Human immunodeficiency virus type 1 gp120 induces abnormal maturation and functional alterations of dendritic cells: a novel mechanism for AIDS pathogenesis.
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Soluble HLA-G inhibits myeloid dendritic cell function in HIV-1 infection by interacting with leukocyte immunoglobulin-like receptor B2Human immunodeficiency virus type 1 gp120 and other activation stimuli are highly effective in triggering alpha interferon and CC chemokine production in circulating plasmacytoid but not myeloid dendritic cells.An alternative and effective HIV vaccination approach based on inhibition of antigen presentation attenuators in dendritic cells.A Chimeric HIV-1 gp120 Fused with Vaccinia Virus 14K (A27) Protein as an HIV ImmunogenHIV-1 gp120 mannoses induce immunosuppressive responses from dendritic cells.Phosphatidylcholine-specific phospholipase C activation is required for CCR5-dependent, NF-kB-driven CCL2 secretion elicited in response to HIV-1 gp120 in human primary macrophages.Utilizing the FIV model to understand dendritic cell dysfunction and the potential role of dendritic cell immunization in HIV infection.Binding and transfer of human immunodeficiency virus by DC-SIGN+ cells in human rectal mucosa.Mutational escape in HIV-1 CTL epitopes leads to increased binding to inhibitory myelomonocytic MHC class I receptors.Human immunodeficiency virus type 1 Vpr impairs dendritic cell maturation and T-cell activation: implications for viral immune escape.R5-SHIV induces multiple defects in T cell function during early infection of rhesus macaques including accumulation of T reg cells in lymph nodesInnate immune recognition and activation during HIV infection.HIV-1 gp120 activates the STAT3/interleukin-6 axis in primary human monocyte-derived dendritic cellsFailure of HIV-exposed CD4+ T cells to activate dendritic cells is reversed by restoration of CD40/CD154 interactionsBinding of HIV-1 gp120 to DC-SIGN promotes ASK-1-dependent activation-induced apoptosis of human dendritic cells.HIV-1-induced impairment of dendritic cell cross talk with γδ T lymphocytes.HIV-1 gp120 inhibits TLR9-mediated activation and IFN-{alpha} secretion in plasmacytoid dendritic cells.How can HIV-type-1-Env immunogenicity be improved to facilitate antibody-based vaccine development?HIV-1 gp120 influences the expression of microRNAs in human monocyte-derived dendritic cells via STAT3 activationVaccine-delivered HIV envelope inhibits CD4(+) T-cell activation, a mechanism for poor HIV vaccine responses.Functional Impairment of Myeloid Dendritic Cells during Advanced Stage of HIV-1 Infection: Role of Factors Regulating Cytokine SignalingImmunomodulatory effects of HSV-2 infection on immature macaque dendritic cells modify innate and adaptive responsesEfficient inhibition of HIV-1 replication in human immature monocyte-derived dendritic cells by purified anti-HIV-1 IgG without induction of maturation.The Src kinase Lyn is required for CCR5 signaling in response to MIP-1beta and R5 HIV-1 gp120 in human macrophages.Dendritic cells infected with vpr-positive human immunodeficiency virus type 1 induce CD8+ T-cell apoptosis via upregulation of tumor necrosis factor alpha.Dendritic cells in viral pathogenesis: protective or defective?Characterization of the defective interaction between a subset of natural killer cells and dendritic cells in HIV-1 infection.A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cellsHIV-1 gp120-induced migration of dendritic cells is regulated by a novel kinase cascade involving Pyk2, p38 MAP kinase, and LSP1Secondary lymphoid organ homing phenotype of human myeloid dendritic cells disrupted by an intracellular oral pathogen.Enhancing immunogenicity and cross-reactivity of HIV-1 antigens by in vivo targeting to dendritic cells.Tissue dendritic cells as portals for HIV entry.HIV-1 gp120 impairs the induction of B cell responses by TLR9-activated plasmacytoid dendritic cells.HIV infection: focus on the innate immune cells.Herpes simplex virus type 1 induces CD83 degradation in mature dendritic cells with immediate-early kinetics via the cellular proteasome.Dendritic Cell Response to HIV-1 Is Controlled by Differentiation Programs in the Cells and Strain-Specific Properties of the Virus.Triggering of TLR-3, -4, NOD2, and DC-SIGN reduces viral replication and increases T-cell activation capacity of HIV-infected human dendritic cells.NKp30-dependent cytolysis of filovirus-infected human dendritic cells.Differential effects of HIV transmission from monocyte-derived dendritic cells vs. monocytes to IL-17+CD4+ T cells.Plasmacytoid and myeloid dendritic cells with a partial activation phenotype accumulate in lymphoid tissue during asymptomatic chronic HIV-1 infection
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Human immunodeficiency virus type 1 gp120 induces abnormal maturation and functional alterations of dendritic cells: a novel mechanism for AIDS pathogenesis.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 2004
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Human immunodeficiency virus t ...... chanism for AIDS pathogenesis.
@en
Human immunodeficiency virus t ...... chanism for AIDS pathogenesis.
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type
label
Human immunodeficiency virus t ...... chanism for AIDS pathogenesis.
@en
Human immunodeficiency virus t ...... chanism for AIDS pathogenesis.
@nl
prefLabel
Human immunodeficiency virus t ...... chanism for AIDS pathogenesis.
@en
Human immunodeficiency virus t ...... chanism for AIDS pathogenesis.
@nl
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Human immunodeficiency virus t ...... echanism for AIDS pathogenesis
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Cristina Purificato
Karim Donato
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10.1128/JVI.78.18.9763-9772.2004
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2004-09-01T00:00:00Z