Phase I study of SU5416, a small molecule inhibitor of the vascular endothelial growth factor receptor (VEGFR) in refractory pediatric central nervous system tumors.
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Brainstem Glioma in AdultsSU5416, a VEGF receptor inhibitor and ligand of the AHR, represents a new alternative for immunomodulationUnexpected neuronal protection of SU5416 against 1-Methyl-4-phenylpyridinium ion-induced toxicity via inhibiting neuronal nitric oxide synthaseAn operational perspective of challenging statistical dogma while establishing a modern, secure distributed data management and imaging transport system: the Pediatric Brain Tumor Consortium phase I experience.Childhood brain tumors: epidemiology, current management and future directions.Buyang huanwu decoction promotes angiogenesis via vascular endothelial growth factor receptor-2 activation through the PI3K/Akt pathway in a mouse model of intracerebral hemorrhage.Development of a biomimetic peptide derived from collagen IV with anti-angiogenic activity in breast cancerClinical development of VEGF signaling pathway inhibitors in childhood solid tumors.Improving the outcome for children with cancer: Development of targeted new agents.Preclinical Modeling of Tumor Growth and Angiogenesis Inhibition to Describe Pazopanib Clinical Effects in Renal Cell Carcinoma.The VEGF pathway in cancer and disease: responses, resistance, and the path forward.Antiangiogenic (metronomic) chemotherapy for brain tumors: current and future perspectives.Antiangiogenic therapy and mechanisms of tumor resistance in malignant glioma.New anti-angiogenic strategies in pediatric solid malignancies: agents and biomarkers of a near future.Molecular biology of pediatric brain tumors and impact on novel therapies.A comparison of safety and efficacy of cytotoxic versus molecularly targeted drugs in pediatric phase I solid tumor oncology trials.Incisor degeneration in rats induced by vascular endothelial growth factor/fibroblast growth factor receptor tyrosine kinase inhibition.Proceedings of the diffuse intrinsic pontine glioma (DIPG) Toronto Think Tank: advancing basic and translational research and cooperation in DIPG.Inhibition of fibroblast growth factor receptor with AZD4547 mitigates juvenile nasopharyngeal angiofibroma.Bevacizumab use in disseminated choroid plexus papilloma.Feasibility and clinical integration of molecular profiling for target identification in pediatric solid tumors.
P2860
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P2860
Phase I study of SU5416, a small molecule inhibitor of the vascular endothelial growth factor receptor (VEGFR) in refractory pediatric central nervous system tumors.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on February 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Phase I study of SU5416, a sma ...... central nervous system tumors.
@en
Phase I study of SU5416, a sma ...... central nervous system tumors.
@nl
type
label
Phase I study of SU5416, a sma ...... central nervous system tumors.
@en
Phase I study of SU5416, a sma ...... central nervous system tumors.
@nl
prefLabel
Phase I study of SU5416, a sma ...... central nervous system tumors.
@en
Phase I study of SU5416, a sma ...... central nervous system tumors.
@nl
P2093
P2860
P50
P356
P1476
Phase I study of SU5416, a sma ...... central nervous system tumors.
@en
P2093
Anu Banerjee
Dana Wallace
Ian Pollack
James M Boyett
Jeffrey G Supko
Larry E Kun
Pediatric Brain Tumor Consortium
Peter Phillips
Roger Packer
Russ Geyer
P2860
P304
P356
10.1002/PBC.21873
P577
2009-02-01T00:00:00Z