Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis - Wikidata - awgldk - TriplyDB

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

http://www.wikidata.org/entity/Q37527786

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Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancer Defining the sister rat mammary tumor cell lines HH-16 cl.2/1 and HH-16.cl.4 as an in vitro cell model for Erbb2 Spatio-temporal composition of the mitotic Chromosomal Passenger Complex detected using in situ proximity ligation assay The CHK2-BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cells MTR120/KIAA1383, a novel microtubule-associated protein, promotes microtubule stability and ensures cytokinesis A dual role for UVRAG in maintaining chromosomal stability independent of autophagy A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging Kinetochore-microtubule interactions: steps towards bi-orientation Upregulation of Cyclin B1 by miRNA and its implications in cancer Maintaining Genome Stability in Defiance of Mitotic DNA Damage Aneuploidy in stem cells Targeting the Mitotic Catastrophe Signaling Pathway in Cancer Patterns of Chromosomal Aberrations in Solid Tumors Endoreplication and polyploidy: insights into development and disease Aurora B hyperactivation by Bub1 overexpression promotes chromosome missegregation Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis Yeast: a simple model system to study complex phenomena of aneuploidy Reconstituting the kinetochore–microtubule interface: what, why, and how Liquid biopsies: genotyping circulating tumor DNA Aneuploidy in pluripotent stem cells and implications for cancerous transformation SUMOylation in control of accurate chromosome segregation during mitosis Mitotic Spindle Disruption by Alternating Electric Fields Leads to Improper Chromosome Segregation and Mitotic Catastrophe in Cancer Cells.Cellular and Molecular Features of Developmentally Programmed Genome Rearrangement in a Vertebrate (Sea Lamprey: Petromyzon marinus)Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability.Aneuploidy-induced cellular stresses limit autophagic degradation.Mitotic catastrophe occurs in the absence of apoptosis in p53-null cells with a defective G1 checkpoint Predisposition to cancer caused by genetic and functional defects of mammalian Atad5 Stable kinetochore-microtubule attachment is sufficient to silence the spindle assembly checkpoint in human cells Cdc20 is critical for meiosis I and fertility of female mice Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function Transcriptional control of mitosis: deregulation and cancer Chromokinesin Kid and kinetochore kinesin CENP-E differentially support chromosome congression without end-on attachment to microtubules Deficiency in the nuclear-related factor erythroid 2 transcription factor (Nrf1) leads to genetic instability Identification of aneuploidy-tolerating mutations Chromosome tips damaged in anaphase inhibit cytokinesis Pre-clinical drug prioritization via prognosis-guided genetic interaction networks Identification of a predominant co-regulation among kinetochore genes, prospective regulatory elements, and association with genomic instability Quantitative mass spectrometry analysis reveals similar substrate consensus motif for human Mps1 kinase and Plk1 Reprogramming to pluripotency can conceal somatic cell chromosomal instability Cycles and the qualitative evolution of chemical systems

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Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

http://www.wikidata.org/entity/Q37527786

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on July 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

@en

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis.

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type

label

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

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Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis.

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prefLabel

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

@en

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis.

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Nature Reviews Molecular Cell Biology

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Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

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Andrew J Holland

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Don W Cleveland

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P2860

The Polo kinase Plk4 functions in centriole duplication

sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1

Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss

Mutations of mitotic checkpoint genes in human cancers

Genome stability is ensured by temporal control of kinetochore-microtubule dynamics

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint.

Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis

The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores

Aneuploidy: cells losing their balance

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478-487

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scholarly article

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10.1038/NRM2718

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7

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10

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2009-07-01T00:00:00Z

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26311364

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1024297992

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19546858

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3154738

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