Clodronate acts on human osteoclastic cell proliferation, differentiation and function in a bioreversible manner. - Wikidata - awgldk - TriplyDB

Clodronate acts on human osteoclastic cell proliferation, differentiation and function in a bioreversible manner.

Clodronate acts on human osteoclastic cell proliferation, differentiation and function in a bioreversible manner.

http://www.wikidata.org/entity/Q37430521

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Clodronate acts on human osteoclastic cell proliferation, differentiation and function in a bioreversible manner.

http://www.wikidata.org/entity/Q37430521

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article científic

@ca

article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on May 2007

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Clodronate acts on human osteo ...... ion in a bioreversible manner.

@en

Clodronate acts on human osteo ...... ion in a bioreversible manner.

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type

label

Clodronate acts on human osteo ...... ion in a bioreversible manner.

@en

Clodronate acts on human osteo ...... ion in a bioreversible manner.

@nl

prefLabel

Clodronate acts on human osteo ...... ion in a bioreversible manner.

@en

Clodronate acts on human osteo ...... ion in a bioreversible manner.

@nl

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Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases

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Clodronate acts on human osteo ...... ion in a bioreversible manner.

@en

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Alessandro Franchi

http://www.w3.org/2001/XMLSchema#string

Anna Maria Carossino

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Annalisa Tanini

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Gianluca Bartolucci

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Giuseppe Leone

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Giuseppe Pieraccini

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Gloriano Moneti

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Lisa Simi

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Marco Orfei

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Maria Luisa Brandi

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P2860

Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase

Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates.

Nitrogen-bisphosphonates block retinoblastoma phosphorylation and cell growth by inhibiting the cholesterol biosynthetic pathway in a keratinocyte model for esophageal irritation.

Bisphosphonates: from the laboratory to the clinic and back again.

The role of geranylgeranylation in bone resorption and its suppression by bisphosphonates in fetal bone explants in vitro: A clue to the mechanism of action of nitrogen-containing bisphosphonates.

Protein geranylgeranylation is required for osteoclast formation, function, and survival: inhibition by bisphosphonates and GGTI-298.

Cellular and molecular mechanisms of action of bisphosphonates.

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Bisphosphonates directly inhibit the bone resorption activity of isolated avian osteoclasts in vitro.

Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5'-(beta, gamma-dichloromethylene) triphosphate, by mammalian cells in vitro.

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146-155

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2007-05-01T00:00:00Z

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22461215

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2781243

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