FAS-associated factor 1 (FAF1): diverse functions and implications for oncogenesis.
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Crystal structure of FAF1 UBX domain in complex with p97/VCP N domain reveals a conformational change in the conserved FcisP touch-turn motif of UBX domainUBXD Proteins: A Family of Proteins with Diverse Functions in CancerFocal DNA copy number changes in neuroblastoma target MYCN regulated genesmiR-24 regulates apoptosis by targeting the open reading frame (ORF) region of FAF1 in cancer cellsFas-associated factor 1 inhibits tumor growth by suppressing Helicobacter pylori-induced activation of NF-κB signaling in human gastric carcinomaCharacterization of the genomic features and expressed fusion genes in micropapillary carcinomas of the breast.Allelotyping identification of genomic alterations in rectal chromosomally unstable tumors without preoperative treatment.The expression of FAS-associated factor 1 and heat shock protein 70 in ovarian cancer.Molecular Analysis of a Recurrent Sarcoma Identifies a Mutation in FAF1MicroRNA in prostate cancer: functional importance and potential as circulating biomarkers.SUMO-Enriched Proteome for Drosophila Innate Immune Response.Fas-associated factor 1 is a scaffold protein that promotes β-transducin repeat-containing protein (β-TrCP)-mediated β-catenin ubiquitination and degradationTransposon mutagenesis identifies genes that transform neural stem cells into glioma-initiating cells.MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199.Reduced FAF1 Expression and Helicobacter Infection: Correlations with Clinicopathological Features in Gastric Cancer.Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression.UAS domain of Ubxd8 and FAF1 polymerizes upon interaction with long-chain unsaturated fatty acids3'-hydroxy-3,4,5,4'-tetramethoxystilbene, the metabolite of resveratrol analogue DMU-212, inhibits ovarian cancer cell growth in vitro and in a mice xenograft model.Genetic variants in fas signaling pathway genes and risk of gastric cancer.Genetic determinants of neuronal vulnerability to apoptosis.CUL-2LRR-1 and UBXN-3 drive replisome disassembly during DNA replication termination and mitosisStrategic role of the ubiquitin-dependent segregase p97 (VCP or Cdc48) in DNA replication.The p97-FAF1 protein complex reveals a common mode of p97 adaptor binding.Crystallization and preliminary X-ray crystallographic analysis of the hexameric human p97/VCP ND1 fragment in complex with the UBX domain of human FAF1.Emerging role of DUBs in tumor metastasis and apoptosis: Therapeutic implication.FAF1 mediates regulated necrosis through PARP1 activation upon oxidative stress leading to dopaminergic neurodegenerationCrystallization and preliminary X-ray crystallographic analysis of human FAF1 UBX domain.Fas-associated factor 1 plays a negative regulatory role in the antibacterial immunity of Locusta migratoria.Sanguinarine exhibits antitumor activity via up-regulation of Fas-associated factor 1 in non-small cell lung cancer.
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FAS-associated factor 1 (FAF1): diverse functions and implications for oncogenesis.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 16 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
FAS-associated factor 1 (FAF1): diverse functions and implications for oncogenesis.
@en
FAS-associated factor 1
@nl
type
label
FAS-associated factor 1 (FAF1): diverse functions and implications for oncogenesis.
@en
FAS-associated factor 1
@nl
prefLabel
FAS-associated factor 1 (FAF1): diverse functions and implications for oncogenesis.
@en
FAS-associated factor 1
@nl
P2093
P2860
P356
P1433
P1476
FAS-associated factor 1 (FAF1): diverse functions and implications for oncogenesis.
@en
P2093
Craig W Menges
Deborah A Altomare
Joseph R Testa
P2860
P304
P356
10.4161/CC.8.16.9280
P577
2009-08-16T00:00:00Z