Prediction of rodent nongenotoxic carcinogenesis: evaluation of biochemical and tissue changes in rodents following exposure to nine nongenotoxic NTP carcinogens.
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Using nuclear receptor activity to stratify hepatocarcinogensData mining in the U.S. National Toxicology Program (NTP) database reveals a potential bias regarding liver tumors in rodents irrespective of the test agent.A data-based assessment of alternative strategies for identification of potential human cancer hazards.An integrated functional genomic study of acute phenobarbital exposure in the ratNew short term prediction method for chemical carcinogenicity by hepatic transcript profiling following 28-day toxicity tests in rats.Chemically induced renal tubule tumors in the laboratory rat and mouse: review of the NCI/NTP database and categorization of renal carcinogens based on mechanistic information.Phthalates Are Metabolised by Primary Thyroid Cell Cultures but Have Limited Influence on Selected Thyroid Cell Functions In VitroEditor's Highlight: Negative Predictors of Carcinogenicity for Environmental Chemicals.Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor.A metabolomics investigation of non-genotoxic carcinogenicity in the rat.Xenobiotic CAR activators induce Dlk1-Dio3 locus non-coding RNA expression in mouse liver.Metabolic response to low-level toxicant exposure in a novel renal tubule epithelial cell system.Hepatic effects of repeated oral administration of diclofenac to hepatic cytochrome P450 reductase null (HRN™) and wild-type mice.Comparative time course profiles of phthalate stereoisomers in mice.Development and evaluation of a genomic signature for the prediction and mechanistic assessment of nongenotoxic hepatocarcinogens in the rat.Prediction of rodent carcinogenesis: an evaluation of prechronic liver lesions as forecasters of liver tumors in NTP carcinogenicity studies.Ectonucleoside triphosphate diphosphohydrolase type 5 (Entpd5)-deficient mice develop progressive hepatopathy, hepatocellular tumors, and spermatogenic arrest.An integrative test strategy for cancer hazard identification.Associations between urinary concentrations of 2,5-dichlorophenol and metabolic syndrome among non-diabetic adults.Urinary concentrations of 2,5-dichlorophenol and diabetes in US adults.Renal tumors in male rats following long-term administration of bazedoxifene, a tissue-selective estrogen receptor modulator.Revisiting alternative approaches to the assessment of carcinogenic risk.Biomarkers of carcinogenicity and their roles in drug discovery and development.
P2860
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P2860
Prediction of rodent nongenotoxic carcinogenesis: evaluation of biochemical and tissue changes in rodents following exposure to nine nongenotoxic NTP carcinogens.
description
2002 nî lūn-bûn
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2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2002 թվականի ապրիլին հրատարակված գիտական հոդված
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2002年の論文
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2002年学术文章
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2002年学术文章
@zh-cn
2002年学术文章
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2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
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name
Prediction of rodent nongenoto ...... e nongenotoxic NTP carcinogens
@nl
Prediction of rodent nongenoto ...... nongenotoxic NTP carcinogens.
@ast
Prediction of rodent nongenoto ...... nongenotoxic NTP carcinogens.
@en
type
label
Prediction of rodent nongenoto ...... e nongenotoxic NTP carcinogens
@nl
Prediction of rodent nongenoto ...... nongenotoxic NTP carcinogens.
@ast
Prediction of rodent nongenoto ...... nongenotoxic NTP carcinogens.
@en
prefLabel
Prediction of rodent nongenoto ...... e nongenotoxic NTP carcinogens
@nl
Prediction of rodent nongenoto ...... nongenotoxic NTP carcinogens.
@ast
Prediction of rodent nongenoto ...... nongenotoxic NTP carcinogens.
@en
P2093
P2860
P356
P1476
Prediction of rodent nongenoto ...... nongenotoxic NTP carcinogens.
@en
P2093
Anthony R Soames
Clifford R Elcombe
Ian Kimber
Jenny Odum
John Ashby
John R Foster
Susan Hasmall
Susan Stone
P2860
P304
P356
10.1289/EHP.02110363
P407
P577
2002-04-01T00:00:00Z