An antipeptide antibody that specifically inhibits insulin receptor autophosphorylation and protein kinase activity.
about
Antibody binding to the juxtamembrane region of the insulin receptor alters receptor affinity.A monoclonal anti-peptide antibody reacting with the insulin receptor beta-subunit. Characterization of the antibody and its epitope and use in immunoaffinity purification of intact receptorsImmunological demonstration of the accumulation of insulin, but not insulin receptors, in nuclei of insulin-treated cells.Another version of the human insulin receptor kinase domain: expression, purification, and characterization.Insulin receptor function in fibroblasts from patients with leprechaunism. Differential alterations in binding, autophosphorylation, kinase activity, and receptor-mediated internalization.Isolation of a Drosophila genomic sequence homologous to the kinase domain of the human insulin receptor and detection of the phosphorylated Drosophila receptor with an anti-peptide antibodyInsulin receptors internalize by a rapid, saturable pathway requiring receptor autophosphorylation and an intact juxtamembrane regionInsulin and insulinlike growth factor 1 (IGF-1) receptors during central nervous system development: expression of two immunologically distinct IGF-1 receptor beta subunits.Structure and ligand specificity of the Drosophila melanogaster insulin receptorMolecular basis of the activation of the tumorigenic potential of Gag-insulin receptor chimeras.Antibodies to the insulin receptor as tools in the study of receptor structure and function.The insulin receptor: structure and function.The insulin receptor and the molecular mechanism of insulin action.Distinct beta-subunits are present in hybrid insulin-like-growth-factor-1 receptors in the central nervous system.Insulin stimulates proteolysis of the alpha-subunit, but not the beta-subunit, of its receptor at the cell surface in rat liver.Analysis of acetylcholine receptor phosphorylation sites using antibodies to synthetic peptides and monoclonal antibodies.Antibodies to insulin receptor tyrosine kinase stimulate its activity towards exogenous substrates without inducing receptor autophosphorylation.
P2860
Q30465526-1E96ECD4-6003-47D5-BF5B-832DF222A078Q31145358-AADB039E-2D3B-4A7E-B0E1-43BDC4FA9D2DQ34301064-3D91136C-9448-4FDC-B724-05B11DA7BB64Q34311602-B182E242-EBF6-45C2-8CF6-72EE570AAE4FQ35591798-BAFFB737-56FB-40A7-899F-F6CFD61ED5F6Q35614246-8AAD8469-05E8-487D-BBF8-B828C69A76E3Q36530542-2B461C8D-F4DA-4A9E-A906-A0F5180C729FQ36769052-BE9CE514-AFB3-4CB9-8D8B-5CFDE15A1380Q36919392-0268C3EA-5AC5-49B1-9DA2-C03B0287E898Q37388329-02B16DD7-8A68-42BD-B332-229576A6C51DQ38182083-53CA4022-41D4-46DB-93BE-79899019E046Q38270837-B641129F-CFED-4280-9686-DC994F574317Q39527320-9D191B8E-1C50-47D0-B444-7F83B0EB105FQ41935155-D27D387D-40B9-4026-B0A8-7F95C95553F6Q42088881-0EEF6792-80FE-453E-91A5-7848E122547DQ42574941-025CB40F-D078-4DBD-9929-7F78162F018FQ42836425-1BFB930F-2912-4DA3-B7AC-724C4B62BC8A
P2860
An antipeptide antibody that specifically inhibits insulin receptor autophosphorylation and protein kinase activity.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 1985
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
An antipeptide antibody that s ...... n and protein kinase activity.
@en
An antipeptide antibody that s ...... n and protein kinase activity.
@nl
type
label
An antipeptide antibody that s ...... n and protein kinase activity.
@en
An antipeptide antibody that s ...... n and protein kinase activity.
@nl
prefLabel
An antipeptide antibody that s ...... n and protein kinase activity.
@en
An antipeptide antibody that s ...... n and protein kinase activity.
@nl
P2093
P2860
P356
P1476
An antipeptide antibody that s ...... n and protein kinase activity.
@en
P2093
E T Kaiser
H N Bramson
L Petruzzelli
P2860
P304
P356
10.1073/PNAS.82.23.7899
P407
P577
1985-12-01T00:00:00Z