Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases.
about
Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAsCRISPR/Cas9: Implications for Modeling and Therapy of Neurodegenerative DiseasesSite-Specific Integration of Exogenous Genes Using Genome Editing Technologies in ZebrafishA new age in functional genomics using CRISPR/Cas9 in arrayed library screeningCRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseasesInduced pluripotent stem cells in hematology: current and future applicationsTargeted genome editing in primate embryosThe CRISPR system can correct or modify the expression of genes responsible for hereditary diseasesCRISPR/Cas9-induced knockout and knock-in mutations in Chlamydomonas reinhardtiiBATCH-GE: Batch analysis of Next-Generation Sequencing data for genome editing assessment.Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins.Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA.Studying disorders of vertebrate iron and heme metabolism using zebrafish.Next-generation mammalian genetics toward organism-level systems biologyCRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome.In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuniTargeted inversion and reversion of the blood coagulation factor 8 gene in human iPS cells using TALENsBacterial CRISPR: accomplishments and prospects.Targeted gene knockout in chickens mediated by TALENsFish is Fish: the use of experimental model species to reveal causes of skeletal diversity in evolution and diseaseSomatic mosaicism and allele complexity induced by CRISPR/Cas9 RNA injections in mouse zygotes.Efficient gene targeting in golden Syrian hamsters by the CRISPR/Cas9 system.A mouse geneticist's practical guide to CRISPR applications.From the bush to the bench: the annual Nothobranchius fishes as a new model system in biology.Generation of knock-in primary human T cells using Cas9 ribonucleoproteins.CRISPR/Cas9: An inexpensive, efficient loss of function tool to screen human disease genes in Xenopus.Structure and Engineering of Francisella novicida Cas9.Detailed phenotypic and molecular analyses of genetically modified mice generated by CRISPR-Cas9-mediated editingCRISPR-engineered mosaicism rapidly reveals that loss of Kcnj13 function in mice mimics human disease phenotypes.The same but different: worms reveal the pervasiveness of developmental system drift.sgRNAcas9: a software package for designing CRISPR sgRNA and evaluating potential off-target cleavage sites.Efficient gene knockout in goats using CRISPR/Cas9 system.IFT46 plays an essential role in cilia developmentCloning-free CRISPR/Cas system facilitates functional cassette knock-in in mice.Efficient Multiple Genome Modifications Induced by the crRNAs, tracrRNA and Cas9 Protein Complex in Zebrafish.Is mouse embryonic stem cell technology obsolete?Pervasive Genotypic Mosaicism in Founder Mice Derived from Genome Editing through Pronuclear InjectionRNA-guided genome editing in Drosophila with the purified Cas9 proteinMultiplex Conditional Mutagenesis Using Transgenic Expression of Cas9 and sgRNAsA Vector with a Single Promoter for In Vitro Transcription and Mammalian Cell Expression of CRISPR gRNAs.
P2860
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P2860
Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh
2013年學術文章
@zh-hant
name
Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases.
@en
Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases.
@nl
type
label
Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases.
@en
Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases.
@nl
prefLabel
Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases.
@en
Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases.
@nl
P2093
P2860
P356
P1433
P1476
Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases.
@en
P2093
Cheol-Hee Kim
Han-Woong Lee
Hyun-Taek Kim
Jaehoon Lee
Jisun Jeon
Jong Min Kim
Jung-Hwa Choi
Young Ho Ban
Young Hoon Sung
P2860
P304
P356
10.1101/GR.163394.113
P577
2013-11-19T00:00:00Z