Endogenous bile acids are ligands for the nuclear receptor FXR/BAR - Wikidata - awgldk - TriplyDB

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

http://www.wikidata.org/entity/Q28198990

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Bile acids as endogenous etiologic agents in gastrointestinal cancer Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis Identification of farnesoid X receptor beta as a novel mammalian nuclear receptor sensing lanosterol Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearance Chronic diarrhea due to excessive bile acid synthesis and not defective ileal transport: a new syndrome of defective fibroblast growth factor 19 release Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXR Potent stimulation of fibroblast growth factor 19 expression in the human ileum by bile acids The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity Bile acid transporters in health and disease Bile acids inhibit duodenal secretin expression via orphan nuclear receptor small heterodimer partner (SHP)Bile salts of vertebrates: structural variation and possible evolutionary significance Molecular mechanisms involved in farnesol-induced apoptosis Bile acids: regulation of synthesis Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice Differential modulation of cellular death and survival pathways by conjugated bile acids Gut Microbiota Modification: Another Piece in the Puzzle of the Benefits of Physical Exercise in Health?Bile acid receptors and nonalcoholic fatty liver disease Bile acids: emerging role in management of liver diseases Cross-talk between bile acids and gastrointestinal tract for progression and development of cancer and its therapeutic implications Bile acids are nutrient signaling hormones Nuclear receptors in bone physiology and diseases Bile acid metabolism and signaling FXR signaling in the enterohepatic system Bile acids, obesity, and the metabolic syndrome Hepatic farnesoid X-receptor isoforms α2 and α4 differentially modulate bile salt and lipoprotein metabolism in mice Identification of a potent synthetic FXR agonist with an unexpected mode of binding and activation The antiparasitic drug ivermectin is a novel FXR ligand that regulates metabolism Fatty liver diseases, bile acids, and FXR Gut Microbiota and Host Reaction in Liver Diseases Bile acid nuclear receptor FXR and digestive system diseases Role of farnesoid X receptor and bile acids in alcoholic liver disease The nuclear receptor FXR is expressed in pancreatic beta-cells and protects human islets from lipotoxicity The amino acid residues asparagine 354 and isoleucine 372 of human farnesoid X receptor confer the receptor with high sensitivity to chenodeoxycholate Key discoveries in bile acid chemistry and biology and their clinical applications: history of the last eight decades Farnesoid X receptor: a master regulator of hepatic triglyceride and glucose homeostasis Farnesoid X receptor: from medicinal chemistry to clinical applications The nuclear receptor for bile acids, FXR, transactivates human organic solute transporter-alpha and -beta genes Alpha 1-fetoprotein transcription factor is required for the expression of sterol 12alpha -hydroxylase, the specific enzyme for cholic acid synthesis. Potential role in the bile acid-mediated regulation of gene transcription Farnesol stimulates differentiation in epidermal keratinocytes via PPARalpha

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P2860

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

http://www.wikidata.org/entity/Q28198990

description

1999 nî lūn-bûn

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1999 թուականի Մայիսին հրատարակուած գիտական յօդուած

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1999 թվականի մայիսին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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name

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

@ast

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

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Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

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type

label

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

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Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

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Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

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prefLabel

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

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Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

@en

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

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Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

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B M Forman

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H Wang

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J Chen

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K Hollister

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L C Sowers

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scholarly article

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10.1016/S1097-2765(00)80348-2

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