Induction of mast cell proliferation, maturation, and heparin synthesis by the rat c-kit ligand, stem cell factor.
about
Emerging role of mast cells and macrophages in cardiovascular and metabolic diseasesMast cell proteoglycansChymase cleavage of stem cell factor yields a bioactive, soluble productKit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferationInterleukin-15 prevents mouse mast cell apoptosis through STAT6-mediated Bcl-xL expressionInduction of mast cell activation and CC chemokine responses in remodeling tracheal allograftsRabGEF1 regulates stem cell factor/c-Kit-mediated signaling events and biological responses in mast cellsA role for serglycin proteoglycan in granular retention and processing of mast cell secretory granule componentsFer kinase is required for sustained p38 kinase activation and maximal chemotaxis of activated mast cellsc-Kit-kinase induces a cascade of protein tyrosine phosphorylation in normal human melanocytes in response to mast cell growth factor and stimulates mitogen-activated protein kinase but is down-regulated in melanomas.Evaluation of the kinase domain of c-KIT in canine cutaneous mast cell tumors.Mast cell activation is characterized by upregulation of a functional anaphylatoxin C5a receptorInfection of mast cells with live streptococci causes a toll-like receptor 2- and cell-cell contact-dependent cytokine and chemokine responseMast-cell growth and differentiation.Biological implications of preformed mast cell mediators.The role of mast cells and their mediators in reproduction, pregnancy and labour.Our perception of the mast cell from Paul Ehrlich to now.Cardiac mast cells: the centrepiece in adverse myocardial remodelling.Committed mast cell progenitors in mouse blood differ in maturity between Th1 and Th2 strains.Gastrointestinal stromal tumors in a mouse model by targeted mutation of the Kit receptor tyrosine kinase.Class III receptor tyrosine kinases: role in leukaemogenesis.Modulation of mast cell proliferative and inflammatory responses by leukotriene d4 and stem cell factor signaling interactions.The role of c-KIT in tumorigenesis: evaluation in canine cutaneous mast cell tumors.Analyzing mast cell development and function using mice carrying mutations at W/c-kit or Sl/MGF (SCF) loci.Thymosin beta 4 expression in normal skin, colon mucosa and in tumor infiltrating mast cellsIn vivo immunological function of mast cells derived from embryonic stem cells: an approach for the rapid analysis of even embryonic lethal mutations in adult mice in vivo.Gastrointestinal stromal tumors: a paradigm for molecularly targeted therapy.Reversible expansion of primate mast cell populations in vivo by stem cell factor.The c-kit ligand, stem cell factor, promotes mast cell survival by suppressing apoptosis.p85β regulatory subunit of class IA PI3 kinase negatively regulates mast cell growth, maturation, and leukemogenesis.Analyzing the Functions of Mast Cells In Vivo Using 'Mast Cell Knock-in' MiceStem cell factor programs the mast cell activation phenotypeRegulation of mast cell responses in health and disease.Stem cell factor is responsible for the rapid response in mature mast cell density in the acutely stressed heart.Differential expression of secretory granule proteases in mouse mast cells exposed to interleukin 3 and c-kit ligandSteel factor influences the distribution and activity of murine hematopoietic stem cells in vivo.Mast Cells Participate in Corneal Development in Mice.Role of kit-ligand in proliferation and suppression of apoptosis in mast cells: basis for radiosensitivity of white spotting and steel mutant mice.Mouse bone marrow-derived mast cells (mBMMC) obtained in vitro from mice that are mast cell-deficient in vivo express the same panel of granule proteases as mBMMC and serosal mast cells from their normal littermatesThe immediate phase of c-kit ligand stimulation of mouse bone marrow-derived mast cells elicits rapid leukotriene C4 generation through posttranslational activation of cytosolic phospholipase A2 and 5-lipoxygenase.
P2860
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P2860
Induction of mast cell proliferation, maturation, and heparin synthesis by the rat c-kit ligand, stem cell factor.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Induction of mast cell prolife ...... -kit ligand, stem cell factor.
@en
Induction of mast cell prolife ...... -kit ligand, stem cell factor.
@nl
type
label
Induction of mast cell prolife ...... -kit ligand, stem cell factor.
@en
Induction of mast cell prolife ...... -kit ligand, stem cell factor.
@nl
prefLabel
Induction of mast cell prolife ...... -kit ligand, stem cell factor.
@en
Induction of mast cell prolife ...... -kit ligand, stem cell factor.
@nl
P2093
P2860
P356
P1476
Induction of mast cell prolife ...... -kit ligand, stem cell factor.
@en
P2093
D D Metcalfe
E N Geissler
H Thompson
K E Langley
T Takeishi
P2860
P304
P356
10.1073/PNAS.88.14.6382
P407
P577
1991-07-01T00:00:00Z