Structure-activity relationship study of indole-2-carboxamides identifies a potent allosteric modulator for the cannabinoid receptor 1 (CB1).
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Minireview: From the bench, toward the clinic: therapeutic opportunities for cannabinoid receptor modulationEndogenous vs Exogenous Allosteric Modulators in GPCRs: A dispute for shuttling CB1 among different membrane microenvironments.Computational analysis of the CB1 carboxyl-terminus in the receptor-G protein complexDiarylureas as allosteric modulators of the cannabinoid CB1 receptor: structure-activity relationship studies on 1-(4-chlorophenyl)-3-{3-[6-(pyrrolidin-1-yl)pyridin-2-yl]phenyl}urea (PSNCBAM-1).Optimization of chemical functionalities of indole-2-carboxamides to improve allosteric parameters for the cannabinoid receptor 1 (CB1).Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s).Allosteric Modulation: An Alternate Approach Targeting the Cannabinoid CB1 Receptor.Systematic discovery of molecular probes targeting multiple non-orthosteric and spatially distinct sites in the botulinum neurotoxin subtype A (BoNT/A).Structure-activity relationships of substituted 1H-indole-2-carboxamides as CB1 receptor allosteric modulators.Synthesis and biological evaluation of indole-2-carboxamides bearing photoactivatable functionalities as novel allosteric modulators for the cannabinoid CB1 receptor.Modulation of CB1 cannabinoid receptor by allosteric ligands: Pharmacology and therapeutic opportunities.Allosteric Modulators of the CB1 Cannabinoid Receptor: A Structural Update Review.Assessing Allosteric Modulation of CB1 at the Receptor and Cellular Levels.Allosteric modulators of cannabinoid receptor 1: developing compounds for improved specificity.Synthesis of benzofuranyl and indolyl methyl azides by tandem silver-catalyzed cyclization and azidation.
P2860
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P2860
Structure-activity relationship study of indole-2-carboxamides identifies a potent allosteric modulator for the cannabinoid receptor 1 (CB1).
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 07 October 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Structure-activity relationshi ...... cannabinoid receptor 1 (CB1).
@en
Structure-activity relationshi ...... for the cannabinoid receptor 1
@nl
type
label
Structure-activity relationshi ...... cannabinoid receptor 1 (CB1).
@en
Structure-activity relationshi ...... for the cannabinoid receptor 1
@nl
prefLabel
Structure-activity relationshi ...... cannabinoid receptor 1 (CB1).
@en
Structure-activity relationshi ...... for the cannabinoid receptor 1
@nl
P2093
P2860
P921
P356
P1476
Structure-activity relationshi ...... cannabinoid receptor 1 (CB1).
@en
P2093
Aparna Damaraju
Debra A Kendall
Kwang H Ahn
Srikanth Kolluru
Sushma Samala
Venkata K Pulipati
P2860
P304
P356
10.1021/JM4009828
P407
P577
2013-10-07T00:00:00Z