pp60c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-src
about
Src family kinases negatively regulate platelet-derived growth factor alpha receptor-dependent signaling and disease progressionTyrosine phosphorylation of selected secretory carrier membrane proteins, SCAMP1 and SCAMP3, and association with the EGF receptor.Tyrosine kinase signalling in breast cancer: epidermal growth factor receptor and c-Src interactions in breast cancer.The molecular rationale of Src inhibition in colorectal carcinomasThe epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and beta-cateninCsk-binding protein (Cbp) negatively regulates epidermal growth factor-induced cell transformation by controlling Src activationRegulation of SRC family kinases in human cancersBrk, a breast tumor-derived non-receptor protein-tyrosine kinase, sensitizes mammary epithelial cells to epidermal growth factorOverexpression of c-src enhances beta-adrenergic-induced cAMP accumulationThe C terminus of c-Src inhibits breast tumor cell growth by a kinase-independent mechanism.Cas mediates transcriptional activation of the serum response element by Src.Dissection of the molecular basis of pp60(v-src) induced gating of connexin 43 gap junction channels.Requirement for c-Src catalytic activity and the SH3 domain in platelet-derived growth factor BB and epidermal growth factor mitogenic signaling.The Src SH3 domain is required for DNA synthesis induced by platelet-derived growth factor and epidermal growth factor.Involvement of pp60c-src with two major signaling pathways in human breast cancer.Src family kinases and HER2 interactions in human breast cancer cell growth and survival.STAT5b, a Mediator of Synergism between c-Src and the Epidermal Growth Factor Receptor.Src-dependent tyrosine phosphorylation of non-muscle myosin heavy chain-IIA restricts Listeria monocytogenes cellular infectionPhosphorylation of Y845 on the epidermal growth factor receptor mediates binding to the mitochondrial protein cytochrome c oxidase subunit II.Transactivating agonists of the EGF receptor require Tyr 845 phosphorylation for induction of DNA synthesis.Phosphorylation and activation of epidermal growth factor receptors in cells transformed by the src oncogeneTransformation by pp60src or stimulation of cells with epidermal growth factor induces the stable association of tyrosine-phosphorylated cellular proteins with GTPase-activating protein.Tyrosine phosphorylation of three cellular proteins correlates with transformation of rat 1 cells by pp60src.Induction of apoptosis after expression of PYK2, a tyrosine kinase structurally related to focal adhesion kinase.c-Src regulates the simultaneous rearrangement of actin cytoskeleton, p190RhoGAP, and p120RasGAP following epidermal growth factor stimulationc-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGFA protein that is highly related to GTPase-activating protein-associated p62 complexes with phospholipase C gammaThe sites of phosphorylation by protein kinase C and an intact SH2 domain are required for the enhanced response to beta-adrenergic agonists in cells overexpressing c-srcConstitutive phosphorylation of the receptor for insulinlike growth factor I in cells transformed by the src oncogenePhosphotyrosine (p-Tyr)-dependent and -independent mechanisms of p190 RhoGAP-p120 RasGAP interaction: Tyr 1105 of p190, a substrate for c-Src, is the sole p-Tyr mediator of complex formationPotentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: implications for the etiology of multiple human cancersComplex formation with focal adhesion kinase: A mechanism to regulate activity and subcellular localization of Src kinases.Mechanism of biological synergy between cellular Src and epidermal growth factor receptorIdentification of the in vitro phosphorylation sites on Gs alpha mediated by pp60c-src.Activation of Fyn tyrosine kinase upon secretagogue stimulation of bovine chromaffin cells.Characterization of human epidermal growth factor receptor and c-Src interactions in human breast tumor cells.Protein myristoylation in health and disease.Kinase inhibitors in cancer therapy: a look ahead.Src inhibitors: genomics to therapeutics.Src promotes destruction of c-Cbl: implications for oncogenic synergy between Src and growth factor receptors
P2860
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P2860
pp60c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-src
description
1989 nî lūn-bûn
@nan
1989 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
pp60c-src tyrosine kinase, myr ...... in cells overexpressing c-src
@ast
pp60c-src tyrosine kinase, myr ...... in cells overexpressing c-src
@en
type
label
pp60c-src tyrosine kinase, myr ...... in cells overexpressing c-src
@ast
pp60c-src tyrosine kinase, myr ...... in cells overexpressing c-src
@en
prefLabel
pp60c-src tyrosine kinase, myr ...... in cells overexpressing c-src
@ast
pp60c-src tyrosine kinase, myr ...... in cells overexpressing c-src
@en
P2093
P2860
P356
P1476
pp60c-src tyrosine kinase, myr ...... in cells overexpressing c-src
@en
P2093
D K Luttrell
J T Parsons
L K Wilson
S J Parsons
P2860
P304
P356
10.1128/MCB.9.4.1536
P407
P577
1989-04-01T00:00:00Z