Marine-sourced anti-cancer and cancer pain control agents in clinical and late preclinical development. - Wikidata - awgldk - TriplyDB

Marine-sourced anti-cancer and cancer pain control agents in clinical and late preclinical development.

Marine-sourced anti-cancer and cancer pain control agents in clinical and late preclinical development.

http://www.wikidata.org/entity/Q37566220

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Blue-Print Autophagy: Potential for Cancer Treatment Marine Invertebrate Metabolites with Anticancer Activities: Solutions to the "Supply Problem"Exploring the ocean for new drug developments: Marine pharmacology Anthraquinones and Derivatives from Marine-Derived Fungi: Structural Diversity and Selected Biological Activities Chemical Diversity and Biological Properties of Secondary Metabolites from Sea Hares of Aplysia Genus Marine Origin Polysaccharides in Drug Delivery Systems.Capturing Biological Activity in Natural Product Fragments by Chemical Synthesis Eribulin in the Management of Advanced Breast Cancer: Implications of Current Research Findings Tetrodotoxin, an Extremely Potent Marine Neurotoxin: Distribution, Toxicity, Origin and Therapeutical Uses Marine-Derived Pharmaceuticals - Challenges and Opportunities Investigation of the Anti-Inflammatory and Analgesic Activities of Ethanol Extract of Stem Bark of Sonapatha Oroxylum indicum In Vivo Metabolomic tools for secondary metabolite discovery from marine microbial symbionts Streptomyces malaysiense sp. nov.: A novel Malaysian mangrove soil actinobacterium with antioxidative activity and cytotoxic potential against human cancer cell lines.Phakellistatins: An Underwater Unsolved Puzzle.Peptides, Peptidomimetics, and Polypeptides from Marine Sources: A Wealth of Natural Sources for Pharmaceutical Applications.Marine Mollusk-Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy Resistance.Marine sponge derived natural products between 2001 and 2010: trends and opportunities for discovery of bioactives Coibamide A, a natural lariat depsipeptide, inhibits VEGFA/VEGFR2 expression and suppresses tumor growth in glioblastoma xenografts.Cytotoxic activity of ten algae from the Persian Gulf and Oman Sea on human breast cancer cell lines; MDA-MB-231, MCF-7, and T-47D Design, synthesis and in vitro cell-based evaluation of the anti-cancer activities of hispolon analogs.Endophytic and epiphytic microbes as "sources" of bioactive agents.Vitroprocines, new antibiotics against Acinetobacter baumannii, discovered from marine Vibrio sp. QWI-06 using mass-spectrometry-based metabolomics approach Activation of RAF1 (c-RAF) by the Marine Alkaloid Lasonolide A Induces Rapid Premature Chromosome Condensation.Can Some Marine-Derived Fungal Metabolites Become Actual Anticancer Agents?An anti-mycobacterial bisfunctionalized sphingolipid and new bromopyrrole alkaloid from the Indonesian marine sponge Agelas sp.Bioactive Polycyclic Quinones from Marine Streptomyces sp. 182SMLY.Crude Extracts of Marine-derived and Soil Fungi of the Genus Neosartorya Exhibit Selective Anticancer Activity by Inducing Cell Death in Colon, Breast and Skin Cancer Cell Lines.Marine Antibody-Drug Conjugates: Design Strategies and Research Progress.Review of natural compounds for potential skin cancer treatment.Natural product and natural product derived drugs in clinical trials.Natural products from marine organisms with neuroprotective activity in the experimental models of Alzheimer's disease, Parkinson's disease and ischemic brain stroke: their molecular targets and action mechanisms.Anticancer compounds from cyanobacterium Lyngbya species: a review.Trachycladines and Analogues: Synthesis and Evaluation of Anticancer Activity.Cytotoxic activity of Secondary Metabolites from Marine-derived Fungus Neosartorya siamensis in Human Cancer Cells.Current Status of Marine-Derived Compounds as Warheads in Anti-Tumor Drug Candidates.Tumor Protein (TP)-p53 Members as Regulators of Autophagy in Tumor Cells upon Marine Drug Exposure.Polyhydroxylated sulfated steroids derived from 5α-cholestanes as antiviral agents against herpes simplex virus.The marine triterpene glycoside frondoside A exhibits activity in vitro and in vivo in prostate cancer.Total Synthesis and Biological Assessment of Mandelalide A.Marine alkaloid Monanchocidin a overcomes drug resistance by induction of autophagy and lysosomal membrane permeabilization.

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Marine-sourced anti-cancer and cancer pain control agents in clinical and late preclinical development.

http://www.wikidata.org/entity/Q37566220

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 14 January 2014

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Marine-sourced anti-cancer and ...... late preclinical development.

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Marine-sourced anti-cancer and ...... late preclinical development.

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type

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Marine-sourced anti-cancer and ...... late preclinical development.

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Marine-sourced anti-cancer and ...... late preclinical development.

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prefLabel

Marine-sourced anti-cancer and ...... late preclinical development.

@en

Marine-sourced anti-cancer and ...... late preclinical development.

@nl

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Marine-sourced anti-cancer and ...... late preclinical development.

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David J Newman

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Gordon M Cragg

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Creative Commons Attribution 3.0 Unported

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The discovery of salinosporamide K from the marine bacterium "Salinispora pacifica" by genome mining gives insight into pathway evolution

Function-oriented biosynthesis of beta-lactone proteasome inhibitors in Salinispora tropica

Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica

Takeda's Oncology Discovery Strategy

Glycoprotein nonmetastatic B is an independent prognostic indicator of recurrence and a novel therapeutic target in breast cancer

CR011, a fully human monoclonal antibody-auristatin E conjugate, for the treatment of melanoma

New interfacial microtubule inhibitors of marine origin, PM050489/PM060184, with potent antitumor activity and a distinct mechanism.

First-in-man phase I trial of two schedules of the novel synthetic tetrahydroisoquinoline alkaloid PM00104 (Zalypsis) in patients with advanced solid tumours

Phase I study of PM00104 (Zalypsis®) administered as a 1-hour weekly infusion resting every fourth week in patients with advanced solid tumors.

A phase I pharmacokinetic study of PM00104 (Zalypsis) administered as a 24-h intravenous infusion every 3 weeks in patients with advanced solid tumors.

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10.3390/MD12010255

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