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ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaksImaging Transcription: Past, Present, and FutureRegulation of Spatiotemporal Patterns by Biological Variability: General Principles and Applications to Dictyostelium discoideumTranscription goes digitalQuantitative imaging of mammalian transcriptional dynamics: from single cells to whole embryosThe intimate genome… in three dimensionsGenome-wide modeling of transcription preinitiation complex disassembly mechanisms using ChIP-chip dataProtein complex formation: computational clarification of the sequential versus probabilistic recruitment puzzleA transgenic mouse for in vivo detection of endogenous labeled mRNA.Quantifying the transcriptional output of single alleles in single living mammalian cells.Robustness of DNA repair through collective rate control.Reconciling the concurrent fast and slow cycling of proteins on gene promoters.Single-molecule tracking in live cells reveals distinct target-search strategies of transcription factors in the nucleus.Altered dynamics of intestinal cell maturation in Apc1638N/+ mice.An on-bead tailing/ligation approach for sequencing resin-bound RNA libraries.Mammalian genes are transcribed with widely different bursting kinetics.RNA processing and exportLooping back to leap forward: transcription enters a new eraImaging RNA Polymerase II transcription sites in living cellsA perspective of the dynamic structure of the nucleus explored at the single-molecule levelDynamics of the full length and mutated heat shock factor 1 in human cellsMechanisms of specificity in neuronal activity-regulated gene transcriptionDetection of nascent RNA, single-copy DNA and protein localization by immunoFISH in mouse germ cells and preimplantation embryos.Modern fluorescent proteins and imaging technologies to study gene expression, nuclear localization, and dynamics.Nuclear physics: quantitative single-cell approaches to nuclear organization and gene expressionReal-time observation of transcription initiation and elongation on an endogenous yeast geneAro: a machine learning approach to identifying single molecules and estimating classification error in fluorescence microscopy imagesSingle-molecule insights into mRNA dynamics in neurons.Dynamic mechanism for the transcription apparatus orchestrating reliable responses to activators.Single cell genomics of the brain: focus on neuronal diversity and neuropsychiatric diseases.Cellular response to heat shock studied by multiconfocal fluorescence correlation spectroscopy.What do expression dynamics tell us about the mechanism of transcription?Direct observation of frequency modulated transcription in single cells using light activation.Eukaryotic transcriptional dynamics: from single molecules to cell populations.Super-resolution imaging of fluorescently labeled, endogenous RNA Polymerase II in living cells with CRISPR/Cas9-mediated gene editingA single molecule view of gene expression.Kinetics of promoter Pol II on Hsp70 reveal stable pausing and key insights into its regulation.Kinetics of transcription initiation directed by multiple cis-regulatory elements on the glnAp2 promoter.An architectural genetic and epigenetic perspective.Assembly of the transcription machinery: ordered and stable, random and dynamic, or both?
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Imaging transcription in living cells.
@en
Imaging transcription in living cells.
@nl
type
label
Imaging transcription in living cells.
@en
Imaging transcription in living cells.
@nl
prefLabel
Imaging transcription in living cells.
@en
Imaging transcription in living cells.
@nl
P2093
P2860
P50
P1476
Imaging transcription in living cells
@en
P2093
Benjamin Guglielmi
Lana Bosanac
Robert H Singer
Robert Tjian
P2860
P304
P356
10.1146/ANNUREV.BIOPHYS.050708.133728
P50
P577
2009-01-01T00:00:00Z