Interaction of hydrolysis-resistant analogs of cyclic GMP with the phosphodiesterase and light-sensitive channel of retinal rod outer segments.
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The pharmacology of cyclic nucleotide-gated channels: emerging from the darkness[7-(Dialkylamino)coumarin-4-yl]methyl-Caged Compounds as Ultrafast and Effective Long-Wavelength Phototriggers of 8-Bromo-Substituted Cyclic Nucleotides.Gating kinetics of the cyclic-GMP-activated channel of retinal rods: flash photolysis and voltage-jump studiesRod light adaptation may be mediated by acceleration of the phosphodiesterase-guanylate cyclase cycleExcised patches of plasma membrane from vertebrate rod outer segments retain a functional phototransduction enzymatic cascade.Direct activation of cGMP-dependent channels of retinal rods by the cGMP phosphodiesterase.Molecular origin of continuous dark noise in rod photoreceptorsMutating three residues in the bovine rod cyclic nucleotide-activated channel can switch a nucleotide from inactive to active.Single-channel recordings demonstrate that cGMP opens the light-sensitive ion channel of the rod photoreceptor.Identification, purification, and functional reconstitution of the cyclic GMP-dependent channel from rod photoreceptors.Purification and physiological evaluation of a guanylate cyclase activating protein from retinal rodsExploring light and life.Changes in cGMP concentration correlate with some, but not all, aspects of the light-regulated conductance of frog rod photoreceptorsDifferences in the protein composition of bovine retinal rod outer segment disk and plasma membranes isolated by a ricin-gold-dextran density perturbation method.Specific labeling and permanent activation of the retinal rod cGMP-activated channel by the photoaffinity analog 8-p-azidophenacylthio-cGMP.Transduction persists in rod photoreceptors after depletion of intracellular calciumNa+- and cGMP-induced Ca2+ fluxes in frog rod photoreceptorsRegulation by light of cyclic nucleotide-dependent protein kinases and their substrates in frog rod outer segments.Covalent activation of retinal rod cGMP-gated channels reveals a functional heterogeneity in the ligand binding sites.Time course and Ca(2+) dependence of sensitivity modulation in cyclic GMP-gated currents of intact cone photoreceptors.Fraction of the dark current carried by Ca(2+) through cGMP-gated ion channels of intact rod and cone photoreceptorsAngiotensin II-mediated hypertension impairs nitric oxide-induced NKCC2 inhibition in thick ascending limbs.Novel N7- and N1-substituted cGMP derivatives are potent activators of cyclic nucleotide-gated channels.The analysis of desensitizing CNGA1 channels reveals molecular interactions essential for normal gatingRole of calcium in regulating the cyclic GMP cascade of phototransduction in retinal rods.cGMP-dependent channel protein from photoreceptor membranes: single-channel activity of the purified and reconstituted protein.Light-dependent channels from excised patches of Limulus ventral photoreceptors are opened by cGMPGuanosine 3',5'-cyclic nucleotide binding proteins of bovine retina identified by photoaffinity labeling.New perspectives in cyclic nucleotide-mediated functions in the CNS: the emerging role of cyclic nucleotide-gated (CNG) channels.Recent progress in vertebrate photoreception.Absolute configuration of Rp-uridine 3',5'-cyclic phosphorothioate.Kinetics and components of the flash photocurrent of isolated retinal rods of the larval salamander, Ambystoma tigrinum.Inhibition of cGMP-dependent protein kinase by (Rp)-guanosine 3',5'-monophosphorothioates.Calcium modulation of ligand affinity in the cyclic GMP-gated ion channels of cone photoreceptors.In intact cone photoreceptors, a Ca2+-dependent, diffusible factor modulates the cGMP-gated ion channels differently than in rods.Fast adaptation in mouse olfactory sensory neurons does not require the activity of phosphodiesterase.Cyclic-nucleotide-gated channels mediate synaptic feedback by nitric oxide.In intact mammalian photoreceptors, Ca2+-dependent modulation of cGMP-gated ion channels is detectable in cones but not in rods.Locking CNGA1 channels in the open and closed state.Regulation of cGMP-dependent conductance in cytoplasmic membrane of rod outer segments by transducin.
P2860
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P2860
Interaction of hydrolysis-resistant analogs of cyclic GMP with the phosphodiesterase and light-sensitive channel of retinal rod outer segments.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 1985
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Interaction of hydrolysis-resi ...... of retinal rod outer segments.
@en
Interaction of hydrolysis-resi ...... of retinal rod outer segments.
@nl
type
label
Interaction of hydrolysis-resi ...... of retinal rod outer segments.
@en
Interaction of hydrolysis-resi ...... of retinal rod outer segments.
@nl
prefLabel
Interaction of hydrolysis-resi ...... of retinal rod outer segments.
@en
Interaction of hydrolysis-resi ...... of retinal rod outer segments.
@nl
P2093
P2860
P356
P1476
Interaction of hydrolysis-resi ...... of retinal rod outer segments.
@en
P2093
A L Zimmerman
D A Baylor
F Eckstein
G Yamanaka
P2860
P304
P356
10.1073/PNAS.82.24.8813
P407
P577
1985-12-01T00:00:00Z