Glucose promotes breast cancer aggression and reduces metformin efficacy.
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Glucose metabolism in gastric cancer: The cutting-edgeMedium Renewal Blocks Anti-Proliferative Effects of Metformin in Cultured MDA-MB-231 Breast Cancer CellsMetformin suppresses triple-negative breast cancer stem cells by targeting KLF5 for degradation.Hyperglycemia, a neglected factor during cancer progressionEffect of genetic variants and traits related to glucose metabolism and their interaction with obesity on breast and colorectal cancer risk among postmenopausal women.Estrogen Receptor-β and the Insulin-Like Growth Factor Axis as Potential Therapeutic Targets for Triple-Negative Breast Cancer.TAp73 promotes anti-senescence-anabolism not proliferation.Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion currentTumor mechanics and metabolic dysfunction.Metformin Induces Apoptosis and Downregulates Pyruvate Kinase M2 in Breast Cancer Cells Only When Grown in Nutrient-Poor Conditions.Metformin-induced killing of triple-negative breast cancer cells is mediated by reduction in fatty acid synthase via miRNA-193bAnti-tumor effects of everolimus and metformin are complementary and glucose-dependent in breast cancer cellsHyperglycemia-induced metabolic compensation inhibits metformin sensitivity in ovarian cancerLrp5 Has a Wnt-Independent Role in Glucose Uptake and Growth for Mammary Epithelial CellsLow glucose dependent decrease of apoptosis and induction of autophagy in breast cancer MCF-7 cells.The cell-autonomous mechanisms underlying the activity of metformin as an anticancer drugMetformin and cancer: Quo vadis et cui bono?Microparticulate and nanoparticulate drug delivery systems for metformin hydrochloride.Metabolic profiling of triple-negative breast cancer cells reveals metabolic vulnerabilities.Metformin attenuates transforming growth factor beta (TGF-β) mediated oncogenesis in mesenchymal stem-like/claudin-low triple negative breast cancer.Metformin in pancreatic cancer treatment: from clinical trials through basic research to biomarker quantification.Glucose-deprivation increases thyroid cancer cells sensitivity to metformin.Potential and real 'antineoplastic' and metabolic effect of metformin in diabetic and nondiabetic postmenopausal females.Essential role for non-canonical poly(A) polymerase GLD4 in cytoplasmic polyadenylation and carbohydrate metabolism.Recent advances in the use of metformin: can treating diabetes prevent breast cancer?Model-based unsupervised learning informs metformin-induced cell-migration inhibition through an AMPK-independent mechanism in breast cancerScreening Novel Molecular Targets of Metformin in Breast Cancer by Proteomic Approach.Metformin sensitizes triple-negative breast cancer to proapoptotic TRAIL receptor agonists by suppressing XIAP expression.Metformin synergistically suppress tumor growth with doxorubicin and reverse drug resistance by inhibiting the expression and function of P-glycoprotein in MCF7/ADR cells and xenograft models.Hyperglycemia and aberrant O-GlcNAcylation: contributions to tumor progression.Epsilon-aminocaproic acid prevents high glucose and insulin induced-invasiveness in MDA-MB-231 breast cancer cells, modulating the plasminogen activator system.Metabolic changes associated with metformin potentiates Bcl-2 inhibitor, Venetoclax, and CDK9 inhibitor, BAY1143572 and reduces viability of lymphoma cells.Pleiotropic Effects of Metformin on Cancer
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Glucose promotes breast cancer aggression and reduces metformin efficacy.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 03 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Glucose promotes breast cancer aggression and reduces metformin efficacy.
@en
Glucose promotes breast cancer aggression and reduces metformin efficacy.
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type
label
Glucose promotes breast cancer aggression and reduces metformin efficacy.
@en
Glucose promotes breast cancer aggression and reduces metformin efficacy.
@nl
prefLabel
Glucose promotes breast cancer aggression and reduces metformin efficacy.
@en
Glucose promotes breast cancer aggression and reduces metformin efficacy.
@nl
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P921
P356
P1433
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Glucose promotes breast cancer aggression and reduces metformin efficacy
@en
P2093
Ann D Thor
Jennifer K Richer
Reema Wahdan-Alaswad
Steven M Anderson
Susan M Edgerton
Xin-Sheng Deng
Zeying Fan
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P304
P356
10.4161/CC.26641
P577
2013-10-03T00:00:00Z