Class IIa HDACs: from important roles in differentiation to possible implications in tumourigenesis.
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Inhibition of the function of class IIa HDACs by blocking their interaction with MEF2Regulation of class IIa HDAC activities: it is not only matter of subcellular localizationPost-translational modifications regulate class IIa histone deacetylase (HDAC) function in health and diseaseThe bZIP repressor proteins, c-Jun dimerization protein 2 and activating transcription factor 3, recruit multiple HDAC members to the ATF3 promoterMEF2 is a converging hub for histone deacetylase 4 and phosphatidylinositol 3-kinase/Akt-induced transformation.Novel Class IIa-Selective Histone Deacetylase Inhibitors Discovered Using an in Silico Virtual Screening Approach.Myocyte enhancer factor (MEF)-2 plays essential roles in T-cell transformation associated with HTLV-1 infection by stabilizing complex between Tax and CREBMutagenesis Study Reveals the Rim of Catalytic Entry Site of HDAC4 and -5 as the Major Binding Surface of SMRT Corepressor14-3-3σ confers cisplatin resistance in esophageal squamous cell carcinoma cells via regulating DNA repair molecules.Dysregulated Class I histone deacetylases are indicators of poor prognosis in multiple myeloma.Nuclear Calcium/Calmodulin-dependent Protein Kinase II Signaling Enhances Cardiac Progenitor Cell Survival and Cardiac Lineage CommitmentAllele-specific imbalance mapping identifies HDAC9 as a candidate gene for cutaneous squamous cell carcinoma.Towards selective inhibition of histone deacetylase isoforms: what has been achieved, where we are and what will be next.Selective class IIa HDAC inhibitors: myth or reality.Overexpression of HDAC9 promotes oral squamous cell carcinoma growth, regulates cell cycle progression, and inhibits apoptosis.MC1568 inhibits HDAC6/8 activity and influenza A virus replication in lung epithelial cells: role of Hsp90 acetylation.Expression of HDAC9 in lung cancer--potential role in lung carcinogenesis.Transformation by different oncogenes relies on specific metabolic adaptations.CG200745, an HDAC inhibitor, induces anti-tumour effects in cholangiocarcinoma cell lines via miRNAs targeting the Hippo pathway.HDAC10 expression is associated with DNA mismatch repair gene and is a predictor of good prognosis in colon carcinoma.HDAC Inhibition Improves the Sarcoendoplasmic Reticulum Ca2+-ATPase Activity in Cardiac Myocytes.Synergistic Immunostimulatory Effects and Therapeutic Benefit of Combined Histone Deacetylase and Bromodomain Inhibition in Non-Small Cell Lung Cancer.The expression of HDAC7 in cancerous gastric tissues is positively associated with distant metastasis and poor patient prognosis.
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Class IIa HDACs: from important roles in differentiation to possible implications in tumourigenesis.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on September 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Class IIa HDACs: from importan ...... mplications in tumourigenesis.
@en
Class IIa HDACs: from importan ...... mplications in tumourigenesis.
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type
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Class IIa HDACs: from importan ...... mplications in tumourigenesis.
@en
Class IIa HDACs: from importan ...... mplications in tumourigenesis.
@nl
prefLabel
Class IIa HDACs: from importan ...... mplications in tumourigenesis.
@en
Class IIa HDACs: from importan ...... mplications in tumourigenesis.
@nl
P2860
P1476
Class IIa HDACs: from importan ...... implications in tumourigenesis
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P2093
Andrea Clocchiatti
Cristina Florean
P2860
P304
P356
10.1111/J.1582-4934.2011.01321.X
P577
2011-09-01T00:00:00Z