The role of inherited TPMT and COMT genetic variation in cisplatin-induced ototoxicity in children with cancer.
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Platinum-induced hearing loss after treatment for childhood cancerHuman OCT2 variant c.808G>T confers protection effect against cisplatin-induced ototoxicity.Pharmacogenomics in Pediatric Oncology: Review of Gene-Drug Associations for Clinical UsePharmacogenomics in Pediatric Patients: Towards Personalized MedicineInfluence of genetic variants in TPMT and COMT associated with cisplatin induced hearing loss in patients with cancer: two new cohorts and a meta-analysis reveal significant heterogeneity between cohorts.Pharmacogenomics--how close/far are we to practising individualized medicine for children?Common variants in ACYP2 influence susceptibility to cisplatin-induced hearing lossChemotherapy-induced peripheral neurotoxicity and ototoxicity: new paradigms for translational genomics.Pharmacogenetic variants in TPMT alter cellular responses to cisplatin in inner ear cell linesSOD2 genetic variant associated with treatment-related ototoxicity in cisplatin-treated pediatric medulloblastomaPharmacogenomics and adverse drug reactions in children.Biomarkers to assess the efficiency of treatment with platinum-based drugs: what can metallomics add?Pharmacogenetic Markers of Drug Efficacy and Toxicity.The role of germline variants in chemotherapy outcome in brain tumors: a systematic review of pharmacogenetic studies.TPMT, COMT and ACYP2 genetic variants in paediatric cancer patients with cisplatin-induced ototoxicity.Role of Preemptive Genotyping in Preventing Serious Adverse Drug Events in South Korean Patients.Promoter region variation in NFE2L2 influences susceptibility to ototoxicity in patients exposed to high cumulative doses of cisplatin.Genetic variation in Otos is associated with cisplatin-induced ototoxicity.Role of TPMT and COMT genetic variation in cisplatin-induced ototoxicity.Challenges in interpreting the evidence for genetic predictors of ototoxicity.Pharmacogenetics of drug-induced ototoxicity caused by aminoglycosides and cisplatin.Systematic review of pharmacogenomics and adverse drug reactions in paediatric oncology patients.Ototoxicity: A Challenge in Diagnosis and Treatment.Variants in WFS1 and Other Mendelian Deafness Genes Are Associated with Cisplatin-Associated Ototoxicity.Genetic markers of cisplatin-induced hearing loss in children.Response to "evaluation of pharmacogenetic markers to predict the risk of Cisplatin-induced ototoxicity".Evaluation of pharmacogenetic markers to predict the risk of Cisplatin-induced ototoxicity.'Toxgnostics': an unmet need in cancer medicine
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The role of inherited TPMT and COMT genetic variation in cisplatin-induced ototoxicity in children with cancer.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 11 June 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The role of inherited TPMT and ...... icity in children with cancer.
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The role of inherited TPMT and ...... icity in children with cancer.
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type
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The role of inherited TPMT and ...... icity in children with cancer.
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The role of inherited TPMT and ...... icity in children with cancer.
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The role of inherited TPMT and ...... icity in children with cancer.
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The role of inherited TPMT and ...... icity in children with cancer.
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The role of inherited TPMT and ...... icity in children with cancer.
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A Onar-Thomas
C F Stewart
E H Harstead
G W Robinson
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P304
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10.1038/CLPT.2013.121
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P577
2013-06-11T00:00:00Z