Dynamics of survival of motor neuron (SMN) protein interaction with the mRNA-binding protein IMP1 facilitates its trafficking into motor neuron axons.
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The Survival of Motor Neuron Protein Acts as a Molecular Chaperone for mRNP AssemblyAssays for the identification and prioritization of drug candidates for spinal muscular atrophySubcellular transcriptome alterations in a cell culture model of spinal muscular atrophy point to widespread defects in axonal growth and presynaptic differentiation.Presynaptic localization of Smn and hnRNP R in axon terminals of embryonic and postnatal mouse motoneuronsorthoFind Facilitates the Discovery of Homologous and Orthologous Proteins.Abnormal mitochondrial transport and morphology as early pathological changes in human models of spinal muscular atrophy.Deficiency of the Survival of Motor Neuron Protein Impairs mRNA Localization and Local Translation in the Growth Cone of Motor Neurons.Dysregulation of mRNA Localization and Translation in Genetic DiseaseSMN-targeted therapeutics for spinal muscular atrophy: are we SMArt enough yet?SMN control of RNP assembly: from post-transcriptional gene regulation to motor neuron disease.Developing therapies for spinal muscular atrophy.A novel role for CARM1 in promoting nonsense-mediated mRNA decay: potential implications for spinal muscular atrophy.ALS Along the Axons - Expression of Coding and Noncoding RNA Differs in Axons of ALS models.Regulation of neuronal gene expression by local axonal translation.Diverse role of survival motor neuron protein.MotomiRs: miRNAs in Motor Neuron Function and Disease.Developmental regulation of SMN expression: pathophysiological implications and perspectives for therapy development in spinal muscular atrophy.Motoneuron development influences dorsal root ganglia survival and Schwann cell development in a vertebrate model of spinal muscular atrophy.miRNA in spinal muscular atrophy pathogenesis and therapy.SMN regulation in SMA and in response to stress: new paradigms and therapeutic possibilities.mRNP assembly, axonal transport, and local translation in neurodegenerative diseases.Neurochondrin interacts with the SMN protein suggesting a novel mechanism for Spinal Muscular Atrophy pathology.Blocking p62-dependent SMN degradation ameliorates spinal muscular atrophy disease phenotypesCell-type-specific miR-431 dysregulation in a motor neuron model of spinal muscular atrophyIntroduction to the special issue on local protein synthesis in axonsCue-Polarized Transport of β-actin mRNA Depends on 3'UTR and Microtubules in Live Growth ConesUnraveling the Pathways to Neuronal Homeostasis and Disease: Mechanistic Insights into the Role of RNA-Binding Proteins and Associated Factors
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Dynamics of survival of motor neuron (SMN) protein interaction with the mRNA-binding protein IMP1 facilitates its trafficking into motor neuron axons.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 04 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Dynamics of survival of motor ...... cking into motor neuron axons.
@en
Dynamics of survival of motor neuron
@nl
type
label
Dynamics of survival of motor ...... cking into motor neuron axons.
@en
Dynamics of survival of motor neuron
@nl
prefLabel
Dynamics of survival of motor ...... cking into motor neuron axons.
@en
Dynamics of survival of motor neuron
@nl
P2093
P2860
P356
P1476
Dynamics of survival of motor ...... cking into motor neuron axons.
@en
P2093
Claudia Fallini
Gary J Bassell
Honglai Zhang
Jeremy P Rouanet
Paul G Donlin-Asp
Robert H Singer
P2860
P304
P356
10.1002/DNEU.22111
P577
2013-10-04T00:00:00Z