Efficacy of PLD-118, a novel inhibitor of candida isoleucyl-tRNA synthetase, against experimental oropharyngeal and esophageal candidiasis caused by fluconazole-resistant C. albicans.

Efficacy of PLD-118, a novel inhibitor of candida isoleucyl-tRNA synthetase, against experimental oropharyngeal and esophageal candidiasis caused by fluconazole-resistant C. albicans.

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http://www.wikidata.org/entity/Q37568979
Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug designOropharyngeal candidiasis in children with lymphohematopoietic malignancies in Mashhad, Iran.Prospects for aminoacyl-tRNA synthetase inhibitors as new antimicrobial agents.Recent progress on the topical therapy of onychomycosis.Aminoacyl-tRNA synthetases: essential and still promising targets for new anti-infective agents.Antifungal immunotherapy and immunomodulation: a double-hitter approach to deal with invasive fungal infections.Genetic validation of aminoacyl-tRNA synthetases as drug targets in Trypanosoma brucei.Addressing current medical needs in invasive fungal infection prevention and treatment with new antifungal agents, strategies and formulations.Immunotherapy of Fungal Infections.Antifungals: Mechanism of Action and Drug Resistance.In vitro activity and in vivo efficacy of icofungipen (PLD-118), a novel oral antifungal agent, against the pathogenic yeast Candida albicans.Amino Acid Metabolism and Transport Mechanisms as Potential Antifungal Targets.
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Efficacy of PLD-118, a novel inhibitor of candida isoleucyl-tRNA synthetase, against experimental oropharyngeal and esophageal candidiasis caused by fluconazole-resistant C. albicans.

Item
http://www.wikidata.org/entity/Q37568979
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Efficacy of PLD-118, a novel i ...... onazole-resistant C. albicans.
@en
Efficacy of PLD-118, a novel i ...... onazole-resistant C. albicans.
@nl
type
label
Efficacy of PLD-118, a novel i ...... onazole-resistant C. albicans.
@en
Efficacy of PLD-118, a novel i ...... onazole-resistant C. albicans.
@nl
prefLabel
Efficacy of PLD-118, a novel i ...... onazole-resistant C. albicans.
@en
Efficacy of PLD-118, a novel i ...... onazole-resistant C. albicans.
@nl
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Efficacy of PLD-118, a novel i ...... onazole-resistant C. albicans.
@en
P2093
P2860
P304
P31
P356
10.1128/AAC.48.10.3959-3967.2004
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