Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages.
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Functional Role of Milk Fat Globule-Epidermal Growth Factor VIII in Macrophage-Mediated Inflammatory Responses and Inflammatory/Autoimmune DiseasesThe Elusive Antifibrotic MacrophageAlways cleave up your mess: targeting collagen degradation to treat tissue fibrosisResolution of inflammation: an integrated viewRemodelling the extracellular matrix in development and diseaseMolecular classification of idiopathic pulmonary fibrosis: personalized medicine, genetics and biomarkersMilk fat globule epidermal growth factor VIII signaling in arterial wall remodelingMolecular mechanism and treatment of viral hepatitis-related liver fibrosis.αv integrins: key regulators of tissue fibrosisProtective and pathogenic functions of macrophage subsetsM2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway.Integrins αvβ5 and αvβ3 promote latent TGF-β1 activation by human cardiac fibroblast contractionCellular and molecular mechanisms in kidney fibrosis.Role of corneal collagen fibrils in corneal disorders and related pathological conditions.MFG-E8 regulates angiogenesis in cutaneous wound healingProgrammed cell clearance: molecular regulation of the elimination of apoptotic cell corpses and its role in the resolution of inflammation.Macrophages: master regulators of inflammation and fibrosis.MFGE8 does not influence chorio-retinal homeostasis or choroidal neovascularization in vivo.The transcription factor GLI1 modulates the inflammatory response during pancreatic tissue remodelingMilk fat globule-EGF factor VIII in sepsis and ischemia-reperfusion injuryNitrated fatty acids reverse pulmonary fibrosis by dedifferentiating myofibroblasts and promoting collagen uptake by alveolar macrophages.Fibrocytes are not an essential source of type I collagen during lung fibrosis.Mfge8 promotes obesity by mediating the uptake of dietary fats and serum fatty acids.Novel therapeutic approaches for pulmonary fibrosis.Milk fat globule-EGF factor 8 is a critical protein for healing of dextran sodium sulfate-induced acute colitis in mice.Integrating mechanisms of pulmonary fibrosisAccelerated receptor shedding inhibits kidney injury molecule-1 (KIM-1)-mediated efferocytosis.Pericyte-derived MFG-E8 regulates pathologic angiogenesisMatrix, mesenchyme, and mechanotransductionMannose receptor 2 attenuates renal fibrosisFibrosis is regulated by Th2 and Th17 responses and by dynamic interactions between fibroblasts and macrophagesMolecular Mechanisms Underlying the Regulation of the MFG-E8 Gene Promoter Activity in Physiological and Inflammatory Conditions.Fetal hematopoietic stem cells express MFG-E8 during mouse embryogenesis.MMP-10 Regulates Collagenolytic Activity of Alternatively Activated Resident MacrophagesMilk fat globule-epidermal growth factor-factor 8 attenuates neutrophil infiltration in acute lung injury via modulation of CXCR2.Deciphering Transcriptome and Complex Alternative Splicing Transcripts in Mammary Gland Tissues from Cows Naturally Infected with Staphylococcus aureus Mastitis.Loss of fibulin-4 disrupts collagen synthesis and maturation: implications for pathology resulting from EFEMP2 mutationsMilk fat globule--EGF factor VIII ameliorates liver injury after hepatic ischemia-reperfusion.Post-weaning increases in the milk-fat globule EGF-factor VIII on fat globules in mouse milk and in the uptake of the fat globules by HC11 mammary epithelial cells.Mfge8 suppresses airway hyperresponsiveness in asthma by regulating smooth muscle contraction.
P2860
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P2860
Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Mfge8 diminishes the severity ...... gen for uptake by macrophages.
@en
Mfge8 diminishes the severity ...... gen for uptake by macrophages.
@nl
type
label
Mfge8 diminishes the severity ...... gen for uptake by macrophages.
@en
Mfge8 diminishes the severity ...... gen for uptake by macrophages.
@nl
prefLabel
Mfge8 diminishes the severity ...... gen for uptake by macrophages.
@en
Mfge8 diminishes the severity ...... gen for uptake by macrophages.
@nl
P2093
P2860
P356
P1476
Mfge8 diminishes the severity ...... gen for uptake by macrophages.
@en
P2093
Andrew C Melton
Claire L Emson
Dean Sheppard
Dee Dee Xia
Greg Dehart
Kamran Atabai
Michael Lam
Nabil Azhar
Paul Wolters
P2860
P304
P356
10.1172/JCI40053
P407
P50
P577
2009-11-02T00:00:00Z