Angiotensin II-triggered p44/42 mitogen-activated protein kinase mediates sympathetic excitation in heart failure rats.
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Brain inflammation and hypertension: the chicken or the egg?Mitogen-activated protein kinases mediate upregulation of hypothalamic angiotensin II type 1 receptors in heart failure ratsEndogenous angiotensin II-induced p44/42 mitogen-activated protein kinase activation mediates sodium appetite but not thirst or neurohypophysial secretion in male rats.Centrally administered lipopolysaccharide elicits sympathetic excitation via NAD(P)H oxidase-dependent mitogen-activated protein kinase signaling.Central neuronal activation and pressor responses induced by circulating ANG II: role of the brain aldosterone-"ouabain" pathway.Central SDF-1/CXCL12 expression and its cardiovascular and sympathetic effects: the role of angiotensin II, TNF-α, and MAP kinase signaling.Proinflammatory cytokines upregulate sympathoexcitatory mechanisms in the subfornical organ of the rat.EP₃ receptors mediate PGE₂-induced hypothalamic paraventricular nucleus excitation and sympathetic activation.Peroxisome proliferator-activated receptor-γ regulates inflammation and renin-angiotensin system activity in the hypothalamic paraventricular nucleus and ameliorates peripheral manifestations of heart failure.Aldosterone-induced brain MAPK signaling and sympathetic excitation are angiotensin II type-1 receptor dependentCentral actions of the chemokine stromal cell-derived factor 1 contribute to neurohumoral excitation in heart failure ratsInhibition of Brain Mitogen-Activated Protein Kinase Signaling Reduces Central Endoplasmic Reticulum Stress and Inflammation and Sympathetic Nerve Activity in Heart Failure Rats.Early interference with p44/42 mitogen-activated protein kinase signaling in hypothalamic paraventricular nucleus attenuates angiotensin II-induced hypertension.ERK1/2 MAPK signaling in hypothalamic paraventricular nucleus contributes to sympathetic excitation in rats with heart failure after myocardial infarction.Angiotensin II upregulates hypothalamic AT1 receptor expression in rats via the mitogen-activated protein kinase pathway.Pharmacological treatment for heart failure: a view from the brain.Mineralocorticoid receptors, inflammation and sympathetic drive in a rat model of systolic heart failure.Increased Apoptosis in the Paraventricular Nucleus Mediated by AT1R/Ras/ERK1/2 Signaling Results in Sympathetic Hyperactivity and Renovascular Hypertension in Rats after Kidney Injury.PVN Blockade of p44/42 MAPK Pathway Attenuates Salt-induced Hypertension through Modulating Neurotransmitters and Attenuating Oxidative StressInvolvement of Cytokines in the Pathogenesis of Salt and Water Imbalance in Congestive Heart Failure.Endoplasmic reticulum stress increases brain MAPK signaling, inflammation and renin-angiotensin system activity and sympathetic nerve activity in heart failure.Central mechanisms of abnormal sympathoexcitation in chronic heart failure.PARP inhibition delays transition of hypertensive cardiopathy to heart failure in spontaneously hypertensive rats.Blood-borne Interleukin-1β Acts upon the Subfornical Organ to Upregulate the Sympathoexcitatory Milieu of the Hypothalamic Paraventricular Nucleus.Superoxide anions in the paraventricular nucleus mediate cardiac sympathetic afferent reflex in insulin resistance rats.Possible role of brain salt-inducible kinase 1 in responses to central sodium in Dahl rats.Cardiac sympathetic innervation and PGP9.5 expression by cardiomyocytes after myocardial infarction: effects of central MR blockade.Angiotensin II Type 1a Receptors in the Subfornical Organ Modulate Neuroinflammation in the Hypothalamic Paraventricular Nucleus in Heart Failure Rats.
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Angiotensin II-triggered p44/42 mitogen-activated protein kinase mediates sympathetic excitation in heart failure rats.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 23 June 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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Angiotensin II-triggered p44/4 ...... itation in heart failure rats.
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Angiotensin II-triggered p44/4 ...... itation in heart failure rats.
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Angiotensin II-triggered p44/4 ...... itation in heart failure rats.
@en
Angiotensin II-triggered p44/4 ...... itation in heart failure rats.
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Angiotensin II-triggered p44/4 ...... itation in heart failure rats.
@en
Angiotensin II-triggered p44/4 ...... itation in heart failure rats.
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Angiotensin II-triggered p44/4 ...... citation in heart failure rats
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Robert M Weiss
Zhi-Hua Zhang
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P304
P356
10.1161/HYPERTENSIONAHA.108.110445
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P577
2008-06-23T00:00:00Z