Mass defect filter technique and its applications to drug metabolite identification by high-resolution mass spectrometry.
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In vitro and in vivo metabolism and inhibitory activities of vasicine, a potent acetylcholinesterase and butyrylcholinesterase inhibitorTrends in the application of high-resolution mass spectrometry for human biomonitoring: An analytical primer to studying the environmental chemical space of the human exposomeData acquisition and data mining techniques for metabolite identification using LC coupled to high-resolution MS.Identification of urinary metabolites of imperatorin with a single run on an LC/Triple TOF system based on multiple mass defect filter data acquisition and multiple data mining techniques.Post-acquisition data processing for the screening of transformation products of different organic contaminants. Two-year monitoring of river water using LC-ESI-QTOF-MS and GCxGC-EI-TOF-MS.Metabolite identification of the antimalarial piperaquine in vivo using liquid chromatography-high-resolution mass spectrometry in combination with multiple data-mining tools in tandem.Advanced Multidimensional Separations in Mass Spectrometry: Navigating the Big Data Deluge.Identification of Metabolites of 6'-Hydroxy-3,4,5,2',4'-pentamethoxychalcone in Rats by a Combination of Ultra-High-Performance Liquid Chromatography with Linear Ion Trap-Orbitrap Mass Spectrometry Based on Multiple Data Processing Techniques.xMSannotator: An R Package for Network-Based Annotation of High-Resolution Metabolomics Data.An efficient data-filtering strategy for easy metabolite detection from the direct analysis of a biological fluid using Fourier transform mass spectrometry.Enhanced dereplication of fungal cultures via use of mass defect filtering.Exposure Marker Discovery of Phthalates Using Mass Spectrometry.High-resolution chromatography/time-of-flight MSE with in silico data mining is an information-rich approach to reactive metabolite screening.Metabolite identification of triptolide by data-dependent accurate mass spectrometric analysis in combination with online hydrogen/deuterium exchange and multiple data-mining techniques.Comparative metabolism of cyclophosphamide and ifosfamide in the mouse using UPLC-ESI-QTOFMS-based metabolomics.Application of LC-high-resolution MS with 'intelligent' data mining tools for screening reactive drug metabolites.Bioinformatics Tools for Mass Spectroscopy-Based Metabolomic Data Processing and Analysis.Detection and characterization of ticlopidine conjugates in rat bile using high-resolution mass spectrometry: applications of various data acquisition and processing tools.Integration of untargeted metabolomics with transcriptomics reveals active metabolic pathways.Identification of xenobiotic metabolites from biological fluids using flow injection analysis high-resolution mass spectrometry and post-acquisition data filtering.High Resolution Mass Spectrometry of Polyfluorinated Polyether-Based Formulation.Metabolism profiles of nuciferine in rats using ultrafast liquid chromatography with tandem mass spectrometry.Estimation of nitric oxide synthase activity via liquid chromatography/tandem mass spectrometric assay determination of 15N3 -citrulline in biological samples.In vivo metabolite identification of acotiamide in rats using ultra-performance liquid chromatography-quadrupole/time-of-flight mass spectrometry.Urinary antihypertensive drug metabolite screening using molecular networking coupled to high-resolution mass spectrometry fragmentationComputational Metabolomics: A Framework for the Million Metabolome.NMR spectroscopy as a tool to close the gap on metabolite characterization under MIST.Drug metabolite profiling and identification by high-resolution mass spectrometry.Bioanalytical aspects of clinical mass balance studies in oncology.Using high-resolution quadrupole TOF technology in DMPK analyses.Recent advances in metabolite identification and quantitative bioanalysis by LC-Q-TOF MS.An introduction to hybrid ion trap/time-of-flight mass spectrometry coupled with liquid chromatography applied to drug metabolism studies.Metabolite structure analysis by high-resolution MS: supporting drug-development studies.Software automation tools for increased throughput metabolic soft-spot identification in early drug discovery.Application and challenges in using LC-MS assays for absolute quantitative analysis of therapeutic proteins in drug discovery.Applications of mass spectrometry in drug metabolism: 50 years of progress.Post-acquisition data mining techniques for LC-MS/MS-acquired data in drug metabolite identification.A high-resolution accurate mass (HR/AM) approach to identification, profiling and characterization of in vitro nefazodone metabolites using a hybrid quadrupole Orbitrap (Q-Exactive).Recent developments in software tools for high-throughput in vitro ADME support with high-resolution MS.Applications of high-resolution MS in bioanalysis.
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P2860
Mass defect filter technique and its applications to drug metabolite identification by high-resolution mass spectrometry.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mass defect filter technique a ...... -resolution mass spectrometry.
@en
Mass defect filter technique a ...... -resolution mass spectrometry.
@nl
type
label
Mass defect filter technique a ...... -resolution mass spectrometry.
@en
Mass defect filter technique a ...... -resolution mass spectrometry.
@nl
prefLabel
Mass defect filter technique a ...... -resolution mass spectrometry.
@en
Mass defect filter technique a ...... -resolution mass spectrometry.
@nl
P2093
P356
P1476
Mass defect filter technique a ...... -resolution mass spectrometry.
@en
P2093
Donglu Zhang
Haiying Zhang
Kenneth Ray
Mingshe Zhu
P304
P356
10.1002/JMS.1610
P577
2009-07-01T00:00:00Z