Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
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Undercover: gene control by metabolites and metabolic enzymesEpigenetic determinants of metastasisRapamycin (mTORC1 inhibitor) reduces the production of lactate and 2-hydroxyglutarate oncometabolites in IDH1 mutant fibrosarcoma cellsMitochondrial Deficiencies in the Predisposition to ParagangliomaMetabolic reprogramming and epithelial-to-mesenchymal transition in cancer.Deep-proteome mapping of WM-266-4 human metastatic melanoma cells: From oncogenic addiction to druggable targetsChemical signaling between gut microbiota and host chromatin: What is your gut really saying?Deletion of Type 3 Adenylyl Cyclase Perturbs the Postnatal Maturation of Olfactory Sensory Neurons and Olfactory Cilium Ultrastructure in Mice.Deciphering Epithelial-Mesenchymal Transition Regulatory Networks in Cancer through Computational ApproachesUsing chemical biology to assess and modulate mitochondria: progress and challenges.The cancer epigenome: Concepts, challenges, and therapeutic opportunities.Marked for death: targeting epigenetic changes in cancer.DNA demethylation pathways: Additional players and regulators.Cancer Metabolism: Fueling More than Just GrowthThe α-ketoglutarate dehydrogenase complex in cancer metabolic plasticity.Understanding the Intersections between Metabolism and Cancer Biology.Targeting the Metabolic Reprogramming That Controls Epithelial-to-Mesenchymal Transition in Aggressive Tumors.Mitochondrial metabolites: undercover signalling molecules.The Chaperone TRAP1 As a Modulator of the Mitochondrial Adaptations in Cancer Cells.The Close Interconnection between Mitochondrial Dynamics and Mitophagy in Cancer.Krebs cycle rewired for macrophage and dendritic cell effector functions.Exploiting tumour addiction with a serine and glycine-free diet.A new holistic 3D non-invasive analysis of cellular distribution and motility on fibroin-alginate microcarriers using light sheet fluorescent microscopy.Fumarate drives EMT in renal cancer.The mitochondrial respiratory chain is essential for haematopoietic stem cell function.Fumarate Hydratase Loss Causes Combined Respiratory Chain Defects.Pregnancy Reprograms Large-Conductance Ca2+-Activated K+ Channel in Uterine Arteries: Roles of Ten-Eleven Translocation Methylcytosine Dioxygenase 1-Mediated Active Demethylation.Metabolism in cancer metastasis: bioenergetics, biosynthesis, and beyond.Molecular Pathways: Metabolic Control of Histone Methylation and Gene Expression in Cancer.A20 enhances the radiosensitivity of hepatocellular carcinoma cells to 60Co-γ ionizing radiation.An integrated computational and experimental study uncovers FUT9 as a metabolic driver of colorectal cancer.The chemistries and consequences of DNA and RNA methylation and demethylation.Characterization of epithelial-mesenchymal transition intermediate/hybrid phenotypes associated to resistance to EGFR inhibitors in non-small cell lung cancer cell lines.Metabolic coupling and the Reverse Warburg Effect in cancer: Implications for novel biomarker and anticancer agent development.Post-translational regulation of metabolism in fumarate hydratase deficient cancer cells.ADHFE1 is a breast cancer oncogene and induces metabolic reprogramming.The impact of cellular metabolism on chromatin dynamics and epigenetics.Hereditary leiomyomatosis and renal cell cancer syndrome: A novel mutation in the FH gene.Metabolism and Transcription in Cancer: Merging Two Classic Tales.The TET enzymes.
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Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 31 August 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
@en
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition.
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type
label
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
@en
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition.
@nl
prefLabel
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
@en
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition.
@nl
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P1476
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
@en
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Alizee Vercauteren Drubbel
Ana Sofia Henriques da Costa
Anne Warren
Eamonn Richard Maher
Edoardo Gaude
Haiyang Yun
Marco Sciacovelli
Pedro Cutillas
Sandra Riekje Abbo
Sarah Foster
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P2888
P304
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10.1038/NATURE19353
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P577
2016-08-31T00:00:00Z