T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance.
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The human cytomegalovirus UL11 protein interacts with the receptor tyrosine phosphatase CD45, resulting in functional paralysis of T cellsT cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in miceCyclin-dependent kinase 5 activity is required for T cell activation and induction of experimental autoimmune encephalomyelitisHeterogeneity of white adipose tissue: molecular basis and clinical implicationsComparative Anatomy of Phagocytic and Immunological SynapsesDouble-negative T cells during HIV/SIV infections: potential pinch hitters in the T-cell lineupMultifunctional double-negative T cells in sooty mangabeys mediate T-helper functions irrespective of SIV infectionNovel autophosphorylation sites of Src family kinases regulate kinase activity and SH2 domain-binding capacityA live imaging cell motility screen identifies prostaglandin E2 as a T cell stop signal antagonistTime-Dependent Regulation of IL-2R α-Chain (CD25) Expression by TCR Signal Strength and IL-2-Induced STAT5 Signaling in Activated Human Blood T LymphocytesInhibition of the plasma membrane Ca2+ pump by CD44 receptor activation of tyrosine kinases increases the action potential afterhyperpolarization in sensory neuronsMolecular cloning and characterization of lymphocyte cell kinase from humphead snapper (Lutjanus sanguineus).Isolation of monobodies that bind specifically to the SH3 domain of the Fyn tyrosine protein kinase.Nutrigenetics and nutrigenomics insights into diabetes etiopathogenesis.Hedgehog signaling controls T cell killing at the immunological synapse.Intrinsic Photosensitivity Enhances Motility of T Lymphocytes.Roles of the Src tyrosine kinases Lck and Fyn in regulating gammadeltaTCR signal strengthTOM1L is involved in a novel signaling pathway important for the IL-2 production in Jurkat T cells stimulated by CD3/CD28 co-ligation.T cell receptor signal initiation induced by low-grade stimulation requires the cooperation of LAT in human T cells.Hierarchical graphs for rule-based modeling of biochemical systemsInsufficient deactivation of the protein tyrosine kinase lck amplifies T-cell responsiveness in acute coronary syndromeGene expression analyses of immune responses in Atlantic salmon during early stages of infection by salmon louse (Lepeophtheirus salmonis) revealed bi-phasic responses coinciding with the copepod-chalimus transition.Targeted therapies of the LKB1/AMPK pathway for the treatment of insulin resistanceCentrosome docking at the immunological synapse is controlled by Lck signaling.Genetic deficiency of Syk protects mice from autoantibody-induced arthritis.HIV-1 Nef: a multifaceted modulator of T cell receptor signaling.Non-catalytic functions of Pyk2 and Fyn regulate late stage adhesion in human T cells.Structural requirements for cub domain containing protein 1 (CDCP1) and Src dependent cell transformationSuppressor of cytokine signaling 1 interacts with oncogenic lymphocyte-specific protein tyrosine kinase.Interferon γ limits the effectiveness of melanoma peptide vaccines.Progress towards the development of SH2 domain inhibitors.Human kinome analysis reveals novel kinases contributing to virus infection and retinoic-acid inducible gene I-induced type I and type III IFN gene expression.Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptorThe role of tyrosine kinases in systemic lupus erythematosus and their potential as therapeutic targets.Characterization of CEBPA mutations and promoter hypermethylation in pediatric acute myeloid leukemia.Immunodeficiency and immune dysregulation associated with proximal defects of T cell receptor signaling.Coinfection with Streptococcus pneumoniae negatively modulates the size and composition of the ongoing influenza-specific CD8⁺ T cell responseROS-DET: robust detector of switching mechanisms in gene expressionA model of an integrated immune system pathway in Homo sapiens and its interaction with superantigen producing expression regulatory pathway in Staphylococcus aureus: comparing behavior of pathogen perturbed and unperturbed pathwayWide-scale quantitative phosphoproteomic analysis reveals that cold treatment of T cells closely mimics soluble antibody stimulation.
P2860
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P2860
T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
T-cell receptor proximal signa ...... ifferentiation, and tolerance.
@en
T-cell receptor proximal signa ...... ifferentiation, and tolerance.
@nl
type
label
T-cell receptor proximal signa ...... ifferentiation, and tolerance.
@en
T-cell receptor proximal signa ...... ifferentiation, and tolerance.
@nl
prefLabel
T-cell receptor proximal signa ...... ifferentiation, and tolerance.
@en
T-cell receptor proximal signa ...... ifferentiation, and tolerance.
@nl
P50
P1476
T-cell receptor proximal signa ...... ifferentiation, and tolerance.
@en
P2093
Andrew Filby
Ihjaaz Qureshi
P356
10.1111/J.1600-065X.2008.00745.X
P577
2009-03-01T00:00:00Z