Stabilization of XIAP mRNA through the RNA binding protein HuR regulated by cellular polyamines.
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RNA-binding proteins and microRNAs in gastrointestinal epithelial homeostasis and diseasesRegulation of AU-Rich Element RNA Binding Proteins by Phosphorylation and the Prolyl Isomerase Pin1Post-transcriptional regulation of Wnt co-receptor LRP6 and RNA-binding protein HuR by miR-29b in intestinal epithelial cellsInduced ATF-2 represses CDK4 transcription through dimerization with JunD inhibiting intestinal epithelial cell growth after polyamine depletionPolyamines regulate the stability of JunD mRNA by modulating the competitive binding of its 3' untranslated region to HuR and AUF1Chk2-dependent HuR phosphorylation regulates occludin mRNA translation and epithelial barrier functionVariations in the protein level of Omi/HtrA2 in the heart of aged rats may contribute to the increased susceptibility of cardiomyocytes to ischemia/reperfusion injury and cell death : Omi/HtrA2 and aged heart injuryAttenuation of the ELAV1-like protein HuR sensitizes adenocarcinoma cells to the intrinsic apoptotic pathway by increasing the translation of caspase-2L.Arylazopyrazole AAP1742 inhibits CDKs and induces apoptosis in multiple myeloma cells via Mcl-1 downregulation.The fungal natural product azaphilone-9 binds to HuR and inhibits HuR-RNA interaction in vitro.Jnk2 deletion disrupts intestinal mucosal homeostasis and maturation by differentially modulating RNA-binding proteins HuR and CUGBP1.Sindbis virus usurps the cellular HuR protein to stabilize its transcripts and promote productive infections in mammalian and mosquito cells.ADAM15 exerts an antiapoptotic effect on osteoarthritic chondrocytes via up-regulation of the X-linked inhibitor of apoptosis.Polyamines and Gut Mucosal Homeostasis.miR-503 represses CUG-binding protein 1 translation by recruiting CUGBP1 mRNA to processing bodies.RNA-binding protein HuR regulates RGS4 mRNA stability in rabbit colonic smooth muscle cells.RNA-binding protein HuR promotes growth of small intestinal mucosa by activating the Wnt signaling pathway.Post-transcriptional regulation of MEK-1 by polyamines through the RNA-binding protein HuR modulating intestinal epithelial apoptosis.Modulation by miR-29b of intestinal epithelium homoeostasis through the repression of menin translation.Regulation of cyclin-dependent kinase 4 translation through CUG-binding protein 1 and microRNA-222 by polyaminesIdentification and validation of novel small molecule disruptors of HuR-mRNA interaction.Competition between RNA-binding proteins CELF1 and HuR modulates MYC translation and intestinal epithelium renewal.JunD enhances miR-29b levels transcriptionally and posttranscriptionally to inhibit proliferation of intestinal epithelial cells.Polyamines regulate intestinal epithelial restitution through TRPC1-mediated Ca²+ signaling by differentially modulating STIM1 and STIM2.RNA-binding protein HuR mediates cytoprotection through stimulation of XIAP translation.Competitive binding of CUGBP1 and HuR to occludin mRNA controls its translation and modulates epithelial barrier function.Posttranscriptional regulation of 14-3-3ζ by RNA-binding protein HuR modulating intestinal epithelial restitution after wounding.miR-195 competes with HuR to modulate stim1 mRNA stability and regulate cell migrationInflammation: cytokines and RNA-based regulation.Inhibition of Smurf2 translation by miR-322/503 modulates TGF-β/Smad2 signaling and intestinal epithelial homeostasis.Posttranscriptional Regulation of Intestinal Epithelial Tight Junction Barrier by RNA-binding Proteins and microRNAsCold-inducible RNA-binding protein (CIRP) regulates target mRNA stabilization in the mouse testis.Transcriptional regulation of importin-α1 by JunD modulates subcellular localization of RNA-binding protein HuR in intestinal epithelial cells.Anti-apoptotic protein BRE/BRCC45 attenuates apoptosis through maintaining the expression of caspase inhibitor XIAP in mouse Lewis lung carcinoma D122 cells.HuR-targeted small molecule inhibitor exhibits cytotoxicity towards human lung cancer cells.HuR Enhances Early Restitution of the Intestinal Epithelium by Increasing Cdc42 Translation.Expression profiling and biochemical analysis suggest stress response as a potential mechanism inhibiting proliferation of polyamine-depleted cellsCooperative Repression of Insulin-Like Growth Factor Type 2 Receptor Translation by MicroRNA 195 and RNA-Binding Protein CUGBP1.
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P2860
Stabilization of XIAP mRNA through the RNA binding protein HuR regulated by cellular polyamines.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on December 2009
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vedecký článok
@sk
vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Stabilization of XIAP mRNA thr ...... ulated by cellular polyamines.
@en
Stabilization of XIAP mRNA thr ...... ulated by cellular polyamines.
@nl
type
label
Stabilization of XIAP mRNA thr ...... ulated by cellular polyamines.
@en
Stabilization of XIAP mRNA thr ...... ulated by cellular polyamines.
@nl
prefLabel
Stabilization of XIAP mRNA thr ...... ulated by cellular polyamines.
@en
Stabilization of XIAP mRNA thr ...... ulated by cellular polyamines.
@nl
P2093
P2860
P356
P1476
Stabilization of XIAP mRNA thr ...... ulated by cellular polyamines.
@en
P2093
Jaladanki N Rao
Jian-Ying Wang
Peng-Yuan Wang
Tongtong Zou
Xian Zhang
Yu-Hong Cui
P2860
P304
P356
10.1093/NAR/GKP755
P407
P577
2009-12-01T00:00:00Z