Post-translational modifications of Runx1 regulate its activity in the cell
about
Histone arginine methylation keeps RUNX1 target genes in an intermediate state.The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations.PRMT4 blocks myeloid differentiation by assembling a methyl-RUNX1-dependent repressor complex.SARS coronavirus 3b accessory protein modulates transcriptional activity of RUNX1b.The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation.Correlation of SRSF1 and PRMT1 expression with clinical status of pediatric acute lymphoblastic leukemiaLoss of RUNX1/AML1 arginine-methylation impairs peripheral T cell homeostasisAML1-ETO driven acute leukemia: insights into pathogenesis and potential therapeutic approaches.RUNX family: Regulation and diversification of roles through interacting proteins.RUNX1: A microRNA hub in normal and malignant hematopoiesis.Posttranslational modifications of RUNX1 as potential anticancer targets.RUNX1 represses the erythroid gene expression program during megakaryocytic differentiation.Tyrosyl phosphorylation toggles a Runx1 switch.Protein arginine methyltransferase 6 controls erythroid gene expression and differentiation of human CD34+ progenitor cells.Pin1-mediated prolyl isomerization of Runx1 affects PU.1 expression in pre-monocytes.is a RUNX1 target gene and promotes migration of NSCLC cells
P2860
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P2860
Post-translational modifications of Runx1 regulate its activity in the cell
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 21 April 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Post-translational modifications of Runx1 regulate its activity in the cell
@en
Post-translational modifications of Runx1 regulate its activity in the cell.
@nl
type
label
Post-translational modifications of Runx1 regulate its activity in the cell
@en
Post-translational modifications of Runx1 regulate its activity in the cell.
@nl
prefLabel
Post-translational modifications of Runx1 regulate its activity in the cell
@en
Post-translational modifications of Runx1 regulate its activity in the cell.
@nl
P2093
P2860
P1476
Post-translational modifications of Runx1 regulate its activity in the cell
@en
P2093
Gang Huang
Megan A Hatlen
Stephen D Nimer
Xinyang Zhao
P2860
P356
10.1016/J.BCMD.2009.03.005
P50
P577
2009-04-21T00:00:00Z