c-Kit-kinase induces a cascade of protein tyrosine phosphorylation in normal human melanocytes in response to mast cell growth factor and stimulates mitogen-activated protein kinase but is down-regulated in melanomas.
about
Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosisImmunohistochemical determination of HER-2/neu overexpression in malignant melanoma reveals no prognostic value, while c-Kit (CD117) overexpression exhibits potential therapeutic implicationsA Variant in a MicroRNA complementary site in the 3' UTR of the KIT oncogene increases risk of acral melanomaPhosphorylation of Shc by Src family kinases is necessary for stem cell factor receptor/c-kit mediated activation of the Ras/MAP kinase pathway and c-fos inductionMutations of c-kit JM domain are found in a minority of human gastrointestinal stromal tumors.Adenovirus-mediated CD40L gene transfer increases Teffector/Tregulatory cell ratio and upregulates death receptors in metastatic melanoma patients.Pigmented human skin equivalent--as a model of the mechanisms of control of cell-cell and cell-matrix interactions.Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder.Genetics of Cutaneous Malignant Melanoma.Tissue factor promotes melanoma metastasis by a pathway independent of blood coagulation.Understanding the biology of melanoma and therapeutic implicationsCorrelation between KIT expression and KIT mutation in melanoma: a study of 173 cases with emphasis on the acral-lentiginous/mucosal typeTerminal differentiation and senescence in the human melanocyte: repression of tyrosine-phosphorylation of the extracellular signal-regulated kinase 2 selectively defines the two phenotypes.A possible mechanism of mast cell proliferation in mastocytosis.c-KIT signaling is targeted by pathogenic Yersinia to suppress the host immune response.BRAF, KIT and NRAS mutations and expression of c-KIT, phosphorylated extracellular signal-regulated kinase and phosphorylated AKT in Japanese melanoma patients.The usefulness of c-Kit in the immunohistochemical assessment of melanocytic lesionsAHR promoter variant modulates its transcription and downstream effectors by allele-specific AHR-SP1 interaction functioning as a genetic marker for vitiligoRecombinant human stem cell factor (kit ligand) promotes human mast cell and melanocyte hyperplasia and functional activation in vivoStem cell factor expression, mast cells and inflammation in asthma.Murine cutaneous mastocytosis and epidermal melanocytosis induced by keratinocyte expression of transgenic stem cell factor.Phenotypic reversions at the W/Kit locus mediated by mitotic recombination in mice.Molecular targets in melanoma: time for 'ethnic personalization'Differential expression of c-kit and CD43 in histological subtypes of adenoid cystic carcinoma of salivary glandStem cell factor rescues tyrosinase expression and pigmentation in discreet anatomic locations in albino mice.Gain-of-function mutation of KIT ligand on melanin synthesis causes familial progressive hyperpigmentation.Antiserum raised against a synthetic phosphotyrosine-containing peptide selectively recognizes p185neu/erbB-2 and the epidermal growth factor receptor.Inhibition of c-Jun DNA binding by mitogen-activated protein kinase.Primary dermal melanoma: A case report and molecular characterization.Molecular biology of adenoid cystic carcinomaParacrine regulation of melanogenesis.A morphological and quantitative immunohistochemical study of the interstitial cells of Cajal in the normal equine intestinal tracts.Structural aspects of receptor dimerization. c-kit as an example.Expression and distribution of c-kit receptor and its ligand in human CNS germ cell tumors: a useful histological marker for the diagnosis of germinoma.The c-kit receptor, stem cell factor, and mast cells. What each is teaching us about the others.Pigmentation and proliferation of human melanocytes and the effects of melanocyte-stimulating hormone and ultraviolet B light.Structure-function analyses of the kit receptor for the steel factor.Lack of c-kit mutation in familial urticaria pigmentosa.recessive spotting: a linked locus that interacts with W/Kit but is not allelic.Clinical advances in mastocytosis.
