Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling - Wikidata - awgldk - TriplyDB

Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling

Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling

http://www.wikidata.org/entity/Q37487211

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Tumor suppressor protein VHL inhibits Hedgehog-Gli activation through suppression of Gli1 nuclear localization Activation of the hedgehog pathway in advanced prostate cancer Osteopontin-A Master Regulator of Epithelial-Mesenchymal Transition Targeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI Inhibitors Targeting self-renewal pathways in cancer stem cells: clinical implications for cancer therapy Hedgehog Cholesterolysis: Specialized Gatekeeper to Oncogenic Signaling Clinical Implications of Hedgehog Pathway Signaling in Prostate Cancer The Role of Hedgehog Signaling in Tumor Induced Bone Disease Cooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapy Context-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapy A microRNA code for prostate cancer metastasis.Inhibition of Hedgehog signaling antagonizes serous ovarian cancer growth in a primary xenograft model Hedgehog pathway activity in the LADY prostate tumor model Hedgehog signaling and the Gli code in stem cells, cancer, and metastases Hedgehog Proteins Consume Steroidal CYP17A1 Antagonists: Potential Therapeutic Significance in Advanced Prostate Cancer Norcantharidin, derivative of cantharidin, for cancer stem cells Chemoresistance in prostate cancer cells is regulated by miRNAs and Hedgehog pathway Self-renewal of acute lymphocytic leukemia cells is limited by the Hedgehog pathway inhibitors cyclopamine and IPI-926 Significance of sonic hedgehog signaling after massive hepatectomy in a rat.Targeting GLI1 expression in human inflammatory breast cancer cells enhances apoptosis and attenuates migration.Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancer.Common activation of canonical Wnt signaling in pancreatic adenocarcinoma.Gli-1 siRNA induced apoptosis in Huh7 cells.Recent patents for Hedgehog pathway inhibitors for the treatment of malignancy.Structure-activity relationships and cancer-cell selective toxicity of novel inhibitors of glioma-associated oncogene homologue 1 (Gli1) mediated transcription.Hedgehog pathway responsiveness correlates with the presence of primary cilia on prostate stromal cells GLI1 is a central mediator of EWS/FLI1 signaling in Ewing tumors.Cytotoxic effects induced by docetaxel, gefitinib, and cyclopamine on side population and nonside population cell fractions from human invasive prostate cancer cells.Genetic variations regulate alternative splicing in the 5' untranslated regions of the mouse glioma-associated oncogene 1, Gli1.The Sex-determining region Y-box 4 and homeobox C6 transcriptional networks in prostate cancer progression: crosstalk with the Wnt, Notch, and PI3K pathways Effects of inhibition of hedgehog signaling on cell growth and migration of uveal melanoma cells.cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells.Oestrogen receptor-alpha contributes to the regulation of the hedgehog signalling pathway in ERalpha-positive gastric cancer New hedgehog/GLI-signaling inhibitors from Adenium obesum.Hedgehog/Gli supports androgen signaling in androgen deprived and androgen independent prostate cancer cells.Cancer stem cells: a novel paradigm for cancer prevention and treatment.Beta1 integrins mediate cell proliferation in three-dimensional cultures by regulating expression of the sonic hedgehog effector protein, GLI1.GLI1 confers profound phenotypic changes upon LNCaP prostate cancer cells that include the acquisition of a hormone independent state Targeting Hedgehog--a cancer stem cell pathway Gene expression profiling of the hedgehog signaling pathway in human meningiomas.

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Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling

http://www.wikidata.org/entity/Q37487211

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 16 August 2004

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Inhibition of prostate cancer ...... SONIC HEDGEHOG-GLI1 signaling

@en

Inhibition of prostate cancer ...... SONIC HEDGEHOG-GLI1 signaling.

@nl

type

label

Inhibition of prostate cancer ...... SONIC HEDGEHOG-GLI1 signaling

@en

Inhibition of prostate cancer ...... SONIC HEDGEHOG-GLI1 signaling.

@nl

prefLabel

Inhibition of prostate cancer ...... SONIC HEDGEHOG-GLI1 signaling

@en

Inhibition of prostate cancer ...... SONIC HEDGEHOG-GLI1 signaling.

@nl

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PNAS.0404956101

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Proceedings of the National Academy of Sciences of the United States of America

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Inhibition of prostate cancer ...... SONIC HEDGEHOG-GLI1 signaling

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Amy M DeGueme

http://www.w3.org/2001/XMLSchema#string

Ana Maria Hernández

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Andrea Barrett

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Andrea J Kahler

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Ariel Ruiz i Altaba

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Milton W Datta

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Pilar Sanchez

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Sumana Datta

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P2860

Human GLI2 and GLI1 are part of a positive feedback mechanism in Basal Cell Carcinoma

Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

The magnitude of hedgehog signaling activity defines skin tumor phenotype

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

Stem cells, cancer, and cancer stem cells

Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation

Identification of PATCHED mutations in medulloblastomas by direct sequencing

Patched and smoothened mRNA expression in human astrocytic tumors inversely correlates with histological malignancy

Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

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10.1073/PNAS.0404956101

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