Alternative splicing and caspase-mediated cleavage generate antagonistic variants of the stress oncoprotein LEDGF/p75.
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Virological and cellular roles of the transcriptional coactivator LEDGF/p75Aberrant splicing and drug resistance in AMLCharacterization of LEDGF/p75 genetic variants and association with HIV-1 disease progression.SUMOylation of the lens epithelium-derived growth factor/p75 attenuates its transcriptional activity on the heat shock protein 27 promoter.Two membrane-associated regions within the Nodamura virus RNA-dependent RNA polymerase are critical for both mitochondrial localization and RNA replicationDifferential temporal and spatial progerin expression during closure of the ductus arteriosus in neonatesExpression of the stress response oncoprotein LEDGF/p75 in human cancer: a study of 21 tumor types.Role of the PWWP domain of lens epithelium-derived growth factor (LEDGF)/p75 cofactor in lentiviral integration targetingLEDGF/p75 Overexpression Attenuates Oxidative Stress-Induced Necrosis and Upregulates the Oxidoreductase ERP57/PDIA3/GRP58 in Prostate Cancer.Detection of autoantibodies to DSF70/LEDGFp75 in Mexican Hispanics using multiple complementary assay platformsIn search of second-generation HIV integrase inhibitors: targeting integration beyond strand transfer.Molecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis.A tutorial on protein ontology resources for proteomic studiesThe significance of autoantibodies to DFS70/LEDGFp75 in health and disease: integrating basic science with clinical understanding.Analysis of DFS70 pattern and impact on ANA screening using a novel HEp-2 ELITE/DFS70 knockout substrate.LEDGF (p75) promotes DNA-end resection and homologous recombination.The stress oncoprotein LEDGF/p75 interacts with the methyl CpG binding protein MeCP2 and influences its transcriptional activityPathway specific gene expression profiling reveals oxidative stress genes potentially regulated by transcription co-activator LEDGF/p75 in prostate cancer cells.High-resolution profiling of the LEDGF/p75 chromatin interaction in the ENCODE region.Docetaxel-induced prostate cancer cell death involves concomitant activation of caspase and lysosomal pathways and is attenuated by LEDGF/p75.Targeting the stress oncoprotein LEDGF/p75 to sensitize chemoresistant prostate cancer cells to taxanes.
P2860
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P2860
Alternative splicing and caspase-mediated cleavage generate antagonistic variants of the stress oncoprotein LEDGF/p75.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on August 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Alternative splicing and caspa ...... stress oncoprotein LEDGF/p75.
@en
Alternative splicing and caspa ...... stress oncoprotein LEDGF/p75.
@nl
type
label
Alternative splicing and caspa ...... stress oncoprotein LEDGF/p75.
@en
Alternative splicing and caspa ...... stress oncoprotein LEDGF/p75.
@nl
prefLabel
Alternative splicing and caspa ...... stress oncoprotein LEDGF/p75.
@en
Alternative splicing and caspa ...... stress oncoprotein LEDGF/p75.
@nl
P2093
P2860
P1476
Alternative splicing and caspa ...... stress oncoprotein LEDGF/p75.
@en
P2093
Carlos A Casiano
Fabio J Pacheco
Lai S Leoh
Maria Filippova
Melanie Mediavilla-Varela
Rik Gijsbers
Terry A Brown-Bryan
Thomas A Linkhart
Vidya Ganapathy
P2860
P304
P356
10.1158/1541-7786.MCR-08-0125
P577
2008-08-01T00:00:00Z