Functional characterization of human cytochrome P450 2S1 using a synthetic gene-expressed protein in Escherichia coli.
about
Human CYP2S1 metabolizes cyclooxygenase- and lipoxygenase-derived eicosanoidsContributions of human enzymes in carcinogen metabolismA transcriptomic approach to elucidate the physiological significance of human cytochrome P450 2S1 in bronchial epithelial cellsCharacterizing proteins of unknown function: orphan cytochrome p450 enzymes as a paradigm.Achaete-scute homologue-1 tapers neuroendocrine cell differentiation in lungs after exposure to naphthaleneEfficient hypoxic activation of the anticancer agent AQ4N by CYP2S1 and CYP2W1.Cytochrome P450 2S1 is reduced by NADPH-cytochrome P450 reductase.The anticancer drug ellipticine activated with cytochrome P450 mediates DNA damage determining its pharmacological efficiencies: studies with rats, Hepatic Cytochrome P450 Reductase Null (HRN™) mice and pure enzymes.Orphans in the human cytochrome P450 superfamily: approaches to discovering functions and relevance in pharmacology.Cytochrome P450 2S1 depletion enhances cell proliferation and migration in bronchial epithelial cells, in part, through modulation of prostaglandin E(2) synthesis.Species difference in the regulation of cytochrome P450 2S1: lack of induction in rats by the aryl hydrocarbon receptor agonist PCB126Cytochromes p450 and skin cancer: role of local endocrine pathways.Fatty acid hydroperoxides support cytochrome P450 2S1-mediated bioactivation of benzo[a]pyrene-7,8-dihydrodiol.Approaches to deorphanization of human and microbial cytochrome P450 enzymes.Cytochrome P450-mediated pulmonary metabolism of carcinogens: regulation and cross-talk in lung carcinogenesis.Peroxygenase reactions catalyzed by cytochromes P450.Heterologous expression of human cytochrome P450 2S1 in Escherichia coli and investigation of its role in metabolism of benzo[a]pyrene and ellipticine.Loss of PHD3 in myeloid cells dampens the inflammatory response and fibrosis after hind-limb ischemia.Reduction of aromatic and heterocyclic aromatic N-hydroxylamines by human cytochrome P450 2S1.Heterologous expression of human cytochromes P450 2D6 and CYP3A4 in Escherichia coli and their functional characterization.Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
P2860
Q28298062-1B11C86E-4B9F-460D-BF7A-0D0058F54B27Q30520640-2EF0EA42-C9B3-4380-B237-3B37D2010D92Q31144501-9F6198A8-6665-47E8-A182-0AF04B799356Q33953907-973222E6-FF2C-421E-8352-4E904C7E68CAQ34071999-601BEA8A-080D-43FB-B090-751F4693BC0BQ34127983-CC2DAFB2-5C3B-498F-A30A-FD27E2135D0EQ35002471-9F646F18-4090-481F-AC17-D24139ECF68DQ35016427-6315784E-9B34-49F4-A55D-76D745FFA0C0Q35122778-712F65A8-1E0C-4619-9AB1-9DB5C55EAEF5Q36335457-3087448F-F0D8-440F-80CC-1D751BF12952Q36588312-AD507653-0A6A-4130-A7E8-71D21D96C755Q37088368-CD2F124B-CE9E-462D-ABBA-C5D3D945BAB3Q37415810-9C606ED8-9402-4498-B62D-EEAA987F6758Q37759731-7693E3CE-BA7F-482D-B9A1-86DDC545538AQ37811619-0431F46B-EA14-455C-8964-018E544A6098Q38185537-691D1000-FE3B-4ECE-AE30-B8BF1FA2E664Q40062685-6B852EBE-CF90-4D29-ADA7-F1152C6FE072Q41169352-EDD1D441-A29A-473C-A5D0-34AD601A5339Q42112553-13809E45-CB9C-4409-B458-CD262ED7CC6DQ55055040-22C78C6B-D980-4C4C-9B6E-FA20B0F9773CQ57095660-800B5256-76F7-46FE-BD1D-A647F8DB7BF8
P2860
Functional characterization of human cytochrome P450 2S1 using a synthetic gene-expressed protein in Escherichia coli.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 27 August 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Functional characterization of ...... d protein in Escherichia coli.
@en
Functional characterization of ...... d protein in Escherichia coli.
@nl
type
label
Functional characterization of ...... d protein in Escherichia coli.
@en
Functional characterization of ...... d protein in Escherichia coli.
@nl
prefLabel
Functional characterization of ...... d protein in Escherichia coli.
@en
Functional characterization of ...... d protein in Escherichia coli.
@nl
P2860
P356
P1476
Functional characterization of ...... d protein in Escherichia coli.
@en
P2093
Oliver Hankinson
Peter H Bui
P2860
P304
P356
10.1124/MOL.109.057752
P577
2009-08-27T00:00:00Z