Construction of a "mutagenesis cartridge" for poliovirus genome-linked viral protein: isolation and characterization of viable and nonviable mutants
about
NMR structure of the viral peptide linked to the genome (VPg) of poliovirusPoliovirus type 1/type 3 antigenic hybrid virus constructed in vitro elicits type 1 and type 3 neutralizing antibodies in rabbits and monkeys.Engineered picornavirus VPg-RNA substrates: analysis of a tyrosyl-RNA phosphodiesterase activity.Biochemical and genetic studies of the VPg uridylylation reaction catalyzed by the RNA polymerase of poliovirusProtein-primed RNA synthesis by purified poliovirus RNA polymerase.Poliovirus CRE-dependent VPg uridylylation is required for positive-strand RNA synthesis but not for negative-strand RNA synthesisGenetic variation of the poliovirus genome with two VPg coding units.Reversible dissociation of the poliovirus replication complex: functions and interactions of its components in viral RNA synthesisDivergent Requirement for a DNA Repair Enzyme during Enterovirus Infections.Coupled translation and replication of poliovirus RNA in vitro: synthesis of functional 3D polymerase and infectious virusRole of a viral membrane polypeptide in strand-specific initiation of poliovirus RNA synthesis.Role of 3'-end sequences in infectivity of poliovirus transcripts made in vitro.Conditional poliovirus mutants made by random deletion mutagenesis of infectious cDNA.Characterization of poliovirus clones containing lethal and nonlethal mutations in the genome-linked protein VPg.Mutational analysis of the genome-linked protein VPg of poliovirus.Complete protein linkage map of poliovirus P3 proteins: interaction of polymerase 3Dpol with VPg and with genetic variants of 3AB.Viability of poliovirus/rhinovirus VPg chimeric viruses and identification of an amino acid residue in the VPg gene critical for viral RNA replicationEfficient analysis of nonviable poliovirus capsid mutants.A tyrosine residue in the small nuclear inclusion protein of tobacco vein mottling virus links the VPg to the viral RNA.Sequence specificity for uridylylation of the viral peptide linked to the genome (VPg) of enteroviruses.Poliovirus host range is determined by a short amino acid sequence in neutralization antigenic site I.
P2860
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P2860
Construction of a "mutagenesis cartridge" for poliovirus genome-linked viral protein: isolation and characterization of viable and nonviable mutants
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 1988
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Construction of a "mutagenesis ...... f viable and nonviable mutants
@en
Construction of a "mutagenesis ...... viable and nonviable mutants.
@nl
type
label
Construction of a "mutagenesis ...... f viable and nonviable mutants
@en
Construction of a "mutagenesis ...... viable and nonviable mutants.
@nl
prefLabel
Construction of a "mutagenesis ...... f viable and nonviable mutants
@en
Construction of a "mutagenesis ...... viable and nonviable mutants.
@nl
P2093
P2860
P356
P1476
Construction of a "mutagenesis ...... f viable and nonviable mutants
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P2093
P2860
P304
P356
10.1073/PNAS.85.2.519
P407
P577
1988-01-01T00:00:00Z