Drug metabolite profiling and identification by high-resolution mass spectrometry.
about
MassCascade: Visual Programming for LC-MS Data Processing in MetabolomicsTrends in the application of high-resolution mass spectrometry for human biomonitoring: An analytical primer to studying the environmental chemical space of the human exposomeExploring the utility of high-resolution MS with post-acquisition data mining for simultaneous exogenous and endogenous metabolite profiling.Data acquisition and data mining techniques for metabolite identification using LC coupled to high-resolution MS.Identification of urinary metabolites of imperatorin with a single run on an LC/Triple TOF system based on multiple mass defect filter data acquisition and multiple data mining techniques.Post-acquisition data processing for the screening of transformation products of different organic contaminants. Two-year monitoring of river water using LC-ESI-QTOF-MS and GCxGC-EI-TOF-MS.An accelerated background subtraction algorithm for processing high-resolution MS data and its application to metabolite identification.Exposure Marker Discovery of Phthalates Using Mass Spectrometry.Absorption, distribution, metabolism, and excretion of [14C]-dasotraline in humans.Qualitative-(semi)quantitative data acquisition of artemisinin and its metabolites in rat plasma using an LTQ/Orbitrap mass spectrometer.Simultaneous screening of glutathione and cyanide adducts using precursor ion and neutral loss scans-dependent product ion spectral acquisition and data mining tools.Integrated quantitative and qualitative workflow for in vivo bioanalytical support in drug discovery using hybrid Q-TOF-MS.Metabolic profiling of new synthetic cannabinoids AMB and 5F-AMB by human hepatocyte and liver microsome incubations and high-resolution mass spectrometry.Technologies and strategies to characterize and quantitate metabolites in drug discovery and development.The development and assessment of high-throughput mass spectrometry-based methods for the quantification of a nanoparticle drug delivery agent in cellular lysate.Systems medicine: evolution of systems biology from bench to bedsideAn Integrated Approach for Studying Exposure, Metabolism, and Disposition of Multiple Component Herbal Medicines Using High-Resolution Mass Spectrometry and Multiple Data Processing Tools.LC-high-resolution-MS/MS analysis of chemical compounds in rat plasma after oral administration of Nao-Mai-Tong and its individual herbs.Electrospray Quadrupole Travelling Wave Ion Mobility Time-of-Flight Mass Spectrometry for the Detection of Plasma Metabolome Changes Caused by Xanthohumol in Obese Zucker (fa/fa) Rats.Bioanalytical aspects of clinical mass balance studies in oncology.Current applications of high-resolution mass spectrometry in drug metabolism studies.Recent advances in metabolite identification and quantitative bioanalysis by LC-Q-TOF MS.Radiolabeled mass-balance excretion and metabolism studies in laboratory animals: a commentary on why they are still necessary.Biotransformation and biocatalysis: roles and applications in the discovery of antimalarials.An introduction to hybrid ion trap/time-of-flight mass spectrometry coupled with liquid chromatography applied to drug metabolism studies.Metabolite structure analysis by high-resolution MS: supporting drug-development studies.Network pharmacology strategies toward multi-target anticancer therapies: from computational models to experimental design principles.Software automation tools for increased throughput metabolic soft-spot identification in early drug discovery.Reflecting on a decade of metabolite screening and monitoring.Applications of mass spectrometry in drug metabolism: 50 years of progress.Post-acquisition data mining techniques for LC-MS/MS-acquired data in drug metabolite identification.Introduction: use of radioactive compounds in drug discovery and development.Site of Metabolism Prediction Based on ab initio Derived Atom Representations.An efficient liquid chromatography-high resolution mass spectrometry approach for the optimization of the metabolic stability of therapeutic peptides.Mass spectrometry-based proteomics in molecular diagnostics: discovery of cancer biomarkers using tissue culture.In vivo drug metabolite identification in preclinical ADME studies by means of UPLC/TWIMS/high resolution-QTOF MS(E) and control comparison: cost and benefit of vehicle-dosed control samples.Systematic and comprehensive strategy for metabolite profiling in bioanalysis using software-assisted HPLC-Q-TOF: magnoflorine as an example.One drop chemical derivatization--DESI-MS analysis for metabolite structure identification.Elucidation of the Biotransformation Pathways of a Galnac3-conjugated Antisense Oligonucleotide in Rats and Monkeys.Fragmentation of diamide derivatives of 3,4-ethylenedioxythiophene.
