An influenza A virus containing influenza B virus 5' and 3' noncoding regions on the neuraminidase gene is attenuated in mice.
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Influenza A and B virus intertypic reassortment through compatible viral packaging signals.Improvement of influenza vaccine strain A/Vietnam/1194/2004 (H5N1) growth with the neuraminidase packaging sequence from A/Puerto Rico/8/34.Attenuation of bunyavirus replication by rearrangement of viral coding and noncoding sequences.Role of alpha/beta interferon in Venezuelan equine encephalitis virus pathogenesis: effect of an attenuating mutation in the 5' untranslated region.Contribution of the human parainfluenza virus type 3 HN-receptor interaction to pathogenesis in vivo.Disruption of the viral polymerase complex assembly as a novel approach to attenuate influenza A virus.Influenza vaccines: present and future.PB2 segment promotes high-pathogenicity of H5N1 avian influenza viruses in mice.Generation of influenza A viruses with chimeric (type A/B) hemagglutinins.Virtual screening of gene expression regulatory sites in non-coding regions of the infectious salmon anemia virus.Chimeric influenza A viruses with a functional influenza B virus neuraminidase or hemagglutinin.Influenza B viruses with site-specific mutations introduced into the HA gene.Reverse genetics system for generation of an influenza A virus mutant containing a deletion of the carboxyl-terminal residue of M2 protein.Mucosal model of immunization against human immunodeficiency virus type 1 with a chimeric influenza virusPalmitylation of the influenza virus hemagglutinin (H3) is not essential for virus assembly or infectivitySegment-specific noncoding sequences of the influenza virus genome RNA are involved in the specific competition between defective interfering RNA and its progenitor RNA segment at the virion assembly stepThe role of reverse genetics in the development of vaccines against respiratory viruses.Avian influenza virus: prospects for prevention and control by vaccination.Heterologous influenza vRNA segments with identical non-coding sequences stimulate viral RNA replication in trans.Mutational analysis of the conserved motifs of influenza A virus polymerase basic protein 1Reverse genetics provides direct evidence for a correlation of hemagglutinin cleavability and virulence of an avian influenza A virus.Cross-neutralizing activity against divergent human immunodeficiency virus type 1 isolates induced by the gp41 sequence ELDKWAS.Biologic importance of neuraminidase stalk length in influenza A virusRescue of synthetic analogs of genomic RNA and replicative-intermediate RNA of human parainfluenza virus type 3.Chimeric influenza virus induces neutralizing antibodies and cytotoxic T cells against human immunodeficiency virus type 1Glycosylation of neuraminidase determines the neurovirulence of influenza A/WSN/33 virus.Mutations in the cytoplasmic tail of influenza A virus neuraminidase affect incorporation into virions.Rescue of an influenza A virus wild-type PB2 gene and a mutant derivative bearing a site-specific temperature-sensitive and attenuating mutation.Transfection-mediated recombination of influenza A virusMutational analysis of the promoter required for influenza virus virion RNA synthesis.Attenuation of influenza A virus by insertion of a foreign epitope into the neuraminidase.Mechanism of attenuation of a chimeric influenza A/B transfectant virus.Limited compatibility between the RNA polymerase components of influenza virus type A and B.Dynamics of virus shedding and antibody responses in influenza A virus-infected feral swineTransfectant influenza A viruses are effective recombinant immunogens in the treatment of experimental cancerThe hemagglutinin-neuraminidase protein of Newcastle disease virus determines tropism and virulence.Use of single-gene reassortant viruses to study the role of avian influenza A virus genes in attenuation of wild-type human influenza A virus for squirrel monkeys and adult human volunteers.A single nucleotide change in the 5' noncoding region of Sindbis virus confers neurovirulence in rats.The N-terminal extension of the influenza B virus nucleoprotein is not required for nuclear accumulation or the expression and replication of a model RNAA reverse genetics approach for recovery of recombinant influenza B viruses entirely from cDNA.
P2860
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P2860
An influenza A virus containing influenza B virus 5' and 3' noncoding regions on the neuraminidase gene is attenuated in mice.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
An influenza A virus containin ...... se gene is attenuated in mice.
@en
An influenza A virus containin ...... se gene is attenuated in mice.
@nl
type
label
An influenza A virus containin ...... se gene is attenuated in mice.
@en
An influenza A virus containin ...... se gene is attenuated in mice.
@nl
prefLabel
An influenza A virus containin ...... se gene is attenuated in mice.
@en
An influenza A virus containin ...... se gene is attenuated in mice.
@nl
P2093
P2860
P356
P1476
An influenza A virus containin ...... se gene is attenuated in mice.
@en
P2093
P2860
P304
P356
10.1073/PNAS.88.12.5177
P407
P577
1991-06-01T00:00:00Z