An 8-kilobase abl RNA transcript in chronic myelogenous leukemia.
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The first intron in the human c-abl gene is at least 200 kilobases long and is a target for translocations in chronic myelogenous leukemiaThe chronic myelocytic cell line K562 contains a breakpoint in bcr and produces a chimeric bcr/c-abl transcriptHuman chromosome 22.Characterization of a fusion cDNA (RARA/myl) transcribed from the t(15;17) translocation breakpoint in acute promyelocytic leukemia.cDNA sequence for human bcr, the gene that translocates to the abl oncogene in chronic myeloid leukaemiaChronic myelogenous leukaemia.The molecular biology of chromosome alterations in myelogenous leukemia.Mapping of four distinct BCR-related loci to chromosome region 22q11: order of BCR loci relative to chronic myelogenous leukemia and acute lymphoblastic leukemia breakpoints.Molecular analysis of TCRB and ABL in a t(7;9)-containing cell line (SUP-T3) from a human T-cell leukemia.Rapid Identification of Therapeutic Targets in Hematologic Malignancies via Functional Genomics.Philadelphia-positive leukemia: a personal perspective.Heterogeneity of chromosome 22 breakpoint in Philadelphia-positive (Ph+) acute lymphocytic leukemia.Restriction fragment length polymorphism caused by a deletion within the human c-abl gene (ABL).Variable expression of the translocated c-abl oncogene in Philadelphia-chromosome-positive B-lymphoid cell lines from chronic myelogenous leukemia patientsBCR translocation to derivative chromosome 2: a new case of chronic myeloid leukemia with a complex variant translocation and Philadelphia chromosomeT-cell immunity to the joining region of p210BCR-ABL proteinApplying the discovery of the Philadelphia chromosome.Phosphotyrosine antibodies identify the p210c-abl tyrosine kinase and proteins phosphorylated on tyrosine in human chronic myelogenous leukemia cellsComparison of constitutional and tumor-associated 11;22 translocations: nonidentical breakpoints on chromosomes 11 and 22p53 in chronic myelogenous leukemia in acute phase.c-src is consistently conserved in the chromosomal deletion (20q) observed in myeloid disordersChromosomal localization and characterization of c-abl in the t(6;9) of acute nonlymphocytic leukemiaMolecular techniques for the personalised management of patients with chronic myeloid leukaemia.Investigations regarding the utility of prodigiosenes to treat leukemia.Targeted next generation sequencing of clinically significant gene mutations and translocations in leukemia.The Philadelphia chromosome: from cytogenetics to oncogenes.Interactions of retroviral and cellular transforming genes with hematopoietic cells.Cytotoxic T cell response against the chimeric p210 BCR-ABL protein in patients with chronic myelogenous leukemia.The molecular biology of chronic myelogenous leukaemia.Evidence that the phl gene encodes a 160,000-dalton phosphoprotein with associated kinase activityInhibition of P210 expression in chronic myeloid leukaemia: oligonucleotides and/or transduced antisense sequences.Interferon-alpha and bcr-abl antisense oligodeoxynucleotides in combination enhance the antileukemic effect and the adherence of CML progenitors to preformed stroma.The presence of the Rb c-box peptide in the cytoplasm inhibits p210bcr-abl transforming function.Activation of class I HLA expression by TNF-alpha and gamma-interferon is mediated through protein kinase C-dependent pathway in CML cell lines.bcr Rearrangement without juxtaposition of c-abl in chronic myelocytic leukemia.Persistence of chronic myelocytic leukemia despite deletion of rearranged bcr/c-abl sequences in blast crisis.Inhibition of P210BCR/ABL Expression in K562 Cells by Electroporation with an Antisense Oligonucleotide.Chromosome and bcr rearrangement in chronic myelogenous leukaemia and their correlation with clinical states and prognosis of the disease.Molecular Diagnosis of the Philadelphia Chromosome in Acute Lymphoblastic Leukemia.
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P2860
An 8-kilobase abl RNA transcript in chronic myelogenous leukemia.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 1984
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
An 8-kilobase abl RNA transcript in chronic myelogenous leukemia.
@en
An 8-kilobase abl RNA transcript in chronic myelogenous leukemia.
@nl
type
label
An 8-kilobase abl RNA transcript in chronic myelogenous leukemia.
@en
An 8-kilobase abl RNA transcript in chronic myelogenous leukemia.
@nl
prefLabel
An 8-kilobase abl RNA transcript in chronic myelogenous leukemia.
@en
An 8-kilobase abl RNA transcript in chronic myelogenous leukemia.
@nl
P2860
P356
P1476
An 8-kilobase abl RNA transcript in chronic myelogenous leukemia.
@en
P2093
P2860
P304
P356
10.1073/PNAS.81.18.5648
P407
P577
1984-09-01T00:00:00Z