Fatty acid hydroperoxides support cytochrome P450 2S1-mediated bioactivation of benzo[a]pyrene-7,8-dihydrodiol.
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Cytochrome P4502S1: a novel monocyte/macrophage fatty acid epoxygenase in human atherosclerotic plaquesHuman CYP2S1 metabolizes cyclooxygenase- and lipoxygenase-derived eicosanoidsContributions of human enzymes in carcinogen metabolismCharacterizing proteins of unknown function: orphan cytochrome p450 enzymes as a paradigm.Efficient hypoxic activation of the anticancer agent AQ4N by CYP2S1 and CYP2W1.Cytochrome P450 2S1 is reduced by NADPH-cytochrome P450 reductase.The anticancer drug ellipticine activated with cytochrome P450 mediates DNA damage determining its pharmacological efficiencies: studies with rats, Hepatic Cytochrome P450 Reductase Null (HRN™) mice and pure enzymes.Increases in plasma trans-EETs and blood pressure reduction in spontaneously hypertensive rats.Orphans in the human cytochrome P450 superfamily: approaches to discovering functions and relevance in pharmacology.Cytochrome P450 2S1 depletion enhances cell proliferation and migration in bronchial epithelial cells, in part, through modulation of prostaglandin E(2) synthesis.Generation and characterization of a novel Cyp2a(4/5)bgs-null mouse modelCytochromes p450 and skin cancer: role of local endocrine pathways.Functional characterization of human cytochrome P450 2S1 using a synthetic gene-expressed protein in Escherichia coli.The role of antioxidants and pro-oxidants in colon cancer.Vitamin C activation of the biosynthesis of epoxyeicosatrienoic acids.Approaches to deorphanization of human and microbial cytochrome P450 enzymes.Extrahepatic metabolism at the body's internal-external interfaces.Heterologous expression of human cytochrome P450 2S1 in Escherichia coli and investigation of its role in metabolism of benzo[a]pyrene and ellipticine.Reduction of aromatic and heterocyclic aromatic N-hydroxylamines by human cytochrome P450 2S1.Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
P2860
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P2860
Fatty acid hydroperoxides support cytochrome P450 2S1-mediated bioactivation of benzo[a]pyrene-7,8-dihydrodiol.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 27 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Fatty acid hydroperoxides supp ...... enzo[a]pyrene-7,8-dihydrodiol.
@en
Fatty acid hydroperoxides supp ...... enzo[a]pyrene-7,8-dihydrodiol.
@nl
type
label
Fatty acid hydroperoxides supp ...... enzo[a]pyrene-7,8-dihydrodiol.
@en
Fatty acid hydroperoxides supp ...... enzo[a]pyrene-7,8-dihydrodiol.
@nl
prefLabel
Fatty acid hydroperoxides supp ...... enzo[a]pyrene-7,8-dihydrodiol.
@en
Fatty acid hydroperoxides supp ...... enzo[a]pyrene-7,8-dihydrodiol.
@nl
P2093
P2860
P356
P1476
Fatty acid hydroperoxides supp ...... enzo[a]pyrene-7,8-dihydrodiol.
@en
P2093
Erin L Hsu
Oliver Hankinson
Peter H Bui
P2860
P304
P356
10.1124/MOL.109.057760
P577
2009-08-27T00:00:00Z