Mycolactone subverts immunity by selectively blocking the Sec61 translocon.
about
Zika virus induces massive cytoplasmic vacuolization and paraptosis-like death in infected cells.Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export.Mycolactone reveals the substrate-driven complexity of Sec61-dependent transmembrane protein biogenesis.A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone.The chemistry and biology of mycolactones.An Update on Sec61 Channel Functions, Mechanisms, and Related Diseases.Mycolactone displays anti-inflammatory effects on the nervous system.Inhibitors of protein translocation across membranes of the secretory pathway: novel antimicrobial and anticancer agents.The potent effect of mycolactone on lipid membranes.Leveraging Chemotype-Specific Resistance for Drug Target Identification and Chemical Biology.ATG5 Promotes Death Signaling in Response to the Cyclic Depsipeptides Coibamide A and Apratoxin A.Inhibition of Sec61-dependent translocation by mycolactone uncouples the integrated stress response from ER stress, driving cytotoxicity via translational activation of ATF4.Modular total syntheses of mycolactone A/B and its [2H]-isotopologueProteomics Reveals Scope of Mycolactone-mediated Sec61 Blockade and Distinctive Stress SignatureBuruli Ulcer: a Review of the Current Knowledge
P2860
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P2860
Mycolactone subverts immunity by selectively blocking the Sec61 translocon.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Mycolactone subverts immunity by selectively blocking the Sec61 translocon.
@en
Mycolactone subverts immunity by selectively blocking the Sec61 translocon.
@nl
type
label
Mycolactone subverts immunity by selectively blocking the Sec61 translocon.
@en
Mycolactone subverts immunity by selectively blocking the Sec61 translocon.
@nl
prefLabel
Mycolactone subverts immunity by selectively blocking the Sec61 translocon.
@en
Mycolactone subverts immunity by selectively blocking the Sec61 translocon.
@nl
P2093
P2860
P50
P356
P1476
Mycolactone subverts immunity by selectively blocking the Sec61 translocon
@en
P2093
Fatoumata Niang
Jack Taunton
Ludivine Baron
Sarah Saint-Auret
P2860
P304
P356
10.1084/JEM.20160662
P407
P50
P577
2016-11-07T00:00:00Z