RNA-binding protein HuR mediates cytoprotection through stimulation of XIAP translation.
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RNA-binding protein HuR autoregulates its expression by promoting alternative polyadenylation site usageHallmarks of cancer and AU-rich elementsFunctional interplay between RNA-binding protein HuR and microRNAsThe RNA-binding protein Gemin5 binds directly to the ribosome and regulates global translationVersatility of RNA-Binding Proteins in CancerTracking fluctuation hotspots on the yeast ribosome through the elongation cycleKrüppel -like factor 8 is a stress-responsive transcription factor that regulates expression of HuR.HuR controls mitochondrial morphology through the regulation of BclxL translation.Hu antigen R (HuR) is a positive regulator of the RNA-binding proteins TDP-43 and FUS/TLS: implications for amyotrophic lateral sclerosis.The RNA-binding protein HuR promotes glioma growth and treatment resistance.RNA-binding protein insulin-like growth factor mRNA-binding protein 3 (IMP-3) promotes cell survival via insulin-like growth factor II signaling after ionizing radiation.Identification and validation of novel small molecule disruptors of HuR-mRNA interaction.The oncogenic RNA-binding protein Musashi1 is regulated by HuR via mRNA translation and stability in glioblastoma cellsSex hormone-dependent attenuation of EAE in a transgenic mouse with astrocytic expression of the RNA regulator HuR.Tumor suppressor PDCD4 represses internal ribosome entry site-mediated translation of antiapoptotic proteins and is regulated by S6 kinase 2.HuR function in disease.HuR's post-transcriptional regulation of Death Receptor 5 in pancreatic cancer cells.ERK8 is a novel HuR kinase that regulates tumour suppressor PDCD4 through a miR-21 dependent mechanismSmall molecule inhibitors of IRES-mediated translation.RNA-binding proteins impacting on internal initiation of translation.Role of Eukaryotic Initiation Factors during Cellular Stress and Cancer ProgressionEstablishment of chronic hepatitis C virus infection: translational evasion of oxidative defenceHu Antigen R (HuR) multimerization contributes to glioma disease progression.HuR promotes the molecular signature and phenotype of activated microglia: Implications for amyotrophic lateral sclerosis and other neurodegenerative diseases.Post-transcriptional regulation of cytokine and growth factor signaling in cancer.Anti-apoptotic protein BRE/BRCC45 attenuates apoptosis through maintaining the expression of caspase inhibitor XIAP in mouse Lewis lung carcinoma D122 cells.Human antigen R-mediated mRNA stabilization is required for ultraviolet B-induced autoinduction of amphiregulin in keratinocytes.Identification of novel non-canonical RNA-binding sites in Gemin5 involved in internal initiation of translation.Cellular mRNA recruits the ribosome via eIF3-PABP bridge to initiate internal translation.HuR-targeted small molecule inhibitor exhibits cytotoxicity towards human lung cancer cells.Phosphorylation of XIAP by CDK1-cyclin-B1 controls mitotic cell death.hnRNPs and ELAVL1 cooperate with uORFs to inhibit protein translation.Activation of HuR downstream of p38 MAPK promotes cardiomyocyte hypertrophy.RNA Binding Protein as an Emerging Therapeutic Target for Cancer Prevention and Treatment.Transgenic expression of HuR increases vasogenic edema and impedes functional recovery in rodent ischemic stroke.Emerging role of HuR in inflammatory response in kidney diseases.Emerging roles of hnRNPA1 in modulating malignant transformation.RNA Binding Protein Human Antigen R Is Translocated in Astrocytes following Spinal Cord Injury and Promotes the Inflammatory Response.
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RNA-binding protein HuR mediates cytoprotection through stimulation of XIAP translation.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
RNA-binding protein HuR mediates cytoprotection through stimulation of XIAP translation.
@ast
RNA-binding protein HuR mediates cytoprotection through stimulation of XIAP translation.
@en
type
label
RNA-binding protein HuR mediates cytoprotection through stimulation of XIAP translation.
@ast
RNA-binding protein HuR mediates cytoprotection through stimulation of XIAP translation.
@en
prefLabel
RNA-binding protein HuR mediates cytoprotection through stimulation of XIAP translation.
@ast
RNA-binding protein HuR mediates cytoprotection through stimulation of XIAP translation.
@en
P2093
P2860
P356
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P1476
RNA-binding protein HuR mediates cytoprotection through stimulation of XIAP translation
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2010.527
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P577
2010-11-22T00:00:00Z