Functional reintroduction of human telomeres into mammalian cells.
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Targeting assay to study the cis functions of human telomeric proteins: evidence for inhibition of telomerase by TRF1 and for activation of telomere degradation by TRF2Rap1 affects the length and heterogeneity of human telomeresPOT1 and TRF2 cooperate to maintain telomeric integritySir proteins, Rif proteins, and Cdc13p bind Saccharomyces telomeres in vivo.ATM Kinase Is Required for Telomere Elongation in Mouse and Human CellsA human interstitial telomere associates in vivo with specific TRF2 and TIN2 proteinsEngineered plant minichromosomes: a bottom-up success?Telomere-mediated chromosomal truncation in maizeHuman artificial chromosomes generated by modification of a yeast artificial chromosome containing both human alpha satellite and single-copy DNA sequences.Trf1 is not required for proliferation or functional telomere maintenance in chicken DT40 cells.Developmentally regulated initiation of DNA synthesis by telomerase: evidence for factor-assisted de novo telomere formation.Germ-line effects of a mutator, mu2, in Drosophila melanogaster.Telomere dynamics in an immortal human cell line.Human telomeric position effect is determined by chromosomal context and telomeric chromatin integrity.Chromosome instability as a result of double-strand breaks near telomeres in mouse embryonic stem cellsDNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line.Telomere-regulating genes and the telomere interactome in familial cancers.The relationship between spontaneous telomere loss and chromosome instability in a human tumor cell line.Cloning and molecular characterization of a novel chromosome specific centromere sequence of Chinese hamster.Isolation of telomeric DNA from the filamentous fungus Podospora anserina and construction of a self-replicating linear plasmid showing high transformation frequency.A protein which specifically binds to single stranded TTAGGGn repeatsA human artificial chromosome recapitulates the metabolism of native telomeres in mammalian cellsIllegitimate DNA integration in mammalian cells.Stringent sequence requirements for the formation of human telomeres.RAP1 stimulates single- to double-strand association of yeast telomeric DNA: implications for telomere-telomere interactionsConstruction of neocentromere-based human minichromosomes by telomere-associated chromosomal truncation.hnRNP A2/B1 binds specifically to single stranded vertebrate telomeric repeat TTAGGGnChromosome healing in mouse embryonic stem cells.Epigenetic and phenotypic consequences of a truncation disrupting the imprinted domain on distal mouse chromosome 7.HeT-A, a transposable element specifically involved in "healing" broken chromosome ends in Drosophila melanogaster.Plant engineered minichromosomes and artificial chromosome platforms.Chromosome manipulation: a systematic approach toward understanding human chromosome structure and function.Mini-chromosomes derived from the human Y chromosome by telomere directed chromosome breakage.Generation of a human X-derived minichromosome using telomere-associated chromosome fragmentation.Towards the development of better crops by genetic transformation using engineered plant chromosomes.Engineering of plant chromosomes.Epigenetic regulatory elements associate with specific histone modifications to prevent silencing of telomeric genes.The epigenetic regulation of autonomous replicons.Centromere Silencing Mechanisms.Insertion of a telomere repeat sequence into a mammalian gene causes chromosome instability.
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P2860
Functional reintroduction of human telomeres into mammalian cells.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Functional reintroduction of human telomeres into mammalian cells.
@en
Functional reintroduction of human telomeres into mammalian cells.
@nl
type
label
Functional reintroduction of human telomeres into mammalian cells.
@en
Functional reintroduction of human telomeres into mammalian cells.
@nl
prefLabel
Functional reintroduction of human telomeres into mammalian cells.
@en
Functional reintroduction of human telomeres into mammalian cells.
@nl
P2093
P2860
P356
P1476
Functional reintroduction of human telomeres into mammalian cells.
@en
P2093
P2860
P304
P356
10.1073/PNAS.88.16.7006
P407
P577
1991-08-01T00:00:00Z