.org/2001/XMLSchema#string

Tamara Frankenberg

http://www.w3.org/2001/XMLSchema#string

Tamir Miloh

http://www.w3.org/2001/XMLSchema#string

P2860

A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis

Identification of a nuclear receptor for bile acids

Bile acids: natural ligands for an orphan nuclear receptor

Reduced hepatic expression of farnesoid X receptor in hereditary cholestasis associated to mutation in ATP8B1

Altered hepatobiliary gene expressions in PFIC1: ATP8B1 gene defect is associated with CFTR downregulation

A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR

Structural basis for bile acid binding and activation of the nuclear receptor FXR

A subfamily of P-type ATPases with aminophospholipid transporting activity.

The bile acid taurochenodeoxycholate activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

P304

1896-1905

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scholarly article

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10.1002/HEP.22431

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P407

P433

6

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48

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2008-12-01T00:00:00Z

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23139041

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18668687

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2774894

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