Cellular and systemic effects of anthrax lethal toxin and edema toxin.
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Gram-positive and gram-negative bacterial toxins in sepsis: a brief reviewAnthrax lethal toxin downregulates claudin-5 expression in human endothelial tight junctionsAnthrax infectionTumor Targeting and Drug Delivery by Anthrax ToxinDoes Bacillus anthracis Lethal Toxin Directly Depress Myocardial Function? A Review of Clinical Cases and Preclinical StudiesCrossing of the epithelial barriers by Bacillus anthracis: the Known and the UnknownBacillus anthracis factors for phagosomal escapeCytoskeleton as an emerging target of anthrax toxinsStudies in mice reveal a role for anthrax toxin receptors in matrix metalloproteinase function and extracellular matrix homeostasisThe potential contributions of lethal and edema toxins to the pathogenesis of anthrax associated shockAntidotes to anthrax lethal factor intoxication. Part 3: Evaluation of core structures and further modifications to the C2-side chainAlternative pre-approved and novel therapies for the treatment of anthraxRevisiting the Concept of Targeting Only Bacillus anthracis Toxins as a Treatment for AnthraxAn overview of anthrax infection including the recently identified form of disease in injection drug usersThe effects of anthrax lethal toxin on host barrier functionMonoclonal antibody therapies against anthraxAnthrax lethal toxin disrupts intestinal barrier function and causes systemic infections with enteric bacteriaAnthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasomeActivation of the Nlrp1b inflammasome by reduction of cytosolic ATPAnthrax lethal toxin activates the inflammasome in sensitive rat macrophagesDelayed toxicity associated with soluble anthrax toxin receptor decoy-Ig fusion protein treatmentIn trans complementation of lethal factor reveal roles in colonization and dissemination in a murine mouse model.Noninvasive imaging technologies reveal edema toxin as a key virulence factor in anthraxCirculating lethal toxin decreases the ability of neutrophils to respond to Bacillus anthracis.Susceptibility to anthrax lethal toxin-induced rat death is controlled by a single chromosome 10 locus that includes rNlrp1Anthrax lethal toxin suppresses murine cardiomyocyte contractile function and intracellular Ca2+ handling via a NADPH oxidase-dependent mechanismAuranofin protects against anthrax lethal toxin-induced activation of the Nlrp1b inflammasomeInflammasome sensor Nlrp1b-dependent resistance to anthrax is mediated by caspase-1, IL-1 signaling and neutrophil recruitment.Key tissue targets responsible for anthrax-toxin-induced lethality.Blockage of anthrax PA63 pore by a multicharged high-affinity toxin inhibitor.Anthrax lethal toxin induces acute diastolic dysfunction in rats through disruption of the phospholamban signaling networkAnthrax toxin-neutralizing antibody reconfigures the protective antigen heptamer into a supercomplex.Channel-forming bacterial toxins in biosensing and macromolecule deliveryMechanisms of NK cell-macrophage Bacillus anthracis crosstalk: a balance between stimulation by spores and differential disruption by toxins.Proteolytic processing of Nlrp1b is required for inflammasome activity.Antidotes to anthrax lethal factor intoxication. Part 1: Discovery of potent lethal factor inhibitors with in vivo efficacy.Confirmed Bacillus anthracis infection among persons who inject drugs, Scotland, 2009-2010.A chimeric protein that functions as both an anthrax dual-target antitoxin and a trivalent vaccine.Identification of peptide sequences as a measure of Anthrax vaccine stability during storage.Identification of exosite-targeting inhibitors of anthrax lethal factor by high-throughput screening
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P2860
Cellular and systemic effects of anthrax lethal toxin and edema toxin.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 26 July 2009
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vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Cellular and systemic effects of anthrax lethal toxin and edema toxin.
@en
Cellular and systemic effects of anthrax lethal toxin and edema toxin.
@nl
type
label
Cellular and systemic effects of anthrax lethal toxin and edema toxin.
@en
Cellular and systemic effects of anthrax lethal toxin and edema toxin.
@nl
prefLabel
Cellular and systemic effects of anthrax lethal toxin and edema toxin.
@en
Cellular and systemic effects of anthrax lethal toxin and edema toxin.
@nl
P2860
P1476
Cellular and systemic effects of anthrax lethal toxin and edema toxin.
@en
P2860
P304
P356
10.1016/J.MAM.2009.07.003
P577
2009-07-26T00:00:00Z