Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformation
about
A strategy for isolation of cDNAs encoding proteins affecting human intestinal epithelial cell growth and differentiation: characterization of a novel gut-specific N-myristoylated annexinIsolation and sequence analysis of a novel human tyrosine kinase geneRNA dimerization defect in a Rous sarcoma virus matrix mutant.Shc and Enigma are both required for mitogenic signaling by Ret/ptc2.G alpha 12 and G alpha 13 subunits define a fourth class of G protein alpha subunitsAmino-terminal basic residues of Src mediate membrane binding through electrostatic interaction with acidic phospholipidsMolecular features of the viral and cellular Src kinases involved in interactions with the GTPase-activating protein.Two isoforms of murine hck, generated by utilization of alternative translational initiation codons, exhibit different patterns of subcellular localizationEnhanced signaling and morphological transformation by a membrane-localized derivative of the fibroblast growth factor receptor 3 kinase domainIdentification of a membrane-binding domain within the amino-terminal region of human immunodeficiency virus type 1 Gag protein which interacts with acidic phospholipidsSelective uncoupling of p120(ctn) from E-cadherin disrupts strong adhesionMolecular mechanics of calcium-myristoyl switchesProtein N-myristoylation in Escherichia coli: reconstitution of a eukaryotic protein modification in bacteria.Cloning, expression, and chromosome mapping of human galectin-7Myristylation alters DNA-binding activity and transactivation of FBR (gag-fos) proteinReplication of human immunodeficiency virus 1 and Moloney murine leukemia virus is inhibited by different heteroatom-containing analogs of myristic acidSTY, a tyrosine-phosphorylating enzyme with sequence homology to serine/threonine kinasesCellular FRET-Biosensors to Detect Membrane Targeting Inhibitors of N-Myristoylated ProteinsCloning and expression of rat liver CTP: phosphocholine cytidylyltransferase: an amphipathic protein that controls phosphatidylcholine synthesisMultiple cDNAs encoding the esk kinase predict transmembrane and intracellular enzyme isoformsSrc kinase activity and SH2 domain regulate the dynamics of Src association with lipid and protein targets.v-Src suppresses SHPS-1 expression via the Ras-MAP kinase pathway to promote the oncogenic growth of cells.The role of the Src homology domains in morphological transformation by v-srcAssociation of the amino-terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527.Identification and sequence analysis of cDNAs encoding a 110-kilodalton actin filament-associated pp60src substrate.Mutations in the SH3 domain of the src oncogene which decrease association of phosphatidylinositol 3'-kinase activity with pp60v-src and alter cellular morphology.Identification and characterization of a novel cytoskeleton-associated pp60src substrate.Glycoprotein tyrosine phosphorylation in Rous sarcoma virus-transformed chicken embryo fibroblasts.Transformation by pp60src or stimulation of cells with epidermal growth factor induces the stable association of tyrosine-phosphorylated cellular proteins with GTPase-activating protein.Differential modulation of plasminogen activator gene expression by oncogene-encoded protein tyrosine kinasesThe sites of phosphorylation by protein kinase C and an intact SH2 domain are required for the enhanced response to beta-adrenergic agonists in cells overexpressing c-srcConstitutive phosphorylation of the receptor for insulinlike growth factor I in cells transformed by the src oncogeneStable association of activated pp60src with two tyrosine-phosphorylated cellular proteinspp60c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-srcTransformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene.Association of p60src with Triton X-100-resistant cellular structure correlates with morphological transformation.Deletions and insertions within an amino-terminal domain of pp60v-src inactivate transformation and modulate membrane stabilityInhibition of the tyrosine kinase activity of v-src, v-fgr, and v-yes gene products by a monoclonal antibody which binds both amino and carboxy peptide fragments of pp60v-src.Dissecting motility signaling through activation of specific Src-effector complexesA murine fer testis-specific transcript (ferT) encodes a truncated Fer protein.
P2860
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P2860
Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformation
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 1985
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mutation of NH2-terminal glyci ...... d morphological transformation
@en
Mutation of NH2-terminal glyci ...... morphological transformation.
@nl
type
label
Mutation of NH2-terminal glyci ...... d morphological transformation
@en
Mutation of NH2-terminal glyci ...... morphological transformation.
@nl
prefLabel
Mutation of NH2-terminal glyci ...... d morphological transformation
@en
Mutation of NH2-terminal glyci ...... morphological transformation.
@nl
P2093
P2860
P356
P1476
Mutation of NH2-terminal glyci ...... d morphological transformation
@en
P2093
P2860
P304
P356
10.1073/PNAS.82.14.4625
P407
P577
1985-07-01T00:00:00Z