P2860
Q28645696-039E95F9-F4DE-4C56-BCB9-9BA486E6E5E4Q29048606-FFF2030B-0AFC-4E29-8232-1CF0B93E4F1FQ30636316-86A61AB4-2FDA-45A2-9119-66DF07B3A7E4Q30636326-EA22D128-14CA-4566-9D2D-2D2469B47846Q30656952-CE034D0C-F851-48A6-A5FC-994962E462DDQ30832615-59760150-F553-417F-A232-84E9496189FDQ31117765-3A18B584-4F69-4C6C-BDF7-6F85A1EF94FEQ33738123-85E52486-BE6B-462E-BB40-781FD75C4122Q33771433-AF71F346-4C94-4A74-9B7C-1570289202D0Q34167739-6C0FD29E-C1B3-4B3B-B5D0-6CA27B761D49Q34185397-48C138AB-0E55-4DF4-AAB2-F04DBA5E4049Q34191714-8C800EBF-5168-4612-8511-277CFF0AD370Q34519359-E66BED81-9593-4F7D-8977-C3BD82E4DAE9Q35235758-3642F96D-B957-4664-A732-A739E4C552C4Q35419675-5378B761-B115-41C1-8BAB-15851A3F4B83Q35688664-987E5A5D-1870-4E8B-9FAC-CEFBADA0D0F9Q35969906-440F6C14-41D5-45F2-B66D-9712AECFE567Q36225442-3D9DC4EA-2763-4428-B1A0-88F85290F2B1Q37512804-16898B74-DFAE-4347-BCF7-0B586BE866E0Q37963912-B34D1D12-206E-47AB-9991-560AFAC7C02AQ37986333-0E359B67-FF8A-478B-9799-52728DD2BDF7Q38005438-35211265-2520-4D39-88E2-D80F8691497BQ38026891-680250A0-9DE6-4D98-9BA3-D9E688CD4605Q38066995-8CE4F7BD-CA16-4CD6-9A81-9C881890A48BQ38071001-3387DE79-4DD0-4FF2-9461-46C53FFD9C65Q38081958-422B0AD6-1EE0-4EFD-82EA-FA51B9A691F6Q38093187-D007C013-9995-44E0-BFF7-8D6B39AFA980Q38110610-DCB1B438-52B6-4E66-ADFA-EC51144F8E1AQ38195300-8D4A78D4-DB77-44E4-8520-1FB650024149Q38339664-FCB3DA07-CFC3-4DF4-94F2-4592E863CA0AQ38620744-43B42CC0-203D-4048-874F-2A56884E0768Q38655633-A00750B7-120C-42A0-883C-8DCE5BBA6B5EQ38891334-0E7C0DAD-86F0-4722-8843-1FBD95CB7540Q38990711-44DA6F4E-DEB3-4EC9-90E1-6B5542DD494CQ39468169-E85DFF39-1118-4229-A724-53D387298C65Q39986492-89387A82-6AB7-435D-A247-3320E1861CCAQ40000228-F4E39D64-06A7-4BBA-A421-E65A443CB489Q40562448-EF6CAB7A-4DF5-442E-B4E8-2A8FB9457D8FQ41035651-96E9A1D2-4D0A-41BA-B763-84F077D78603Q44085403-06A4F381-2F7F-46CD-8D95-3710CD843E41
P2860
Drug metabolite profiling and identification by high-resolution mass spectrometry.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Drug metabolite profiling and identification by high-resolution mass spectrometry.
@en
Drug metabolite profiling and identification by high-resolution mass spectrometry.
@nl
type
label
Drug metabolite profiling and identification by high-resolution mass spectrometry.
@en
Drug metabolite profiling and identification by high-resolution mass spectrometry.
@nl
prefLabel
Drug metabolite profiling and identification by high-resolution mass spectrometry.
@en
Drug metabolite profiling and identification by high-resolution mass spectrometry.
@nl
P2860
P356
P1476
Drug metabolite profiling and identification by high-resolution mass spectrometry
@en
P2093
Mingshe Zhu
W Griffith Humphreys
P2860
P304
25419-25425
P356
10.1074/JBC.R110.200055
P407
P577
2011-06-01T00:00:00Z