Mini-chromosomes derived from the human Y chromosome by telomere directed chromosome breakage.
about
A new generation of human artificial chromosomes for functional genomics and gene therapyRefined human artificial chromosome vectors for gene therapy and animal transgenesisThe role of DNA sequence in centromere formationA pathway from chromosome transfer to engineering resulting in human and mouse artificial chromosomes for a variety of applications to bio-medical challengesTelomere-mediated chromosomal truncation in maizeConstruction and behavior of engineered minichromosomes in maizeFormation of de novo centromeres and construction of first-generation human artificial microchromosomesNovel method to load multiple genes onto a mammalian artificial chromosomeCloning of human centromeres by transformation-associated recombination in yeast and generation of functional human artificial chromosomes.An analphoid marker chromosome inv dup(15)(q26.1qter), detected during prenatal diagnosis and characterized via chromosome microdissection.Genetic modification of mammalian genome at chromosome level.Bi-HAC vector system toward gene and cell therapyMolecular structure of a functional Drosophila centromere.Strategies for engineering human chromosomes with therapeutic potential.Meiotic transmission rates correlate with physical features of rearranged centromeres in maize.De novo assembly of potential linear artificial chromosome constructs capped with expansive telomeric repeatsEfficient male and female germline transmission of a human chromosomal vector in mice.An artificially constructed de novo human chromosome behaves almost identically to its natural counterpart during metaphase and anaphase in living cellsHuman artificial chromosomes for gene delivery and the development of animal modelsNeocentromeres and human artificial chromosomes: an unnatural act.Construction of neocentromere-based human minichromosomes by telomere-associated chromosomal truncation.Development of mammalian artificial chromosomes for the treatment of genetic diseases: Sandhoff and Krabbe diseases.Plant engineered minichromosomes and artificial chromosome platforms.Chromosome manipulation: a systematic approach toward understanding human chromosome structure and function.Human artificial chromosome-based gene delivery vectors for biomedicine and biotechnology.De novo formed satellite DNA-based mammalian artificial chromosomes and their possible applications.Using human artificial chromosomes to study centromere assembly and function.Insertion of a telomere repeat sequence into a mammalian gene causes chromosome instability.Construction of rice mini-chromosomes by telomere-mediated chromosomal truncation.Human artificial chromosomes constructed using the bottom-up strategy are stably maintained in mitosis and efficiently transmissible to progeny mice.Analysis of mitotic and expression properties of human neocentromere-based transchromosomes in mice.Construction of YAC-based mammalian artificial chromosomes.The simplicity of complex MACs.Human Artificial Chromosome with Regulated Centromere: A Tool for Genome and Cancer Studies
P2860
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P2860
Mini-chromosomes derived from the human Y chromosome by telomere directed chromosome breakage.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mini-chromosomes derived from ...... directed chromosome breakage.
@en
Mini-chromosomes derived from ...... directed chromosome breakage.
@nl
type
label
Mini-chromosomes derived from ...... directed chromosome breakage.
@en
Mini-chromosomes derived from ...... directed chromosome breakage.
@nl
prefLabel
Mini-chromosomes derived from ...... directed chromosome breakage.
@en
Mini-chromosomes derived from ...... directed chromosome breakage.
@nl
P2093
P2860
P356
P1476
Mini-chromosomes derived from ...... directed chromosome breakage.
@en
P2093
P2860
P304
P356
10.1073/PNAS.93.14.7125
P407
P577
1996-07-01T00:00:00Z