Structures of beta-amyloid peptide 1-40, 1-42, and 1-55-the 672-726 fragment of APP-in a membrane environment with implications for interactions with gamma-secretase
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Dimeric structure of transmembrane domain of amyloid precursor protein in micellar environmentMolecular dynamics simulations of biological membranes and membrane proteins using enhanced conformational sampling algorithmsMembrane sculpting by F-BAR domains studied by molecular dynamics simulationsThe Amyloid Precursor Protein Has a Flexible Transmembrane Domain and Binds CholesterolEffects of surface interactions on peptide aggregate morphology.Non-esterified fatty acids generate distinct low-molecular weight amyloid-β (Aβ42) oligomers along pathway different from fibril formationAmyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies.Evidence from solid-state NMR for nonhelical conformations in the transmembrane domain of the amyloid precursor protein.Impact of membrane lipid composition on the structure and stability of the transmembrane domain of amyloid precursor protein.Transmembrane fragment structures of amyloid precursor protein depend on membrane surface curvature.Perturbations of the straight transmembrane α-helical structure of the amyloid precursor protein affect its processing by γ-secretase.Biochemistry of amyloid β-protein and amyloid deposits in Alzheimer disease.Interactions between proteins and carbon-based nanoparticles: exploring the origin of nanotoxicity at the molecular level.The role of molecular simulations in the development of inhibitors of amyloid β-peptide aggregation for the treatment of Alzheimer's diseaseImpact of bilayer lipid composition on the structure and topology of the transmembrane amyloid precursor C99 proteinAlzheimer Aβ peptide interactions with lipid membranes: fibrils, oligomers and polymorphic amyloid channels.Stability of transmembrane amyloid β-peptide and membrane integrity tested by molecular modeling of site-specific Aβ42 mutations.Designed fluorescent probes reveal interactions between amyloid-beta(1-40) peptides and GM1 gangliosides in micelles and lipid vesicles.Competition between homodimerization and cholesterol binding to the C99 domain of the amyloid precursor protein.AβP1-42 incorporation and channel formation in planar lipid membranes: the role of cholesterol and its oxidation products.Kinetic pathways to peptide aggregation on surfaces: the effects of β-sheet propensity and surface attraction.Investigation of the interaction of amyloid β peptide (11-42) oligomers with a 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) membrane using molecular dynamics simulation.Similarity search combined with docking and molecular dynamics for novel hAChE inhibitor scaffolds.Interference of α-Synuclein Uptake by Monomeric β-Amyloid1-40 and Potential Core Acting Site of the Interference.Toward high permeability, selectivity and controllability of water desalination with FePc nanopores.
P2860
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P2860
Structures of beta-amyloid peptide 1-40, 1-42, and 1-55-the 672-726 fragment of APP-in a membrane environment with implications for interactions with gamma-secretase
description
article científic
@ca
article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Structures of beta-amyloid pep ...... eractions with gamma-secretase
@en
Structures of beta-amyloid pep ...... ractions with gamma-secretase.
@nl
type
label
Structures of beta-amyloid pep ...... eractions with gamma-secretase
@en
Structures of beta-amyloid pep ...... ractions with gamma-secretase.
@nl
prefLabel
Structures of beta-amyloid pep ...... eractions with gamma-secretase
@en
Structures of beta-amyloid pep ...... ractions with gamma-secretase.
@nl
P2093
P2860
P356
P1476
Structures of beta-amyloid pep ...... eractions with gamma-secretase
@en
P2093
D Thirumalai
John E Straub
Naoyuki Miyashita
P2860
P304
17843-17852
P356
10.1021/JA905457D
P407
P577
2009-12-01T00:00:00Z