P2860
Q22001442-3C3E45AB-C45D-4A07-B16E-A6D8E9D1D5DEQ24798111-34B0BA23-41E4-4C87-94AB-060BAC01CA0CQ27851611-6BF579C4-847D-47ED-8CF8-6379EAA4B016Q28145948-8DEB02A9-EC71-40C4-8903-15E65BD39E64Q30303666-FB4A1180-9144-48FC-B3A7-2F6E8446F957Q33587584-D1106074-76B2-4F57-882E-95907007AFD5Q33657494-708EED8A-9874-4813-955A-D9B18695A433Q33784323-494808EE-8F22-4AED-9F25-EFDD23D86C42Q33947423-CD79305E-4C07-45DE-B446-496351449434Q33956786-9DA847D9-FE02-46E7-9D5E-0515EA99B424Q33978378-460D9E0D-C6A1-4003-BD0C-D45065F7767EQ33995919-5884144E-EAD2-4E1B-B128-24D3BA286634Q34442407-863A9BD5-1155-4F87-95C3-DEE0D563677EQ34523898-436A4E49-31DA-4C27-A7B8-33726487B2BAQ35037308-9C4189C8-0911-4009-A625-64E34AB89BBDQ35576254-3401D48A-6EF8-4761-84ED-F93490BE793BQ35771115-0565B673-C6D2-45B7-BC8B-C8162106EAA9Q36060628-708EF1AB-DB53-46E3-808E-6D13CD2551C3Q36366794-15970003-FD59-4C3B-8D1B-AF0E538A2EA7Q36382616-AFD21385-02E1-49AE-AC74-1EA05EE43E99Q36400828-150D8299-D16B-40A5-A1B5-A8D738E449E7Q36555613-E26EC4FB-C013-4813-9A7B-10F5D93B11D0Q36927065-B08E0EF8-2F70-4BF9-8F48-0DA1D85422CFQ37044517-E930639B-EBDD-4608-8C94-1954D0F8F74FQ37130079-068E704E-65CB-40EA-BE35-55298BA1C065Q37189127-B15D37EC-00EC-4C64-AD16-60C35AEBA582Q37333311-E3AF1754-280A-4D52-9000-D030BFC7EA99Q37374463-AC1A9F6C-1300-47C0-8919-DE05904A851DQ37509190-1D6FF70F-2D83-4B73-8494-92C7F8BD5FE2Q37946780-67F949F9-C65D-40BD-B617-BC78334AE298Q39298695-D06E7438-858E-44B5-83A3-42F260D20112Q39866676-E74E8278-2DEB-4C26-B02B-246CE8AFFF62Q40374619-85B46B61-5055-4B99-A3AC-DEA506E39CCDQ40461031-72FE21C5-2FDD-4CC6-911C-F1663FFC1884Q40486326-2ED10C23-0D12-440D-A1DF-7F6F0D34879BQ40487497-46FA5992-0AE0-45A1-82C1-148CB1DB4B3BQ40490475-744DFB60-E463-426B-ACAB-B1032795CC47Q40810921-79201138-55A0-462D-93C8-7B2C91BADF49Q41025697-3D8EB28D-F102-42CF-8D1E-FBEDDC7E8399Q41097329-5CEC2222-52B8-4C3C-9DE7-A1A72B60B5CB
P2860
c-Kit-kinase induces a cascade of protein tyrosine phosphorylation in normal human melanocytes in response to mast cell growth factor and stimulates mitogen-activated protein kinase but is down-regulated in melanomas.
description
1992 nî lūn-bûn
@nan
1992 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
c-Kit-kinase induces a cascade ...... s down-regulated in melanomas.
@ast
c-Kit-kinase induces a cascade ...... s down-regulated in melanomas.
@en
type
label
c-Kit-kinase induces a cascade ...... s down-regulated in melanomas.
@ast
c-Kit-kinase induces a cascade ...... s down-regulated in melanomas.
@en
prefLabel
c-Kit-kinase induces a cascade ...... s down-regulated in melanomas.
@ast
c-Kit-kinase induces a cascade ...... s down-regulated in melanomas.
@en
P2093
P2860
P356
P1476
c-Kit-kinase induces a cascade ...... s down-regulated in melanomas.
@en
P2093
D E Williams
D M Anderson
Y Funasaka
P2860
P304
P356
10.1091/MBC.3.2.197
P577
1992-02-01T00:00:00Z