Pirh2: an E3 ligase with central roles in the regulation of cell cycle, DNA damage response, and differentiation
about
The Regulation of Tumor Suppressor p63 by the Ubiquitin-Proteasome SystemUSP28 is recruited to sites of DNA damage by the tandem BRCT domains of 53BP1 but plays a minor role in double-strand break metabolism.Molecular Analysis of the HOXA2-Dependent Degradation of RCHY1.COP1 enhances ubiquitin-mediated degradation of p27Kip1 to promote cancer cell growth.Molecular pathways: turning proteasomal protein degradation into a unique treatment approach.Further insight into BRUTUS domain composition and functionality.p53 down-regulates SARS coronavirus replication and is targeted by the SARS-unique domain and PLpro via E3 ubiquitin ligase RCHY1Screening for E3-ubiquitin ligase inhibitors: challenges and opportunities.Downregulation of Ubiquitin-conjugating Enzyme UBE2D3 Promotes Telomere Maintenance and Radioresistance of Eca-109 Human Esophageal Carcinoma Cells.High Expression of Pirh2 is Associated with Poor Prognosis in Glioma.Pirh2 mediates the sensitivity of myeloma cells to bortezomib via canonical NF-κB signaling pathway.Increased expression of E3 ubiquitin ligases targeting p53 in CLL patients with wild-type TP53 exhibits associations with clinical features of the disease.
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Pirh2: an E3 ligase with central roles in the regulation of cell cycle, DNA damage response, and differentiation
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 05 August 2013
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Pirh2: an E3 ligase with centr ...... response, and differentiation
@en
Pirh2: an E3 ligase with centr ...... response, and differentiation.
@nl
type
label
Pirh2: an E3 ligase with centr ...... response, and differentiation
@en
Pirh2: an E3 ligase with centr ...... response, and differentiation.
@nl
prefLabel
Pirh2: an E3 ligase with centr ...... response, and differentiation
@en
Pirh2: an E3 ligase with centr ...... response, and differentiation.
@nl
P2093
P2860
P356
P1433
P1476
Pirh2: an E3 ligase with centr ...... response, and differentiation
@en
P2093
Anne Hakem
Marie-jo Halaby
Razqallah Hakem
P2860
P304
P356
10.4161/CC.25785
P577
2013-08-05T00:00:00Z